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Search results 1 to 100 out of 3228 for Shh

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Category: Publication
Type Details Score
Publication
First Author: Sagai T
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: SHH signaling mediated by a prechordal and brain enhancer controls forebrain organization.
Volume: 116
Issue: 47
Pages: 23636-23642
Publication
First Author: Harke J
Year: 2024
Journal: Mol Cell
Title: Multiple allelic configurations govern long-range Shh enhancer-promoter communication in the embryonic forebrain.
Volume: 84
Issue: 24
Pages: 4698-4710.e6
Publication
First Author: Zhao J
Year: 2009
Journal: Hum Mol Genet
Title: HnRNP U mediates the long-range regulation of Shh expression during limb development.
Volume: 18
Issue: 16
Pages: 3090-7
Publication
First Author: Sagai T
Year: 2009
Journal: Development
Title: A cluster of three long-range enhancers directs regional Shh expression in the epithelial linings.
Volume: 136
Issue: 10
Pages: 1665-74
Publication
First Author: Sagai T
Year: 2017
Journal: Sci Rep
Title: SHH signaling directed by two oral epithelium-specific enhancers controls tooth and oral development.
Volume: 7
Issue: 1
Pages: 13004
Publication
First Author: Williamson I
Year: 2016
Journal: Development
Title: Shh and ZRS enhancer colocalisation is specific to the zone of polarising activity.
Volume: 143
Issue: 16
Pages: 2994-3001
Publication
First Author: Sagai T
Year: 2005
Journal: Development
Title: Elimination of a long-range cis-regulatory module causes complete loss of limb-specific Shh expression and truncation of the mouse limb.
Volume: 132
Issue: 4
Pages: 797-803
Publication
First Author: Amano T
Year: 2009
Journal: Dev Cell
Title: Chromosomal dynamics at the Shh locus: limb bud-specific differential regulation of competence and active transcription.
Volume: 16
Issue: 1
Pages: 47-57
Publication
First Author: Büscher D
Year: 1998
Journal: Dev Dyn
Title: Expression profile of Gli family members and Shh in normal and mutant mouse limb development.
Volume: 211
Issue: 1
Pages: 88-96
Publication  
First Author: Sagai T
Year: 2017
Journal: Nat Commun
Title: Evolution of Shh endoderm enhancers during morphological transition from ventral lungs to dorsal gas bladder.
Volume: 8
Pages: 14300
Publication
First Author: Lettice LA
Year: 2003
Journal: Hum Mol Genet
Title: A long-range Shh enhancer regulates expression in the developing limb and fin and is associated with preaxial polydactyly.
Volume: 12
Issue: 14
Pages: 1725-35
Publication
First Author: Nemec S
Year: 2018
Journal: Dev Biol
Title: Shh signaling influences the phenotype of Pitx1-/- hindlimbs.
Volume: 439
Issue: 2
Pages: 65-68
Publication  
First Author: Crane-Smith Z
Year: 2021
Journal: Front Cell Dev Biol
Title: A Highly Conserved Shh Enhancer Coordinates Hypothalamic and Craniofacial Development.
Volume: 9
Pages: 595744
Publication
First Author: Bénazéraf B
Year: 2006
Journal: Dev Biol
Title: Identification of an unexpected link between the Shh pathway and a G2/M regulator, the phosphatase CDC25B.
Volume: 294
Issue: 1
Pages: 133-47
Publication
First Author: Michno K
Year: 2003
Journal: Dev Biol
Title: Shh expression is required for embryonic hair follicle but not mammary gland development.
Volume: 264
Issue: 1
Pages: 153-65
Publication
First Author: Anderson E
Year: 2014
Journal: Development
Title: Mapping the Shh long-range regulatory domain.
Volume: 141
Issue: 20
Pages: 3934-43
Publication
First Author: Krebs O
Year: 2003
Journal: Development
Title: Replicated anterior zeugopod (raz): a polydactylous mouse mutant with lowered Shh signaling in the limb bud.
