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Search results 1 to 100 out of 336 for Aire

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Category: Publication
Type Details Score
Publication
First Author: Mittaz L
Year: 1999
Journal: Biochem Biophys Res Commun
Title: Isolation and characterization of the mouse Aire gene.
Volume: 255
Issue: 2
Pages: 483-90
Publication
First Author: Kumar PG
Year: 2001
Journal: J Biol Chem
Title: The autoimmune regulator (AIRE) is a DNA-binding protein.
Volume: 276
Issue: 44
Pages: 41357-64
Publication
First Author: Anderson MS
Year: 2016
Journal: Nat Rev Immunol
Title: AIRE expands: new roles in immune tolerance and beyond.
Volume: 16
Issue: 4
Pages: 247-58
Publication
First Author: Oftedal BE
Year: 2015
Journal: Immunity
Title: Dominant Mutations in the Autoimmune Regulator AIRE Are Associated with Common Organ-Specific Autoimmune Diseases.
Volume: 42
Issue: 6
Pages: 1185-96
Publication
First Author: Finnish-German APECED Consortium.
Year: 1997
Journal: Nat Genet
Title: An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains.
Volume: 17
Issue: 4
Pages: 399-403
Publication
First Author: Heino M
Year: 1999
Journal: Biochem Biophys Res Commun
Title: Autoimmune regulator is expressed in the cells regulating immune tolerance in thymus medulla.
Volume: 257
Issue: 3
Pages: 821-5
Publication  
First Author: Petrusová J
Year: 2022
Journal: Cells
Title: AIRE in Male Fertility: A New Hypothesis.
Volume: 11
Issue: 19
Publication
First Author: Nakajima A
Year: 2014
Journal: PLoS One
Title: Commensal bacteria regulate thymic Aire expression.
Volume: 9
Issue: 8
Pages: e105904
Publication
First Author: Meredith M
Year: 2015
Journal: Nat Immunol
Title: Aire controls gene expression in the thymic epithelium with ordered stochasticity.
Volume: 16
Issue: 9
Pages: 942-9
Publication
First Author: Lindh E
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: AIRE regulates T-cell-independent B-cell responses through BAFF.
Volume: 105
Issue: 47
Pages: 18466-71
Publication
First Author: Liston A
Year: 2003
Journal: Nat Immunol
Title: Aire regulates negative selection of organ-specific T cells.
Volume: 4
Issue: 4
Pages: 350-4
Publication
First Author: Kawano H
Year: 2015
Journal: J Immunol
Title: Aire Expression Is Inherent to Most Medullary Thymic Epithelial Cells during Their Differentiation Program.
Volume: 195
Issue: 11
Pages: 5149-58
Publication
First Author: Jiang W
Year: 2005
Journal: J Exp Med
Title: Modifier loci condition autoimmunity provoked by Aire deficiency.
Volume: 202
Issue: 6
Pages: 805-15
Publication
First Author: Zhu ML
Year: 2013
Journal: Cancer Res
Title: Aire deficiency promotes TRP-1-specific immune rejection of melanoma.
Volume: 73
Issue: 7
Pages: 2104-16
Publication
First Author: Nishijima H
Year: 2022
Journal: J Immunol
Title: Aire Controls Heterogeneity of Medullary Thymic Epithelial Cells for the Expression of Self-Antigens.
Volume: 208
Issue: 2
Pages: 303-320
Publication
First Author: Anderson MS
Year: 2005
Journal: Immunity
Title: The cellular mechanism of Aire control of T cell tolerance.
Volume: 23
Issue: 2
Pages: 227-39
Publication
First Author: Dragin N
Year: 2016
Journal: J Clin Invest
Title: Estrogen-mediated downregulation of AIRE influences sexual dimorphism in autoimmune diseases.
Volume: 126
Issue: 4
Pages: 1525-37
Publication
First Author: Bin G
Year: 2012
Journal: Stem Cells Dev
Title: Aire promotes the self-renewal of embryonic stem cells through Lin28.
Volume: 21
Issue: 15
Pages: 2878-90
Publication
First Author: Ilmarinen T
Year: 2008
Journal: Mol Immunol
Title: Functional interaction of AIRE with PIAS1 in transcriptional regulation.
Volume: 45
Issue: 7
Pages: 1847-62
Publication
First Author: Guerau-de-Arellano M
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Transcriptional impact of Aire varies with cell type.
Volume: 105
Issue: 37
Pages: 14011-6
Publication    
First Author: Gu B
Year: 2017
Journal: Elife
Title: AIRE is a critical spindle-associated protein in embryonic stem cells.
Volume: 6
Publication
First Author: Waterfield M
Year: 2014
Journal: Nat Immunol
Title: The transcriptional regulator Aire coopts the repressive ATF7ip-MBD1 complex for the induction of immunotolerance.
Volume: 15
Issue: 3
Pages: 258-65
Publication
First Author: Koh AS
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Global relevance of Aire binding to hypomethylated lysine-4 of histone-3.
Volume: 107
Issue: 29
Pages: 13016-21
Publication
First Author: Kont V
Year: 2008
Journal: Mol Immunol
Title: Modulation of Aire regulates the expression of tissue-restricted antigens.
Volume: 45
Issue: 1
Pages: 25-33
Publication
First Author: Anderson MS
Year: 2002
Journal: Science
Title: Projection of an immunological self shadow within the thymus by the aire protein.
Volume: 298
Issue: 5597
Pages: 1395-401
Publication
First Author: Nishikawa Y
Year: 2014
Journal: J Immunol
Title: Temporal lineage tracing of Aire-expressing cells reveals a requirement for Aire in their maturation program.
Volume: 192
Issue: 6
Pages: 2585-92
Publication
First Author: Fujikado N
Year: 2016
Journal: Immunity
Title: Aire Inhibits the Generation of a Perinatal Population of Interleukin-17A-Producing γδ T Cells to Promote Immunologic Tolerance.
Volume: 45
Issue: 5
Pages: 999-1012
Publication
First Author: Huo F
Year: 2019
Journal: Immunobiology
Title: Aire deficient dendritic cells promote the T follicular helper cells differentiation.
Volume: 224
Issue: 4
Pages: 539-550
Publication
First Author: Dobeš J
Year: 2018
Journal: Eur J Immunol
Title: A novel conditional Aire allele enables cell-specific ablation of the immune tolerance regulator Aire.
Volume: 48
Issue: 3
Pages: 546-548
Publication
First Author: Schaller CE
Year: 2008
Journal: J Immunol
Title: Expression of Aire and the early wave of apoptosis in spermatogenesis.
Volume: 180
Issue: 3
Pages: 1338-43
Publication
First Author: Guerau-de-Arellano M
Year: 2009
Journal: J Exp Med
Title: Neonatal tolerance revisited: a perinatal window for Aire control of autoimmunity.
Volume: 206
Issue: 6
Pages: 1245-52
Publication      
First Author: Maglakelidze N
Year: 2022
Journal: J Invest Dermatol
Title: AIRE Deficiency Leads to the Development of Alopecia Areata‒Like Lesions in Mice.
Publication
First Author: Nishikawa Y
Year: 2010
Journal: J Exp Med
Title: Biphasic Aire expression in early embryos and in medullary thymic epithelial cells before end-stage terminal differentiation.
Volume: 207
Issue: 5
Pages: 963-71
Publication
First Author: Hobbs RP
Year: 2015
Journal: Nat Genet
Title: Keratin-dependent regulation of Aire and gene expression in skin tumor keratinocytes.
Volume: 47
Issue: 8
Pages: 933-8
Publication
First Author: Blechschmidt K
Year: 1999
Journal: Genome Res
Title: The mouse Aire gene: comparative genomic sequencing, gene organization, and expression.
