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Search results 1 to 1 out of 1 for Cubn

Category restricted to ProteinDomain (x)

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Category: ProteinDomain
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Type Details Score
Protein Domain
IPR056588 | EGF_LRP2
Type: Domain
Description: This EGF-like domain is found in human Low-density lipoprotein receptor-related protein 2 (LRP2) and similar animal proteins.LRP2 is a multi-ligand endocytic receptor. It acts together with CUBN to mediate endocytosis of high-density lipoproteins []. In the kidney, LRP2 mediates the tubular uptake and clearance of leptin [].
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