Volume: 130
Issue: 24
Pages: 6037-47
Publication
First Author: Niedermaier M
Year: 2005
Journal: J Clin Invest
Title: An inversion involving the mouse Shh locus results in brachydactyly through dysregulation of Shh expression.
Volume: 115
Issue: 4
Pages: 900-9
Publication
First Author: Mouri K
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Enhancer adoption caused by genomic insertion elicits interdigital Shh expression and syndactyly in mouse.
Volume: 115
Issue: 5
Pages: 1021-1026
Publication
First Author: Himmelstein DS
Year: 2017
Journal: Dev Biol
Title: SHH E176/E177-Zn2+ conformation is required for signaling at endogenous sites.
Volume: 424
Issue: 2
Pages: 221-235
Publication
First Author: Paliou C
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Preformed chromatin topology assists transcriptional robustness of Shh during limb development.
Volume: 116
Issue: 25
Pages: 12390-12399
Publication
First Author: Cui CY
Year: 2011
Journal: Cell Cycle
Title: Shh is required for Tabby hair follicle development.
Volume: 10
Issue: 19
Pages: 3379-86
Publication
First Author: Murashima A
Year: 2014
Journal: Dev Biol
Title: Midline-derived Shh regulates mesonephric tubule formation through the paraxial mesoderm.
Volume: 386
Issue: 1
Pages: 216-26
Publication
First Author: Perez-Balaguer A
Year: 2009
Journal: Mech Dev
Title: Shh dependent and independent maintenance of basal midbrain.
Volume: 126
Issue: 5-6
Pages: 301-13
Publication
First Author: Tsukui T
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Multiple left-right asymmetry defects in Shh(-/-) mutant mice unveil a convergence of the shh and retinoic acid pathways in the control of Lefty-1.
Volume: 96
Issue: 20
Pages: 11376-81
Publication
First Author: Tan M
Year: 2006
Journal: Brain Res
Title: Gli3 mutation rescues the generation, but not the differentiation, of oligodendrocytes in Shh mutants.
Volume: 1067
Issue: 1
Pages: 158-63
Publication
First Author: Mill P
Year: 2005
Journal: Dev Cell
Title: Shh controls epithelial proliferation via independent pathways that converge on N-Myc.
Volume: 9
Issue: 2
Pages: 293-303
Publication
First Author: Lettice LA
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Disruption of a long-range cis-acting regulator for Shh causes preaxial polydactyly.
Volume: 99
Issue: 11
Pages: 7548-53
Publication
First Author: Bastida MF
Year: 2009
Journal: Development
Title: A BMP-Shh negative-feedback loop restricts Shh expression during limb development.
Volume: 136
Issue: 22
Pages: 3779-89
Publication
First Author: Ohkubo Y
Year: 2002
Journal: Neuroscience
Title: Coordinate regulation and synergistic actions of BMP4, SHH and FGF8 in the rostral prosencephalon regulate morphogenesis of the telencephalic and optic vesicles.
Volume: 111
Issue: 1
Pages: 1-17
Publication
First Author: Huang R
Year: 2023
Journal: J Biol Chem
Title: ISL1 regulates lung branching morphogenesis via Shh signaling pathway.
Volume: 299
Issue: 8
Pages: 105034
Publication
First Author: Hardcastle Z
Year: 1999
Journal: Cell Mol Biol (Noisy-le-grand)
Title: The Shh signalling pathway in early tooth development.
Volume: 45
Issue: 5
Pages: 567-78
Publication
First Author: Joksimovic M
Year: 2009
Journal: Nat Neurosci
Title: Wnt antagonism of Shh facilitates midbrain floor plate neurogenesis.
Volume: 12
Issue: 2
Pages: 125-31
Publication
First Author: Motoyama J
Year: 1998
Journal: Mech Dev
Title: Overlapping and non-overlapping Ptch2 expression with Shh during mouse embryogenesis.
