Cytochrome c oxidase (CcO; ), a 13 subunit complex, is the terminal oxidase in the mitochondrial electron transport chain [, ]. Thisentry contains of cytochrome c oxidase subunit VIc, which is found only in eukaryotes and its specific function remains unclear. It has been reported that the relative concentrations of some nuclear encoded CcO subunits, including subunit VIc, compared to those of the mitochondrial encoded subunits, are altered significantly during the progression of prostate cancer [].
