This entry represents tetraspanin (TET) from plants, including TET1-17 from Arabidopsis. TET1, also known as TORNADO 2, is involved in the basipetal transport of auxin (IAA) that modulates growth and organs organization, as well as cell differentiation [, ]. It plays an role in cellular decisions in the peripheral zone of the shoot apical meristem []. Together with WIH1 and WIH2, TET1 promotes megasporogenesis [].Tetraspanins are a distinct family of proteins, containing four transmembrane domains: a small outer loop (EC1), a larger outer loop (EC2), a small inner loop (IL) and short cytoplasmic tails. They contain characteristic structural features, including 4-6 conserved extracellular cysteine residues, and polar residues within transmembrane domains. A fundamental role of tetraspanins appears to be organizing other proteins into a network of multimolecular membrane microdomains, sometimes called the 'tetraspanin web'.