Volume: 9
Issue: 2
Pages: 158-66
Publication
First Author: Morimoto J
Year: 2022
Journal: Cell Rep
Title: Aire suppresses CTLA-4 expression from the thymic stroma to control autoimmunity.
Volume: 38
Issue: 7
Pages: 110384
Publication
First Author: Koh AS
Year: 2018
Journal: Nat Immunol
Title: Rapid chromatin repression by Aire provides precise control of immune tolerance.
Volume: 19
Issue: 2
Pages: 162-172
Publication
First Author: Ramsey C
Year: 2002
Journal: Hum Mol Genet
Title: Aire deficient mice develop multiple features of APECED phenotype and show altered immune response.
Volume: 11
Issue: 4
Pages: 397-409
Publication
First Author: Haljasorg U
Year: 2015
Journal: Eur J Immunol
Title: A highly conserved NF-κB-responsive enhancer is critical for thymic expression of Aire in mice.
Volume: 45
Issue: 12
Pages: 3246-56
Publication
First Author: Venanzi ES
Year: 2007
Journal: J Immunol
Title: Lymphotoxin pathway and Aire influences on thymic medullary epithelial cells are unconnected.
Volume: 179
Issue: 9
Pages: 5693-700
Publication
First Author: Liston A
Year: 2004
Journal: J Exp Med
Title: Gene dosage--limiting role of Aire in thymic expression, clonal deletion, and organ-specific autoimmunity.
Volume: 200
Issue: 8
Pages: 1015-26
Publication
First Author: Daniely D
Year: 2010
Journal: J Immunol
Title: Diversity of TCRs on natural Foxp3+ T cells in mice lacking Aire expression.
Volume: 184
Issue: 12
Pages: 6865-73
Publication
First Author: Pöntynen N
Year: 2006
Journal: J Autoimmun
Title: Aire deficient mice do not develop the same profile of tissue-specific autoantibodies as APECED patients.
Volume: 27
Issue: 2
Pages: 96-104
Publication
First Author: Gillard GO
Year: 2007
Journal: J Immunol
Title: Aire-dependent alterations in medullary thymic epithelium indicate a role for Aire in thymic epithelial differentiation.
Volume: 178
Issue: 5
Pages: 3007-15
Publication  
First Author: Oliveira EH
Year: 2020
Journal: Front Immunol
Title: Aire Gene Influences the Length of the 3' UTR of mRNAs in Medullary Thymic Epithelial Cells.
Volume: 11
Pages: 1039
Publication
First Author: Giraud M
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Aire unleashes stalled RNA polymerase to induce ectopic gene expression in thymic epithelial cells.
Volume: 109
Issue: 2
Pages: 535-40
Publication
First Author: Hubert FX
Year: 2011
Journal: Blood
Title: Aire regulates the transfer of antigen from mTECs to dendritic cells for induction of thymic tolerance.
Volume: 118
Issue: 9
Pages: 2462-72
Publication
First Author: Org T
Year: 2009
Journal: Hum Mol Genet
Title: AIRE activated tissue specific genes have histone modifications associated with inactive chromatin.
Volume: 18
Issue: 24
Pages: 4699-710
Publication
First Author: Niki S
Year: 2006
Journal: J Clin Invest
Title: Alteration of intra-pancreatic target-organ specificity by abrogation of Aire in NOD mice.
Volume: 116
Issue: 5
Pages: 1292-301
Publication
First Author: Hamazaki Y
Year: 2007
Journal: Nat Immunol
Title: Medullary thymic epithelial cells expressing Aire represent a unique lineage derived from cells expressing claudin.
Volume: 8
Issue: 3
Pages: 304-11
Publication
First Author: Michelson DA
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: CTLA-4 on thymic epithelial cells complements Aire for T cell central tolerance.
Volume: 119
Issue: 48
Pages: e2215474119
Publication
First Author: Malchow S
Year: 2016
Journal: Immunity
Title: Aire Enforces Immune Tolerance by Directing Autoreactive T Cells into the Regulatory T Cell Lineage.
