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Search results 101 to 200 out of 823 for Brca1

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Category: Publication
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Type Details Score
Publication
24914237 | J:215795
First Author: Broering TJ
Year: 2014
Journal: J Cell Biol
Title: BRCA1 establishes DNA damage signaling and pericentric heterochromatin of the X chromosome in male meiosis.
Volume: 205
Issue: 5
Pages: 663-75
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Publication
12642502 | J:82308
First Author: Xu X
Year: 2003
Journal: Development
Title: Impaired meiotic DNA-damage repair and lack of crossing-over during spermatogenesis in BRCA1 full-length isoform deficient mice.
Volume: 130
Issue: 9
Pages: 2001-12
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Publication
34815798 | J:314771
First Author: Sun H
Year: 2021
Journal: Theranostics
Title: Dissecting the heterogeneity and tumorigenesis of BRCA1 deficient mammary tumors via single cell RNA sequencing.
Volume: 11
Issue: 20
Pages: 9967-9987
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Publication
20046879 | J:155938
First Author: Quinn BA
Year: 2009
Journal: PLoS One
Title: Induction of ovarian leiomyosarcomas in mice by conditional inactivation of Brca1 and p53.
Volume: 4
Issue: 12
Pages: e8404
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Publication
38499540 | J:349049
First Author: Bidany-Mizrahi T
Year: 2024
Journal: Cell Death Discov
Title: Unveiling the relationship between WWOX and BRCA1 in mammary tumorigenicity and in DNA repair pathway selection.
Volume: 10
Issue: 1
Pages: 145
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Publication
18596218 | J:140893
First Author: Xiong B
Year: 2008
Journal: Biol Reprod
Title: BRCA1 is required for meiotic spindle assembly and spindle assembly checkpoint activation in mouse oocytes.
Volume: 79
Issue: 4
Pages: 718-26
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Publication
24013561 | J:211168
First Author: Kakarougkas A
Year: 2013
Journal: Nucleic Acids Res
Title: Co-operation of BRCA1 and POH1 relieves the barriers posed by 53BP1 and RAP80 to resection.
Volume: 41
Issue: 22
Pages: 10298-311
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Publication
38627785 | J:347355
First Author: Wang X
Year: 2024
Journal: BMC Biol
Title: GATA3 functions downstream of BRCA1 to promote DNA damage repair and suppress dedifferentiation in breast cancer.
Volume: 22
Issue: 1
Pages: 85
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Publication
10855792 | J:113897
First Author: Zhang H
Year: 2000
Journal: DNA Cell Biol
Title: VCP, a weak ATPase involved in multiple cellular events, interacts physically with BRCA1 in the nucleus of living cells.
Volume: 19
Issue: 5
Pages: 253-63
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Publication
10962568 | J:64358
First Author: Lane TF
Year: 2000
Journal: Oncogene
Title: Gene replacement with the human BRCA1 locus: tissue specific expression and rescue of embryonic lethality in mice.
Volume: 19
Issue: 36
Pages: 4085-90
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Publication
8760307 | J:34964
First Author: Zabludoff SD
Year: 1996
Journal: Oncogene
Title: BRCA1 mRNA is expressed highly during meiosis and spermiogenesis but not during mitosis of male germ cells.
Volume: 13
Issue: 3
Pages: 649-53
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Publication
23901102 | J:200687
First Author: Tian F
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: BRCA1 promotes the ubiquitination of PCNA and recruitment of translesion polymerases in response to replication blockade.
Volume: 110
Issue: 33
Pages: 13558-63
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Publication
19716796 | J:154193
First Author: Cao L
Year: 2009
Journal: Mol Cell
Title: A selective requirement for 53BP1 in the biological response to genomic instability induced by Brca1 deficiency.
Volume: 35
Issue: 4
Pages: 534-41
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Publication
22034435 | J:177853
First Author: Shakya R
Year: 2011
Journal: Science
Title: BRCA1 tumor suppression depends on BRCT phosphoprotein binding, but not its E3 ligase activity.
