This entry represents a group of kinesin-like proteins, including KIF15 from animals and KIN-12E from Arabidopsis. KIF15 homologues in Xenopus, Xklp2, is required for centrosome separation during mitosis []. KIN-12E has been shown to regulate metaphase spindle flux and help control spindle size in Arabidopsis [].
This domain corresponds to the C-terminal region of eukaryotic hyaluronan-mediated motility receptor protein (RHAMM), and may be involved in centrosome targeting []. This domain is also found C-terminal in kinesin-like protein KIF15 [].
