The structure of protein LURP-one-related 15 (At5g01750) has been solved. It comprises a 12-stranded beta barrel with a central C-terminal alpha helix. This helix is thought to be a transmembrane helix. It is structurally similar to the C-terminal domain of the Tubby protein []. In plants LURP1 plays a role in defense against pathogens [].
Lysine-oxoglutarate reductase/Saccharopine dehydrogenase (LOR/SDH) is a bifunctional enzyme. LOR is also known as LKR (lysine-ketoglutarate reductase), and thus LOR/SDH is sometimes termed LKR/SDH. This superfamily represents the conserved region, commonly found immediately N-terminal to saccharopine dehydrogenase conserved region in eukaryotes [, ].