Volume: 334
Issue: 6055
Pages: 525-8
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Publication
30556208 | J:288679
First Author: Tarpey MD
Year: 2019
Journal: J Physiol
Title: Induced in vivo knockdown of the Brca1 gene in skeletal muscle results in skeletal muscle weakness.
Volume: 597
Issue: 3
Pages: 869-887
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Publication
9838122 | J:48003
First Author: Lin L
Year: 1998
Journal: Biochim Biophys Acta
Title: cDNA sequence and chromosomal localization of mouse Dlgh3 gene adjacent to the BRCA1 tumor suppressor locus.
Volume: 1443
Issue: 1-2
Pages: 211-6
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Publication
9207798 | J:41254
First Author: Hakem R
Year: 1997
Journal: Nat Genet
Title: Partial rescue of Brca1 (5-6) early embryonic lethality by p53 or p21 null mutation.
Volume: 16
Issue: 3
Pages: 298-302
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Publication
30352856 | J:266868
First Author: Sasanuma H
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: BRCA1 ensures genome integrity by eliminating estrogen-induced pathological topoisomerase II-DNA complexes.
Volume: 115
Issue: 45
Pages: E10642-E10651
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Publication
32139898 | J:302675
First Author: Chen J
Year: 2020
Journal: Cell Death Differ
Title: 53BP1 loss rescues embryonic lethality but not genomic instability of BRCA1 total knockout mice.
Volume: 27
Issue: 9
Pages: 2552-2567
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Publication
8674108 | J:33880
First Author: Hakem R
Year: 1996
Journal: Cell
Title: The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse.
Volume: 85
Issue: 7
Pages: 1009-23
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Publication
15797026 | J:97090
First Author: Chodankar R
Year: 2005
Journal: Curr Biol
Title: Cell-nonautonomous induction of ovarian and uterine serous cystadenomas in mice lacking a functional Brca1 in ovarian granulosa cells.
Volume: 15
Issue: 6
Pages: 561-5
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Publication
11077440 | J:65877
First Author: Mixon M
Year: 2000
Journal: Oncogene
Title: Expression of Brca1 and splice variant Brca1delta11 RNA levels in mouse mammary gland during normal development and tumorigenesis.
Volume: 19
Issue: 46
Pages: 5237-43
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Publication
11431698 | J:70271
First Author: Xu X
Year: 2001
Journal: Nat Genet
Title: Genetic interactions between tumor suppressors Brca1 and p53 in apoptosis, cell cycle and tumorigenesis.
Volume: 28
Issue: 3
Pages: 266-71
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9872327 | J:51834
First Author: Shen SX
Year: 1998
Journal: Oncogene
Title: A targeted disruption of the murine Brca1 gene causes gamma-irradiation hypersensitivity and genetic instability.
Volume: 17
Issue: 24
Pages: 3115-24
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Publication
7590247 | J:29684
First Author: Lane TF
Year: 1995
Journal: Genes Dev
Title: Expression of Brca1 is associated with terminal differentiation of ectodermally and mesodermally derived tissues in mice.
Volume: 9
Issue: 21
Pages: 2712-22
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Publication
16675955 | J:108783
First Author: Cao L
Year: 2006
Journal: EMBO J
Title: ATM-Chk2-p53 activation prevents tumorigenesis at an expense of organ homeostasis upon Brca1 deficiency.
Volume: 25
Issue: 10
Pages: 2167-77
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Publication
8566965 | J:31275
First Author: Schröck E
Year: 1996
Journal: Hum Genet
Title: The murine homolog of the human breast and ovarian cancer susceptibility gene Brca1 maps to mouse chromosome 11D.
Volume: 97
Issue: 2
Pages: 256-9
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Publication
35236825 | J:321831
First Author: Bai F
Year: 2022
Journal: Cell Death Dis
Title: Loss of function of BRCA1 promotes EMT in mammary tumors through activation of TGFβR2 signaling pathway.
