This entry includes synaptonemal complex protein 2 (SYCP2) and synaptonemal complex protein 2-like (SYCP2L).SYCP2 is one of the major components of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase [].SYCP2L has partial sequence homology to a SYCP2 and is the major component of nucleolar cortical skeleton in Xenopus oocytes []. In humans, SYCP2L promotes primordial oocytes survival, thus being associated with age at natural menopause (ANM) [].
