|  Help  |  About  |  Contact Us

Search our database by keyword

- or -

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 1 out of 1 for Hhex

Category restricted to ProteinDomain (x)

0.014s

Categories

Category: ProteinDomain
« show all
Type Details Score
Protein Domain
IPR029547 | SOX-13
Type: Family
Description: SOX-13 is a HMG box transcription factor that binds to the sequence 5'-AACAAT-3' [, ]. It represses Wnt/TCF signaling by interacting with TCF1. It also interacts with Hhex (hematopoietically expressed homeobox), and this interaction displaces SOX13 from the SOX13 x TCF1 complex [].In humans, SOX-13 is an islet cell autoantigen (ICA12). Antibodies to SOX-13 are associated with type 1 diabetes [].
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom