This entry represents the RNA recognition motif 1 (RRM1) of vertebrate RNA-binding protein 4 (RBM4).RBM4 is a ubiquitously expressed splicing factor that has two isoforms, RBM4A (also known as Lark homologue) and RBM4B (also known as RBM30), which are very similar in structure and sequence. RBM4 is a RNA-binding protein involved in diverse cellular processes that include alternative splicing of pre-mRNA, translation, and RNA silencing []. RBM4 contains two N-terminal RNA recognition motifs (RRMs), a CCHC-type zinc finger, and three alanine-rich regions within their C-terminal regions. The RRMs, in combination with the C-terminal region, are responsible for the splicing function of RBM4 [].
This entry represents the RNA recognition motif 2 (RRM2) of vertebrate RNA-binding protein 4 (RBM4).RBM4 is a ubiquitously expressed splicing factor that has two isoforms, RBM4A (also known as Lark homologue) and RBM4B (also known as RBM30), which are very similar in structure and sequence. RBM4 is a RNA-binding protein involved in diverse cellular processes that include alternative splicing of pre-mRNA, translation, and RNA silencing []. RBM4 contains two N-terminal RNA recognition motifs (RRMs), a CCHC-type zinc finger, and three alanine-rich regions within their C-terminal regions. The RRMs, in combination with the C-terminal region, are responsible for the splicing function of RBM4 [].