Saccharomyces cerevisiae ER membrane protein complex (EMC) comprises six subunits []. Four and three additional subunits have been identified in mammals and Drosophila, respectively []. EMC is required for protein folding in the endoplasmic reticulum (ER). It also facilitates lipid transfer from ER to mitochondria [].This family includes mammalian subunits EMC8 and EMC9, and Drosophila EMC8/9 homologue []. EMC8 is also known as neighbour of COX4 (NOC4) [].
