Bactericidal/permeability-increasing protein fold-containing family member A1 (BPIFA1), formerly known as SPLUNC1, participates in host protection through its antimicrobial, surfactant, and immunomodulatory properties [, ]. Its expression is largely restricted to the respiratory tract [].
This entry includes latherin, a surface-active allergen protein found in the sweat and saliva of horses []. Latherin exhibits a leucine content similar to BPIFA1 (bactericidal/permeability-increasing protein fold-containing family member A1), it is also surface-active, and may be involved in inhibition of microbial biofilms [, ].