Volume: 78
Issue: 1-2
Pages: 81-4
Publication
First Author: Cho G
Year: 2014
Journal: Dev Biol
Title: Arx together with FoxA2, regulates Shh floor plate expression.
Volume: 393
Issue: 1
Pages: 137-48
Publication
First Author: Litingtung Y
Year: 2000
Journal: Nat Neurosci
Title: Specification of ventral neuron types is mediated by an antagonistic interaction between Shh and Gli3.
Volume: 3
Issue: 10
Pages: 979-85
Publication
First Author: Li C
Year: 2005
Journal: Dev Biol
Title: Wnt5a regulates Shh and Fgf10 signaling during lung development.
Volume: 287
Issue: 1
Pages: 86-97
Publication
First Author: Lee JM
Year: 2011
Journal: Histochem Cell Biol
Title: Shh signaling is essential for rugae morphogenesis in mice.
Volume: 136
Issue: 6
Pages: 663-75
Publication
First Author: Kurosaka H
Year: 2015
Journal: PLoS One
Title: Cranial nerve development requires co-ordinated Shh and canonical Wnt signaling.
Volume: 10
Issue: 3
Pages: e0120821
Publication
First Author: Hayes L
Year: 2013
Journal: Dev Biol
Title: Duration of Shh signaling contributes to mDA neuron diversity.
Volume: 374
Issue: 1
Pages: 115-26
Publication
First Author: Balmer CW
Year: 2004
Journal: J Comp Neurol
Title: Loss of Gli3 and Shh function disrupts olfactory axon trajectories.
Volume: 472
Issue: 3
Pages: 292-307
Publication
First Author: Litingtung Y
Year: 2002
Journal: Nature
Title: Shh and Gli3 are dispensable for limb skeleton formation but regulate digit number and identity.
Volume: 418
Issue: 6901
Pages: 979-83
Publication
First Author: Suzuki K
Year: 2009
Journal: Development
Title: Embryonic hair follicle fate change by augmented beta-catenin through Shh and Bmp signaling.
Volume: 136
Issue: 3
Pages: 367-72
Publication
First Author: Allen BL
Year: 2007
Journal: Genes Dev
Title: The Hedgehog-binding proteins Gas1 and Cdo cooperate to positively regulate Shh signaling during mouse development.
Volume: 21
Issue: 10
Pages: 1244-57
Publication
First Author: Iwatsuki K
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Wnt signaling interacts with Shh to regulate taste papilla development.
Volume: 104
Issue: 7
Pages: 2253-8
Publication  
First Author: Fuccillo M
Year: 2006
Journal: Cereb Cortex
Title: Removal of Pax6 partially rescues the loss of ventral structures in Shh null mice.
Volume: 16 Suppl 1
Pages: i96-102
Publication
First Author: Winkler T
Year: 2014
Journal: PLoS One
Title: Wnt signaling activates Shh signaling in early postnatal intervertebral discs, and re-activates Shh signaling in old discs in the mouse.
Volume: 9
Issue: 6
Pages: e98444
Publication
First Author: Cai J
Year: 2005
Journal: Neuron
Title: Generation of oligodendrocyte precursor cells from mouse dorsal spinal cord independent of Nkx6 regulation and Shh signaling.
Volume: 45
Issue: 1
Pages: 41-53
Publication
First Author: Epstein DJ
Year: 2000
Journal: Development
Title: Members of the bHLH-PAS family regulate Shh transcription in forebrain regions of the mouse CNS.
Volume: 127
Issue: 21
Pages: 4701-9
Publication
First Author: Iulianella A
Year: 2018
Journal: Dev Dyn
Title: Ventral neural patterning in the absence of a Shh activity gradient from the floorplate.
Volume: 247
Issue: 1
Pages: 170-184
Publication
First Author: Oh S
Year: 2009
Journal: Dev Biol
Title: Shh and Gli3 activities are required for timely generation of motor neuron progenitors.
