This entry represents a repeated region found in several Theileria parva proteins.The repeat is normally about 70 residues long and contains a conserved aromatic residue in the middle.
Members of this family are LenA (Leptospira Endostatin-like protein A), found in pathogenic and intermediate species of Leptospira but not in saprophytes. LenA binds plasminogen, laminin, and complement regulator factor H. Behavior during outer membrane solubilisation by low concentrations of Triton X-114 and conservation in all family members of an apparent lipoprotein signal sequence, with invariant Cys residue, strongly suggest that LenA is a lipoprotein. Just outside this family is a full-length homologue found in another spirochete, Turneriella parva DSM 21527 [].