Volume: 44
Issue: 5
Pages: 1102-13
Publication
First Author: Cowan JE
Year: 2018
Journal: Eur J Immunol
Title: Aire controls the recirculation of murine Foxp3+ regulatory T-cells back to the thymus.
Volume: 48
Issue: 5
Pages: 844-854
Publication
First Author: Brännström J
Year: 2006
Journal: Clin Immunol
Title: Defect internalization and tyrosine kinase activation in Aire deficient antigen presenting cells exposed to Candida albicans antigens.
Volume: 121
Issue: 3
Pages: 265-73
Publication
First Author: Fletcher AL
Year: 2009
Journal: J Immunol
Title: Reduced thymic Aire expression and abnormal NF-kappa B2 signaling in a model of systemic autoimmunity.
Volume: 182
Issue: 5
Pages: 2690-9
Publication
First Author: Oven I
Year: 2007
Journal: Mol Cell Biol
Title: AIRE recruits P-TEFb for transcriptional elongation of target genes in medullary thymic epithelial cells.
Volume: 27
Issue: 24
Pages: 8815-23
Publication
First Author: Heinlein M
Year: 2022
Journal: Sci Immunol
Title: The acetyltransferase KAT7 is required for thymic epithelial cell expansion, expression of AIRE target genes, and thymic tolerance.
Volume: 7
Issue: 67
Pages: eabb6032
Publication
First Author: Hubert FX
Year: 2008
Journal: J Immunol
Title: A specific anti-Aire antibody reveals aire expression is restricted to medullary thymic epithelial cells and not expressed in periphery.
Volume: 180
Issue: 6
Pages: 3824-32
Publication
First Author: Sansom SN
Year: 2014
Journal: Genome Res
Title: Population and single-cell genomics reveal the Aire dependency, relief from Polycomb silencing, and distribution of self-antigen expression in thymic epithelia.
Volume: 24
Issue: 12
Pages: 1918-31
Publication
First Author: Mouri Y
Year: 2017
Journal: J Immunol
Title: Mode of Tolerance Induction and Requirement for Aire Are Governed by the Cell Types That Express Self-Antigen and Those That Present Antigen.
Volume: 199
Issue: 12
Pages: 3959-3971
Publication
First Author: Zuklys S
Year: 2000
Journal: J Immunol
Title: Normal thymic architecture and negative selection are associated with Aire expression, the gene defective in the autoimmune-polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED).
Volume: 165
Issue: 4
Pages: 1976-83
Publication
First Author: Yano M
Year: 2008
Journal: J Exp Med
Title: Aire controls the differentiation program of thymic epithelial cells in the medulla for the establishment of self-tolerance.
Volume: 205
Issue: 12
Pages: 2827-38
Publication
First Author: Zeng XL
Year: 2013
Journal: J Immunol
Title: Divergent effects of T cell costimulation and inflammatory cytokine production on autoimmune peripheral neuropathy provoked by Aire deficiency.
Volume: 190
Issue: 8
Pages: 3895-904
Publication
First Author: Yoshida H
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Brd4 bridges the transcriptional regulators, Aire and P-TEFb, to promote elongation of peripheral-tissue antigen transcripts in thymic stromal cells.
Volume: 112
Issue: 32
Pages: E4448-57
Publication  
First Author: Bansal K
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Aire regulates chromatin looping by evicting CTCF from domain boundaries and favoring accumulation of cohesin on superenhancers.
Volume: 118
Issue: 38
Publication
First Author: Giraud M
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: An RNAi screen for Aire cofactors reveals a role for Hnrnpl in polymerase release and Aire-activated ectopic transcription.
Volume: 111
Issue: 4
Pages: 1491-6
Publication
First Author: Danso-Abeam D
Year: 2013
Journal: Eur J Immunol
Title: Aire mediates thymic expression and tolerance of pancreatic antigens via an unconventional transcriptional mechanism.