Volume: 13
Issue: 3
Pages: 195
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Publication
22488153 | J:184703
First Author: Yen HY
Year: 2012
Journal: Lab Invest
Title: Alterations in Brca1 expression in mouse ovarian granulosa cells have short-term and long-term consequences on estrogen-responsive organs.
Volume: 92
Issue: 6
Pages: 802-11
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Publication
22777348 | J:198018
First Author: Bai F
Year: 2013
Journal: Oncogene
Title: Germline mutation of Brca1 alters the fate of mammary luminal cells and causes luminal-to-basal mammary tumor transformation.
Volume: 32
Issue: 22
Pages: 2715-25
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Publication
14729266 | J:87912
 
First Author: Whitehouse C
Year: 2004
Journal: Gene
Title: Brca1 expression is regulated by a bidirectional promoter that is shared by the Nbr1 gene in mouse.
Volume: 326
Pages: 87-96
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15123655 | J:91673
First Author: Wang X
Year: 2004
Journal: J Biol Chem
Title: Genetic interactions between Brca1 and Gadd45a in centrosome duplication, genetic stability, and neural tube closure.
Volume: 279
Issue: 28
Pages: 29606-14
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7550308 | J:28391
First Author: Marquis ST
Year: 1995
Journal: Nat Genet
Title: The developmental pattern of Brca1 expression implies a role in differentiation of the breast and other tissues.
Volume: 11
Issue: 1
Pages: 17-26
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Publication
38359745 | J:345612
 
First Author: Drake DM
Year: 2024
Journal: Redox Biol
Title: BRCA1 protein dose-dependent risk for embryonic oxidative DNA damage, embryopathies and neurodevelopmental disorders with and without ethanol exposure.
Volume: 70
Pages: 103070
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16204043 | J:102687
First Author: Bowen TJ
Year: 2005
Journal: Cancer Res
Title: Atm heterozygosity cooperates with loss of Brca1 to increase the severity of mammary gland cancer and reduce ductal branching.
Volume: 65
Issue: 19
Pages: 8736-46
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17070800 | J:117113
First Author: Clark-Knowles KV
Year: 2007
Journal: Exp Cell Res
Title: Conditional inactivation of Brca1 in the mouse ovarian surface epithelium results in an increase in preneoplastic changes.
Volume: 313
Issue: 1
Pages: 133-45
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Publication
38149669 | J:344122
 
First Author: Tornillo G
Year: 2024
Journal: Dis Model Mech
Title: Conditional in vivo deletion of LYN kinase has little effect on a BRCA1 loss-of-function-associated mammary tumour model.
Volume: 17
Issue: 1
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17363841 | J:122899
First Author: Cao L
Year: 2007
Journal: Carcinogenesis
Title: Absence of full-length Brca1 sensitizes mice to oxidative stress and carcinogen-induced tumorigenesis in the esophagus and forestomach.
Volume: 28
Issue: 7
Pages: 1401-7
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Publication
29718910 | J:263685
First Author: Kitami K
Year: 2018
Journal: PLoS Genet
Title: BRCA1 and BRCA2 tumor suppressors in neural crest cells are essential for craniofacial bone development.
Volume: 14
Issue: 5
Pages: e1007340
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9774970 | J:113839
First Author: Chen J
Year: 1998
Journal: Mol Cell
Title: Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells.
Volume: 2
Issue: 3
Pages: 317-28
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10910057 | J:206999
First Author: Bennett LM
Year: 2000
Journal: Cancer Res
Title: Mice heterozygous for a Brca1 or Brca2 mutation display distinct mammary gland and ovarian phenotypes in response to diethylstilbestrol.
Volume: 60
Issue: 13
Pages: 3461-9
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11181458 | J:67485
First Author: Karabinis ME
Year: 2001
Journal: Carcinogenesis
Title: Heterozygosity for a mutation in Brca1 or Atm does not increase susceptibility to ENU-induced mammary tumors in Apc(Min)/+ mice.
