Trichome birefringence-like (TBL) proteins are proposed to encode wall poly-saccharide specific O-acetyltransferases based on the existing data for some members of the TBL family: altered xyloglucan 4 (AXY4/TBL270) and altered xyloglucan 4-like (AXY4L/TBL22), two xyloglucan specific O-acetyltransferases in non-seed tissues and seeds, respectively [, ].
Transducin beta-like protein 2 (TBL2), also known as WBSCR13, has been linked to Williams-Beuren syndrome []. It contains an N-terminal transmembrane region and the C-terminal WD40 domain []. Under endoplasmic reticulum (ER) stress, TBL2 is involved in ATF4 translation through its association with the mRNA [].