Volume: 43
Issue: 1
Pages: 75-84
Publication
First Author: Misharin AV
Year: 2009
Journal: Endocrinology
Title: Studies in mice deficient for the autoimmune regulator (Aire) and transgenic for the thyrotropin receptor reveal a role for Aire in tolerance for thyroid autoantigens.
Volume: 150
Issue: 6
Pages: 2948-56
Publication
First Author: Yin M
Year: 2024
Journal: Proc Natl Acad Sci U S A
Title: Tracking the role of Aire in immune tolerance to the eye with a TCR transgenic mouse model.
Volume: 121
Issue: 5
Pages: e2311487121
Publication
First Author: Ferreirinha P
Year: 2021
Journal: Eur J Immunol
Title: A novel method to identify Post-Aire stages of medullary thymic epithelial cell differentiation.
Volume: 51
Issue: 2
Pages: 311-318
Publication
First Author: Yang S
Year: 2015
Journal: Science
Title: Immune tolerance. Regulatory T cells generated early in life play a distinct role in maintaining self-tolerance.
Volume: 348
Issue: 6234
Pages: 589-94
Publication
First Author: Chuprin A
Year: 2015
Journal: Nat Immunol
Title: The deacetylase Sirt1 is an essential regulator of Aire-mediated induction of central immunological tolerance.
Volume: 16
Issue: 7
Pages: 737-45
Publication
First Author: Gardner JM
Year: 2008
Journal: Science
Title: Deletional tolerance mediated by extrathymic Aire-expressing cells.
Volume: 321
Issue: 5890
Pages: 843-7
Publication
First Author: Herzig Y
Year: 2017
Journal: Nat Immunol
Title: Transcriptional programs that control expression of the autoimmune regulator gene Aire.
Volume: 18
Issue: 2
Pages: 161-172
Publication
First Author: Wang CY
Year: 1999
Journal: Genomics
Title: Cloning of Aire, the mouse homologue of the autoimmune regulator (AIRE) gene responsible for autoimmune polyglandular syndrome type 1 (ASP1).
Volume: 55
Issue: 3
Pages: 322-6
Publication
First Author: Ruan QG
Year: 2007
Journal: J Immunol
Title: The autoimmune regulator directly controls the expression of genes critical for thymic epithelial function.
Volume: 178
Issue: 11
Pages: 7173-80
Publication
First Author: Morimoto J
Year: 2023
Journal: J Immunol
Title: Cooperative but Distinct Role of Medullary Thymic Epithelial Cells and Dendritic Cells in the Production of Regulatory T Cells in the Thymus.
Volume: 210
Issue: 11
Pages: 1653-1666
Publication
First Author: Yamano T
Year: 2019
Journal: J Exp Med
Title: Aire-expressing ILC3-like cells in the lymph node display potent APC features.
Volume: 216
Issue: 5
Pages: 1027-1037
Publication
First Author: Gavanescu I
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Loss of Aire-dependent thymic expression of a peripheral tissue antigen renders it a target of autoimmunity.
Volume: 104
Issue: 11
Pages: 4583-7
Publication
First Author: Halonen M
Year: 2001
Journal: J Histochem Cytochem
Title: Subcellular location and expression pattern of autoimmune regulator (Aire), the mouse orthologue for human gene defective in autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED).
Volume: 49
Issue: 2
Pages: 197-208
Publication
First Author: Shum AK
Year: 2009
Journal: Sci Transl Med
Title: Identification of an autoantigen demonstrates a link between interstitial lung disease and a defect in central tolerance.
Volume: 1
Issue: 9
Pages: 9ra20
Publication
First Author: Kurisaki H
Year: 2013
Journal: PLoS One
Title: Autoimmune gastro-pancreatitis with anti-protein disulfide isomerase-associated 2 autoantibody in Aire-deficient BALB/cAnN mice.
Volume: 8
Issue: 8
Pages: e73862
Publication
First Author: Tuovinen H
Year: 2009
Journal: Cell Immunol
Title: gammadelta T cells develop independently of Aire.