Volume: 331
Issue: 2
Pages: 261-9
Publication
First Author: Vierkotten J
Year: 2007
Journal: Development
Title: Ftm is a novel basal body protein of cilia involved in Shh signalling.
Volume: 134
Issue: 14
Pages: 2569-77
Publication
First Author: Li Y
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Cholesterol modification restricts the spread of Shh gradient in the limb bud.
Volume: 103
Issue: 17
Pages: 6548-53
Publication
First Author: Larkins CE
Year: 2011
Journal: Mol Biol Cell
Title: Arl13b regulates ciliogenesis and the dynamic localization of Shh signaling proteins.
Volume: 22
Issue: 23
Pages: 4694-703
Publication
First Author: Kim JY
Year: 2009
Journal: Dev Biol
Title: Shh and ROCK1 modulate the dynamic epithelial morphogenesis in circumvallate papilla development.
Volume: 325
Issue: 1
Pages: 273-80
Publication
First Author: Bai CB
Year: 2002
Journal: Development
Title: Gli2, but not Gli1, is required for initial Shh signaling and ectopic activation of the Shh pathway.
Volume: 129
Issue: 20
Pages: 4753-61
Publication  
First Author: Mecklenburg N
Year: 2021
Journal: Development
Title: Identification of disease-relevant modulators of the SHH pathway in the developing brain.
Volume: 148
Issue: 17
Publication
First Author: Rash BG
Year: 2011
Journal: Dev Biol
Title: Shh and Gli3 regulate formation of the telencephalic-diencephalic junction and suppress an isthmus-like signaling source in the forebrain.
Volume: 359
Issue: 2
Pages: 242-50
Publication
First Author: Maimets M
Year: 2022
Journal: Nat Commun
Title: Mesenchymal-epithelial crosstalk shapes intestinal regionalisation via Wnt and Shh signalling.
Volume: 13
Issue: 1
Pages: 715
Publication
First Author: Sanders TA
Year: 2013
Journal: Nature
Title: Specialized filopodia direct long-range transport of SHH during vertebrate tissue patterning.
Volume: 497
Issue: 7451
Pages: 628-32
Publication
First Author: Jeong Y
Year: 2003
Journal: Development
Title: Distinct regulators of Shh transcription in the floor plate and notochord indicate separate origins for these tissues in the mouse node.
Volume: 130
Issue: 16
Pages: 3891-902
Publication
First Author: Harfe BD
Year: 2004
Journal: Cell
Title: Evidence for an expansion-based temporal Shh gradient in specifying vertebrate digit identities.
Volume: 118
Issue: 4
Pages: 517-28
Publication
First Author: Zhang C
Year: 2025
Journal: FEBS J
Title: Transcriptional factor ISL1 regulates palate development by tuning the SHH cascade.
Volume: 292
Issue: 4
Pages: 851-863
Publication
First Author: Jeong Y
Year: 2008
Journal: Nat Genet
Title: Regulation of a remote Shh forebrain enhancer by the Six3 homeoprotein.
Volume: 40
Issue: 11
Pages: 1348-53
Publication
First Author: Zhu J
Year: 2011
Journal: Dev Dyn
Title: Analysis of mutants with altered shh activity and posterior digit loss supports a biphasic model for shh function as a morphogen and mitogen.
Volume: 240
Issue: 5
Pages: 1303-10
Publication
First Author: Lopez-Rios J
Year: 2014
Journal: Nature
Title: Attenuated sensing of SHH by Ptch1 underlies evolution of bovine limbs.
Volume: 511
Issue: 7507
Pages: 46-51
Publication
First Author: Vaillant C
Year: 2007
Journal: Development
Title: Protease nexin 1 and its receptor LRP modulate SHH signalling during cerebellar development.
Volume: 134
Issue: 9
Pages: 1745-54
Publication
First Author: Bell SM
Year: 2005
Journal: Dev Dyn
Title: Shh signaling in limb bud ectoderm: potential role in teratogen-induced postaxial ectrodactyly.
