The cAMP-responsive element-binding protein-like 2 (CREBL2) is an uncharacterized protein containing a basic-leucine zipper (bZip) domain. Because of the location of the gene in a region frequently deleted in cancers, it has been suggested that CREBL2 is a tumour repressor [].This entry also includes REPTOR-BP from fruit flies. It is a transcriptional regulator that acts in the TORC1 signaling pathway to regulate energy homeostasis and promote survival during nutrient deprivation [].
