The lipid-binding protein (LBP) family can be divided divided in four subfamiles. Subfamily I comprises proteins specific for vitamin A derivatives, and can be subdivided into the cellular retinoic acid-binding proteins (CRABP-I and II) and the cellular retinol-binding proteins (CRBP-I, II, III, and IV) [].This entry represents retinoic acid-binding protein 1 (CRABP-I). Upon binding retinoic acid (RA), CRABP I participates in RA catabolism by producingits inactive metabolites [].
