CXADR-like membrane protein (CLMP), also known as ACAM, belongs to the CTX family, whose members are type I transmembrane proteins within the immunoglobulin superfamily (IgSF). It is a component of epithelial tight junctions []. It has been implicated in adipocyte maturation and development of obesity []. Mutations of the CLMP gene cause Congenital Short Bowel Syndrome (CSBS) [].