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Search results 1 to 1 out of 1 for Ms4a6d

Category restricted to ProteinDomain (x)

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Category: ProteinDomain
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Type Details Score
Protein Domain
IPR030427 | MS4A6A-E
Type: Family
Description: MS4A6A/B/C/D/E are members of the membrane-spanning 4-domains family A (MS4A), which contains at least 16 members in human. MS4A6D has been shown to interact with VSIG4 to form a surface signaling complex, which activates JAK2-STAT3-A20 cascades to inhibit NF-kB activation []. MS4A6A and MS4A6E variants have been associated with Alzheimer's disease [, , ].
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