This entry represents PACSIN3 (protein kinase C and casein kinase substrate in neurons protein 3), which belongs to the PACSIN family that contains a N-terminal F-BAR (FCH-BAR) domain and a C-terminal SH3 domain []. They are cytoplasmic phosphoproteins that play a role in vesicle formation and transport []. In mice, PACSIN3 helps to regulate the subcellular localisation of transient receptor potential channel TRPV4, and modulates its function in a stimulus-specific manner [, ]. Its overexpression increases adipocyte glucose transport through GLUT1 [].
