This entry represents Aftiphilin and related proteins from animals, including Uncharacterised protein CLBA1 (Clathrin-binding box of aftiphilin-containing protein 1). Aftin forms a stable complex with p200 and gamma-synergin []. It may play a role in membrane trafficking. Aftiphilin contains a clathrin box, with two identified clathrin-binding motifs [, ].