Volume: 22
Issue: 2
Pages: 343-6
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25943777 | J:319107
First Author: Upton DH
Year: 2015
Journal: Horm Cancer
Title: Granulosa Cell-Specific Brca1 Loss Alone or Combined with Trp53 Haploinsufficiency and Transgenic FSH Expression Fails to Induce Ovarian Tumors.
Volume: 6
Issue: 4
Pages: 142-52
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11420664 | J:69602
First Author: Hohenstein P
Year: 2001
Journal: Oncogene
Title: A targeted mouse Brca1 mutation removing the last BRCT repeat results in apoptosis and embryonic lethality at the headfold stage.
Volume: 20
Issue: 20
Pages: 2544-50
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Publication
18461147 | J:161107
First Author: Vassilopoulos A
Year: 2008
Journal: Int J Biol Sci
Title: Identification and characterization of cancer initiating cells from BRCA1 related mammary tumors using markers for normal mammary stem cells.
Volume: 4
Issue: 3
Pages: 133-42
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Publication
30445628 | J:277844
First Author: Xu X
Year: 2019
Journal: Hum Mol Genet
Title: BRCA1 represses DNA replication initiation through antagonizing estrogen signaling and maintains genome stability in parallel with WEE1-MCM2 signaling during pregnancy.
Volume: 28
Issue: 5
Pages: 842-857
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Publication
19088202 | J:197744
First Author: Reid LJ
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: E3 ligase activity of BRCA1 is not essential for mammalian cell viability or homology-directed repair of double-strand DNA breaks.
Volume: 105
Issue: 52
Pages: 20876-81
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17626182 | J:126551
First Author: Liu X
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Somatic loss of BRCA1 and p53 in mice induces mammary tumors with features of human BRCA1-mutated basal-like breast cancer.
Volume: 104
Issue: 29
Pages: 12111-6
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9133444 | J:40064
First Author: Rajan JV
Year: 1997
Journal: Dev Biol
Title: Developmental expression of Brca2 colocalizes with Brca1 and is associated with proliferation and differentiation in multiple tissues.
Volume: 184
Issue: 2
Pages: 385-401
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Publication
37697435 | J:342028
First Author: Krishnan R
Year: 2023
Journal: Nucleic Acids Res
Title: RNF8 ubiquitylation of XRN2 facilitates R-loop resolution and restrains genomic instability in BRCA1 mutant cells.
Volume: 51
Issue: 19
Pages: 10484-10505
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25066119 | J:269823
First Author: Castillo A
Year: 2014
Journal: Cell Rep
Title: The BRCA1-interacting protein Abraxas is required for genomic stability and tumor suppression.
Volume: 8
Issue: 3
Pages: 807-17
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17653086 | J:132088
First Author: Jones LP
Year: 2008
Journal: Oncogene
Title: Activation of estrogen signaling pathways collaborates with loss of Brca1 to promote development of ERalpha-negative and ERalpha-positive mammary preneoplasia and cancer.
Volume: 27
Issue: 6
Pages: 794-802
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22617326 | J:189304
First Author: Szabova L
Year: 2012
Journal: Cancer Res
Title: Perturbation of Rb, p53, and Brca1 or Brca2 cooperate in inducing metastatic serous epithelial ovarian cancer.
Volume: 72
Issue: 16
Pages: 4141-53
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23271346 | J:192592
First Author: Sotiropoulou PA
Year: 2013
Journal: Genes Dev
Title: BRCA1 deficiency in skin epidermis leads to selective loss of hair follicle stem cells and their progeny.
Volume: 27
Issue: 1
Pages: 39-51
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23509290 | J:194229
First Author: Kass EM
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Double-strand break repair by homologous recombination in primary mouse somatic cells requires BRCA1 but not the ATM kinase.
Volume: 110
Issue: 14
Pages: 5564-9
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Publication
28659469 | J:244006
First Author: Chen CC
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: ATM loss leads to synthetic lethality in BRCA1 BRCT mutant mice associated with exacerbated defects in homology-directed repair.
