This entry includes mammalian intraflagellar transport protein 52 homolog (IFT52) and its homologues from bacteria. IFT52 is a component of the IFT complex B complex required for the movement of components required for the assembly, maintenance and function of primary cilia. Transport occurs in both directions []. Mutations in the IFT52 gene can lead to short-rib thoracic dysplasia 16 with or without polydactyly [].