Volume: 233
Issue: 2
Pages: 313-25
Publication
First Author: Sloan TF
Year: 2015
Journal: PLoS Biol
Title: Integration of shallow gradients of Shh and Netrin-1 guides commissural axons.
Volume: 13
Issue: 3
Pages: e1002119
Publication
First Author: Ashique AM
Year: 2009
Journal: Sci Signal
Title: The Rfx4 transcription factor modulates Shh signaling by regional control of ciliogenesis.
Volume: 2
Issue: 95
Pages: ra70
Publication
First Author: Lin C
Year: 2009
Journal: Development
Title: Temporal and spatial dissection of Shh signaling in genital tubercle development.
Volume: 136
Issue: 23
Pages: 3959-67
Publication
First Author: Song L
Year: 2012
Journal: Cell Res
Title: Shh signaling guides spatial pathfinding of raphespinal tract axons by multidirectional repulsion.
Volume: 22
Issue: 4
Pages: 697-716
Publication
First Author: Ericson J
Year: 1997
Journal: Cell
Title: Pax6 controls progenitor cell identity and neuronal fate in response to graded Shh signaling.
Volume: 90
Issue: 1
Pages: 169-80
Publication
First Author: Ohazama A
Year: 2009
Journal: Development
Title: Primary cilia regulate Shh activity in the control of molar tooth number.
Volume: 136
Issue: 6
Pages: 897-903
Publication
First Author: Hardcastle Z
Year: 1998
Journal: Development
Title: The Shh signalling pathway in tooth development: defects in Gli2 and Gli3 mutants.
Volume: 125
Issue: 15
Pages: 2803-11
Publication
First Author: Nakatomi M
Year: 2013
Journal: J Dent Res
Title: Evc regulates a symmetrical response to Shh signaling in molar development.
Volume: 92
Issue: 3
Pages: 222-8
Publication
First Author: Oosterveen T
Year: 2012
Journal: Dev Cell
Title: Mechanistic differences in the transcriptional interpretation of local and long-range Shh morphogen signaling.
Volume: 23
Issue: 5
Pages: 1006-19
Publication
First Author: Leow CC
Year: 2009
Journal: J Biol Chem
Title: Prostate-specific Klf6 inactivation impairs anterior prostate branching morphogenesis through increased activation of the Shh pathway.
Volume: 284
Issue: 31
Pages: 21057-65
Publication
First Author: Sanz-Ezquerro JJ
Year: 2000
Journal: Development
Title: Autoregulation of Shh expression and Shh induction of cell death suggest a mechanism for modulating polarising activity during chick limb development.
Volume: 127
Issue: 22
Pages: 4811-23
Publication
First Author: Cui CY
Year: 2014
Journal: Development
Title: Involvement of Wnt, Eda and Shh at defined stages of sweat gland development.
Volume: 141
Issue: 19
Pages: 3752-60
Publication
First Author: Mazzonetto PC
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Mutation in NADPH oxidase 3 (NOX3) impairs SHH signaling and increases cerebellar neural stem/progenitor cell proliferation.
Volume: 1865
Issue: 6
Pages: 1502-1515
Publication
First Author: Schmidt S
Year: 2022
Journal: Nat Commun
Title: Primary cilia and SHH signaling impairments in human and mouse models of Parkinson's disease.
Volume: 13
Issue: 1
Pages: 4819
Publication
First Author: Taniguchi K
Year: 2012
Journal: PLoS Genet
Title: Loss of Tgif function causes holoprosencephaly by disrupting the SHH signaling pathway.
Volume: 8
Issue: 2
Pages: e1002524
Publication
First Author: Kozhemyakina E
Year: 2014
Journal: PLoS Genet
Title: GATA6 is a crucial regulator of Shh in the limb bud.
