This entry represents regulator of G-protein signalling 9-binding protein (RGS9BP), which is involved in regulation of signalling in phototransduction []. It interacts with the regulation of G-protein signalling 9 (RGS9) and Gbeta5 complex, anchoring it to photoreceptor disc membranes [], enhancing the ability of RGS9 to stimulate G protein GTPase activity, allowing the visual signal to be terminated in a timely manner [].
This family consists of regulator of G-protein signalling 7-binding protein (RGS7BP) and regulator of G-protein signalling 9-binding protein (RGS9BP). They interact with regulation of G-protein signalling (RGS) proteins and Gbeta5 to form complexes that act to regulate G-proteins [].RGS7BP is expressed neuronally []and interacts with R7 family of RGS proteins (RGS6, RGS7, RGS9 and RGS11). RGS9BP interacts with RGS9 and is involved in the regulation of G-protein signalling in the phototransduction, participating in the recovery phase of visual transduction [].
