EHD (EH domain-containing protein) family is a group of endocytic recycling proteins that interact with ferlin proteins and mediate the cytoskeletal rearrangements necessary for proper membrane recycling and myoblast fusion []. Members in EHD family includes EHD1/2/3/4 []. This entry represents EHD2. It interacts with EHBP1 (EH domain-binding protein 1) and links clathrin-mediated endocytosis to the actin cytoskeleton [].
Myoferlin is a multi-C2 domain protein that belongs to the ferlin family, whose members are implicated in membrane-membrane fusion events []. It interacts with the endocytic recycling protein EHD2 and regulates myoblast fusion [].
Fer-1-like protein 5 is a multi-C2 domain protein that belongs to the ferlin family, whose members are implicated in membrane-membrane fusion events []. It interacts with endocytic recycling proteins EHD1 and EHD2 and mediates myoblast fusion [].