ZDHHC17 (also known as HIP14, huntingtin-interacting protein 14) is a palmitoyl acyltransferase (PAT) specific for a subset of neuronal proteins, including SNAP25, DLG4/PSD95, GAD2, SYT1 and HD. It may play a role in the pathogenesis of Huntington disease []. It also mediates Mg2+ transport and may play a role in cellular magnesium homeostasis [].