Volume: 114
Issue: 29
Pages: 7665-7670
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20028858 | J:155737
First Author: Hong H
Year: 2010
Journal: Cancer Res
Title: Changes in the mouse estrus cycle in response to BRCA1 inactivation suggest a potential link between risk factors for familial and sporadic ovarian cancer.
Volume: 70
Issue: 1
Pages: 221-8
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Publication
20616007 | J:162412
First Author: Whitehouse CA
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Neighbor of Brca1 gene (Nbr1) functions as a negative regulator of postnatal osteoblastic bone formation and p38 MAPK activity.
Volume: 107
Issue: 29
Pages: 12913-8
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19403657 | J:149563
First Author: Pulvers JN
Year: 2009
Journal: Development
Title: Brca1 is required for embryonic development of the mouse cerebral cortex to normal size by preventing apoptosis of early neural progenitors.
Volume: 136
Issue: 11
Pages: 1859-68
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23664366 | J:197441
First Author: Nakles RE
Year: 2013
Journal: Am J Pathol
Title: The PPARγ agonist efatutazone increases the spectrum of well-differentiated mammary cancer subtypes initiated by loss of full-length BRCA1 in association with TP53 haploinsufficiency.
Volume: 182
Issue: 6
Pages: 1976-85
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Publication
29401626 | J:272130
First Author: Jackson KC
Year: 2018
Journal: FASEB J
Title: Induced Cre-mediated knockdown of Brca1 in skeletal muscle reduces mitochondrial respiration and prevents glucose intolerance in adult mice on a high-fat diet.
Volume: 32
Issue: 6
Pages: 3070-3084
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Publication
24829461 | J:218138
First Author: Muñoz MC
Year: 2014
Journal: Nucleic Acids Res
Title: An RNF168 fragment defective for focal accumulation at DNA damage is proficient for inhibition of homologous recombination in BRCA1 deficient cells.
Volume: 42
Issue: 12
Pages: 7720-33
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26903517 | J:233720
First Author: Hodge CD
Year: 2016
Journal: J Biol Chem
Title: RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor Recruitment.
Volume: 291
Issue: 18
Pages: 9396-410
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30484104 | J:307676
First Author: Hollern DP
Year: 2019
Journal: Breast Cancer Res Treat
Title: A mouse model featuring tissue-specific deletion of p53 and Brca1 gives rise to mammary tumors with genomic and transcriptomic similarities to human basal-like breast cancer.
Volume: 174
Issue: 1
Pages: 143-155
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23863842 | J:210404
First Author: Buckley NE
Year: 2013
Journal: Nucleic Acids Res
Title: BRCA1 is a key regulator of breast differentiation through activation of Notch signalling with implications for anti-endocrine treatment of breast cancers.
Volume: 41
Issue: 18
Pages: 8601-14
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34548335 | J:316877
First Author: Pulver EM
Year: 2021
Journal: Cancer Res
Title: A BRCA1 Coiled-Coil Domain Variant Disrupting PALB2 Interaction Promotes the Development of Mammary Tumors and Confers a Targetable Defect in Homologous Recombination Repair.
Volume: 81
Issue: 24
Pages: 6171-6182
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31877165 | J:283370
First Author: Park D
Year: 2019
Journal: PLoS One
Title: Murine models for familial pancreatic cancer: Histopathology, latency and drug sensitivity among cancers of Palb2, Brca1 and Brca2 mutant mouse strains.
Volume: 14
Issue: 12
Pages: e0226714
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12140760 | J:77948
First Author: Weaver Z
Year: 2002
Journal: Oncogene
Title: Mammary tumors in mice conditionally mutant for Brca1 exhibit gross genomic instability and centrosome amplification yet display a recurring distribution of genomic imbalances that is similar to human breast cancer.
