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Search results 1 to 1 out of 1 for Fbxw2

Category restricted to ProteinDomain (x)

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Category: ProteinDomain
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Type Details Score
Protein Domain
IPR042627 | FBXW2
Type: Family
Description: F-box/WD repeat-containing protein 2 (FBXW2) is a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex []. It inhibits tumour migration, invasion and metastasis in lung cancer cells by targeting beta-catenin for degradation [].
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