Volume: 10
Issue: 1
Pages: e1004072
Publication
First Author: Zeng L
Year: 2002
Journal: Genes Dev
Title: Shh establishes an Nkx3.2/Sox9 autoregulatory loop that is maintained by BMP signals to induce somitic chondrogenesis.
Volume: 16
Issue: 15
Pages: 1990-2005
Publication
First Author: Hovorakova M
Year: 2011
Journal: J Exp Zool B Mol Dev Evol
Title: Shh expression in a rudimentary tooth offers new insights into development of the mouse incisor.
Volume: 316
Issue: 5
Pages: 347-58
Publication  
First Author: Tsukiji N
Year: 2014
Journal: Mech Dev
Title: A novel regulatory element for Shh expression in the lung and gut of mouse embryos.
Volume: 131
Pages: 127-36
Publication
First Author: Hovorakova M
Year: 2013
Journal: J Exp Zool B Mol Dev Evol
Title: Sequential Shh expression in the development of the mouse upper functional incisor.
Volume: 320
Issue: 7
Pages: 455-64
Publication
First Author: Hatton BA
Year: 2006
Journal: Cancer Res
Title: N-myc is an essential downstream effector of Shh signaling during both normal and neoplastic cerebellar growth.
Volume: 66
Issue: 17
Pages: 8655-61
Publication
First Author: Ushiki A
Year: 2021
Journal: Nat Commun
Title: Deletion of CTCF sites in the SHH locus alters enhancer-promoter interactions and leads to acheiropodia.
Volume: 12
Issue: 1
Pages: 2282
Publication    
First Author: Noguchi H
Year: 2023
Journal: Elife
Title: Shh from mossy cells contributes to preventing NSC pool depletion after seizure-induced neurogenesis and in aging.
Volume: 12
Publication
First Author: Miyado M
Year: 2017
Journal: Reproduction
Title: Expression patterns of Fgf8 and Shh in the developing external genitalia of Suncus murinus.
Volume: 153
Issue: 2
Pages: 187-195
Publication
First Author: Hammerschmidt B
Year: 2007
Journal: Dev Biol
Title: Localization of Shh expression by Wnt and Eda affects axial polarity and shape of hairs.
Volume: 305
Issue: 1
Pages: 246-61
Publication
First Author: Castillo D
Year: 2014
Journal: Development
Title: Induction of ectopic taste buds by SHH reveals the competency and plasticity of adult lingual epithelium.
Volume: 141
Issue: 15
Pages: 2993-3002
Publication
First Author: Wang CK
Year: 2011
Journal: Dev Dyn
Title: Pleiotropic patterning response to activation of Shh signaling in the limb apical ectodermal ridge.
Volume: 240
Issue: 5
Pages: 1289-302
Publication
First Author: Galli A
Year: 2010
Journal: PLoS Genet
Title: Distinct roles of Hand2 in initiating polarity and posterior Shh expression during the onset of mouse limb bud development.
Volume: 6
Issue: 4
Pages: e1000901
Publication
First Author: Gustafsson MK
Year: 2002
Journal: Genes Dev
Title: Myf5 is a direct target of long-range Shh signaling and Gli regulation for muscle specification.
Volume: 16
Issue: 1
Pages: 114-26
Publication  
First Author: Shi X
Year: 2014
Journal: Nat Commun
Title: An epigenetic switch induced by Shh signalling regulates gene activation during development and medulloblastoma growth.
Volume: 5
Pages: 5425
Publication
First Author: Zhu XJ
Year: 2018
Journal: FEBS Lett
Title: Disruption of Wnt production in Shh lineage causes bone malformation in mice, mimicking human Malik-Percin-type syndactyly.
Volume: 592
Issue: 3
Pages: 356-368
Publication
First Author: Liem KF Jr
Year: 2012
Journal: J Cell Biol
Title: The IFT-A complex regulates Shh signaling through cilia structure and membrane protein trafficking.
Volume: 197
Issue: 6
Pages: 789-800