Volume: 257
Issue: 1-2
Pages: 5-12
Publication
First Author: Su MA
Year: 2008
Journal: J Clin Invest
Title: Mechanisms of an autoimmunity syndrome in mice caused by a dominant mutation in Aire.
Volume: 118
Issue: 5
Pages: 1712-26
Publication    
First Author: Guyon C
Year: 2020
Journal: Elife
Title: Aire-dependent genes undergo Clp1-mediated 3'UTR shortening associated with higher transcript stability in the thymus.
Volume: 9
Publication      
First Author: Heng JS
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Comprehensive analysis of a mouse model of spontaneous uveoretinitis using single-cell RNA sequencing.
Publication
First Author: Ferguson BJ
Year: 2008
Journal: J Biol Chem
Title: AIRE's CARD revealed, a new structure for central tolerance provokes transcriptional plasticity.
Volume: 283
Issue: 3
Pages: 1723-31
Publication
First Author: LaFlam TN
Year: 2015
Journal: J Exp Med
Title: Identification of a novel cis-regulatory element essential for immune tolerance.
Volume: 212
Issue: 12
Pages: 1993-2002
Publication
First Author: Michel C
Year: 2017
Journal: J Immunol
Title: Revisiting the Road Map of Medullary Thymic Epithelial Cell Differentiation.
Volume: 199
Issue: 10
Pages: 3488-3503
Publication
First Author: DeVoss J
Year: 2006
Journal: J Exp Med
Title: Spontaneous autoimmunity prevented by thymic expression of a single self-antigen.
Volume: 203
Issue: 12
Pages: 2727-35
Publication  
First Author: Ferré EMN
Year: 2019
Journal: Sci Transl Med
Title: Lymphocyte-driven regional immunopathology in pneumonitis caused by impaired central immune tolerance.
Volume: 11
Issue: 495
Publication
First Author: Ramsey C
Year: 2006
Journal: Eur J Immunol
Title: Increased antigen presenting cell-mediated T cell activation in mice and patients without the autoimmune regulator.
Volume: 36
Issue: 2
Pages: 305-17
Publication
First Author: Träger U
Year: 2012
Journal: PLoS One
Title: The immune response to melanoma is limited by thymic selection of self-antigens.
Volume: 7
Issue: 4
Pages: e35005
Publication
First Author: Warren BD
Year: 2019
Journal: Biol Reprod
Title: Autoimmune Regulator is required in female mice for optimal embryonic development and implantation†.
Volume: 100
Issue: 6
Pages: 1492-1504
Publication
First Author: Hässler S
Year: 2006
Journal: Blood
Title: Aire-deficient mice develop hematopoetic irregularities and marginal zone B-cell lymphoma.
Volume: 108
Issue: 6
Pages: 1941-8
Publication
First Author: Zhou D
Year: 2012
Journal: Am J Pathol
Title: Critical involvement of macrophage infiltration in the development of Sjögren's syndrome-associated dry eye.
Volume: 181
Issue: 3
Pages: 753-60
Publication
First Author: Yang S
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Aire's plant homeodomain(PHD)-2 is critical for induction of immunological tolerance.
Volume: 110
Issue: 5
Pages: 1833-8
Publication  
First Author: Almaghrabi S
Year: 2023
Journal: Biomed Res Int
Title: Characterisation of APS-1 Experimental Models Is Crucial for Development of Novel Therapies.
Volume: 2023
Pages: 7960443
Publication
First Author: Gray D
Year: 2007
Journal: J Exp Med
Title: Proliferative arrest and rapid turnover of thymic epithelial cells expressing Aire.
Volume: 204
Issue: 11
Pages: 2521-8
Publication
First Author: Padonou F
Year: 2022
Journal: EMBO Rep
Title: Aire-dependent transcripts escape Raver2-induced splice-event inclusion in the thymic epithelium.
Volume: 23
Issue: 3
Pages: e53576