The function of TRAPPC2L (trafficking protein particle complex subunit 2-like) is not known, but evidence suggests that it is part of the TRAPP II complex required for distinct tethering events at Golgi membranes, playing a role in vesicular transport from endoplasmic reticulum to Golgi []. Mutations in the TRAPPC2L gene cause an autosomal recessive disease characterised by encephalopathy with episodic rhabdomyolysis [].