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Search results 1 to 1 out of 1 for Cilp2

Category restricted to ProteinDomain (x)

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Category: ProteinDomain
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Type Details Score
Protein Domain
IPR039675 | CILP1/CILP2
Type: Family
Description: This entry includes cartilage intermediate layer proteins 1 (CILP1) and 2 (CILP2). CILP1 acts as a modulator of lumbar disc disease susceptibility []. CILP1 interferes with pro-fibrotic TGFbeta signalling and is a mediator of cardiac extracellular matrix remodeling []. CILP2 is present in human articular cartilage and may be associated with collagen VI containing suprastructures [].
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