Cysteine-rich protein 2-binding protein (KAT14) is a component of the ATAC complex. KAT14 may be the scaffold that stabilizes the complex [].The human ADA2A-containing complex (ATAC) is a histone acetyltransferase acting on histones H3 and H4 thatis similar to but distinct from a similar complex initially identified in Drosophila melanogaster. The ATAC complex is composed of KAT14, KAT2A, TADA2L, TADA3L, ZZZ3, MBIP, WDR5, YEATS2, CCDC101 and DR1 [].