This entry represents the protein phosphatase 1 catalytic subunit (PP1c) binding region found in protein phosphatase 1 regulatory subunit 3A (PPP1R3A) and related proteins. PPP1R3A acts as a glycogen-targeting subunit for protein phosphatase 1 (PP1), which is essential for cell division and participates in the regulation of glycogen metabolism, muscle contractility, and protein synthesis [, ]. This domain mediates the interaction between the regulatory subunit and the PP1 catalytic subunit. In PPP1R3A, this binding region sits near the N terminus and is followed by a carbohydrate-binding type-21 (CBM21) domain that localises the complex to glycogen, as well as a long unannotated C-terminal region [, , ].
