This family of proteins is part of the short-chain dehydrogenases/reductases (SDR) superfamily. Despite their classification, these proteins are noted for lacking steroid dehydrogenase activity, which is typically associated with the SDR family. The exact biological function of these proteins remains unclear, but their conserved presence across different species suggests a potential role that is yet to be fully understood. The members of this family share a degree of sequence similarity indicative of a common evolutionary origin, and they may possess enzymatic activity that diverges from the canonical functions observed in other SDR family members.
