This entry represents a group of four and a half LIM domains proteins (FHLs), including FHL2/3/5. The LIM domain is a conserved cysteine-rich module that provides protein-protein binding interfaces. FHL2 is one of the best studied FHL proteins. It is involved in a wide range of cellular processes, such as transcriptional regulation, signal transduction, and cell survival by binding to various protein partners [, ].
