This entry includes Arabidopsis thaliana AtGpp1 and AtGpp2, human pseudouridine-5'-phosphatase PUDP, the orthologue in Drosophila GS1-like protein (Dmel\Gs1l) []. AtGpp1 and AtGpp2 are constitutively expressed in all the Arabidopsis tissues and unaffected under abiotic stress. Overexpression of AtGpp2 in transgenic Arabidopsis plants increases the specific DL-glycerol-3-phosphatase activity and improves the plants tolerance to salt, osmotic and oxidative stress []. PUDP dephosphorylates pseudouridine 5'-phosphate, a potential intermediate in rRNA degradation [].