Volume: 21
Issue: 33
Pages: 5097-107
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21396117 | J:175588
First Author: Burga LN
Year: 2011
Journal: Breast Cancer Res
Title: Loss of BRCA1 leads to an increase in epidermal growth factor receptor expression in mammary epithelial cells, and epidermal growth factor receptor inhibition prevents estrogen receptor-negative cancers in BRCA1-mutant mice.
Volume: 13
Issue: 2
Pages: R30
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16651405 | J:319986
First Author: Kim HS
Year: 2006
Journal: Cancer Res
Title: DNA damage-induced BARD1 phosphorylation is critical for the inhibition of messenger RNA processing by BRCA1/BARD1 complex.
Volume: 66
Issue: 9
Pages: 4561-5
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15159397 | J:319994
First Author: Fabbro M
Year: 2004
Journal: J Biol Chem
Title: BRCA1-BARD1 complexes are required for p53Ser-15 phosphorylation and a G1/S arrest following ionizing radiation-induced DNA damage.
Volume: 279
Issue: 30
Pages: 31251-8
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31916095 | J:299881
First Author: Stobezki R
Year: 2020
Journal: Reprod Sci
Title: Declining BRCA-Mediated DNA Repair in Sperm Aging and its Prevention by Sphingosine-1-Phosphate.
Volume: 27
Issue: 3
Pages: 940-953
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10881179 | J:63282
First Author: Mak TW
Year: 2000
Journal: Nat Immunol
Title: Brca1 required for T cell lineage development but not TCR loci rearrangement.
Volume: 1
Issue: 1
Pages: 77-82
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16108063 | J:101017
First Author: Henderson BR
Year: 2005
Journal: Bioessays
Title: Regulation of BRCA1, BRCA2 and BARD1 intracellular trafficking.
Volume: 27
Issue: 9
Pages: 884-93
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9798686 | J:50839
First Author: Ayi TC
Year: 1998
Journal: Oncogene
Title: Conservation of function and primary structure in the BRCA1-associated RING domain (BARD1) protein.
Volume: 17
Issue: 16
Pages: 2143-8
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Publication
16943438 | J:112308
First Author: Kim SS
Year: 2006
Journal: Mol Cell Biol
Title: Hyperplasia and spontaneous tumor development in the gynecologic system in mice lacking the BRCA1-Delta11 isoform.
Volume: 26
Issue: 18
Pages: 6983-92
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Publication
12485996 | J:320082
First Author: Mallery DL
Year: 2002
Journal: EMBO J
Title: Activation of the E3 ligase function of the BRCA1/BARD1 complex by polyubiquitin chains.
Volume: 21
Issue: 24
Pages: 6755-62
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28283467 | J:328028
First Author: Alothman SJ
Year: 2017
Journal: Cancer Prev Res (Phila)
Title: Responsiveness of Brca1 and Trp53 Deficiency-Induced Mammary Preneoplasia to Selective Estrogen Modulators versus an Aromatase Inhibitor in Mus musculus.
Volume: 10
Issue: 4
Pages: 244-254
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Publication
20656689 | J:320081
First Author: Patterson-Fortin J
Year: 2010
Journal: J Biol Chem
Title: Differential regulation of JAMM domain deubiquitinating enzyme activity within the RAP80 complex.
Volume: 285
Issue: 40
Pages: 30971-81
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Publication
24966277 | J:213861
First Author: Peng M
Year: 2014
Journal: EMBO J
Title: Crosstalk between BRCA-Fanconi anemia and mismatch repair pathways prevents MSH2-dependent aberrant DNA damage responses.
Volume: 33
Issue: 15
Pages: 1698-712
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Publication
30657944 | J:319683
First Author: Mohiuddin M
Year: 2019
Journal: Nucleic Acids Res
Title: CtIP-BRCA1 complex and MRE11 maintain replication forks in the presence of chain terminating nucleoside analogs.
Volume: 47
Issue: 6
Pages: 2966-2980
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Publication
18171670 | J:319979
First Author: Chen L
Year: 2008
Journal: J Biol Chem
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