RNA-binding protein 46 (RBM46) regulates trophectoderm specification by stabilising Cdx2 mRNA in early mouse embryos []. RBM46 contains three RNA recognition motifs (RRMs) and a C-terminal double-stranded RNA binding motif (DSR) []. This entry represents the DSR of RBM46.
RBM46 is also termed cancer/testis antigen 68 (CT68), a putative RNA-binding protein that shows high sequence homology with heterogeneous nuclear ribonucleoprotein R (hnRNP R) and heterogeneous nuclear ribonucleoprotein Q (hnRNP Q). Its biological function remains unclear. It has been shown to bind to and stabilize Cdx2 mRNA in early mouse embryos []. Like hnRNP R and hnRNP Q, RBM46 contains two well-defined and one degenerated RNA recognition motifs (RRMs) and a C-terminal double-stranded RNA binding motif (DSRM).This entry represents the RNA recognition motif 1 (RRM1) of RBM46.
RBM46 is also termed cancer/testis antigen 68 (CT68), a putative RNA-binding protein that shows high sequence homology with heterogeneous nuclear ribonucleoprotein R (hnRNP R) and heterogeneous nuclear ribonucleoprotein Q (hnRNP Q). Its biological function remains unclear. It has been shown to bind to and stabilize Cdx2 mRNA in early mouse embryos []. Like hnRNP R and hnRNP Q, RBM46 contains two well-defined and one degenerated RNA recognition motifs (RRMs) and a C-terminal double-stranded RNA binding motif (DSRM).This entry represents the RNA recognition motif 2 (RRM2) of RBM46.
