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Search results 1 to 1 out of 1 for Mbd6

Category restricted to ProteinDomain (x)

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Category: ProteinDomain
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Type Details Score
Protein Domain
IPR037385 | MBD5/MBD6
Type: Family
Description: MBD5 and MBD6 are two members of the methyl-CpG-binding domain (MBD) family. They do not bind methylated DNA [], but instead they interact with the PR-DUB Polycomb protein complex in a mutually exclusive manner. They may share a function through their interaction with PR-DUB. MBD6, but not MBD5, is recruited to sites of DNA damage []. MBD5 is highly expressed in oocytes [].
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