Nuclear factor erythroid 2-related factor 3 (NFe2L3, Nrf3) is a member of the Cap'n'Collar (CNC) family and is a basic-region leucine zipper (bZIP) transcription factor. NFe2L3 is a negative regulator of antioxidant-response element (ARE)-mediated gene expression []. It is involved in differentiation, inflammation, and carcinogenesis [].