Ecotropic viral integration site 5 (Evi5) acts as a GTPase Activating Protein (GAP) for Rab11 in cytokinesis [, ]. Evi5 as an important factor in susceptibility to multiple sclerosis []. This entry also includes EAT-17 from Caenorhabditis elegans, which is a GAP that regulates RAB-6.2 function in grinder formation [].