This domain is found in human Neuron navigator 1 (NAV1) and similar sequences from animals. NAV1 may be involved in neuronal migration. It is predicted to adopt a ubiquitin-like fold.
This ATPase lid domain is found towards the C-terminal end of human Cortactin-binding protein 2 (CortBP2), Neuron navigator 1 (NAV1) and similar animal proteins.CortBP2 regulates the dendritic spine distribution of CTTN/cortactin in hippocampal neurones and thus controls dendritic spinogenesis and dendritic spine maintenance []. NAV1 may be involved in neuronal migration and neurite outgrowth [].
