SMARCC1 (also known as BAF155) is a core component of the SWI/SNF complex, which is an ATP-dependent chromatin remodelling complex. BAF155 contains several domains such as the SANT, SWIRM, and leucine zipper domains. It may play an important role in stabilisation of the SWI/SNF complex []. It has been identified as a human tumour suppressor [, ].
This entry represents the N-terminal conserved domain found in the SWI/SNF complex subunits SMARCC1 (BAF155) and SMARCC2 (BAF170). The function of this domain is not clear.
This conserved domain can be found after the SWIRM and SANT domains in SWI/SNFcomplex subunits SMARCC1 (BAF155) and SMARCC2 (BAF170) []. The function of this domain is not clear.