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Search results 101 to 200 out of 1236 for Cdkn2a

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Type Details Score
Publication
17637672 | J:123407
First Author: Matheu A
Year: 2007
Journal: Nature
Title: Delayed ageing through damage protection by the Arf/p53 pathway.
Volume: 448
Issue: 7151
Pages: 375-9
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Publication
26728554 | J:227687
First Author: Shields BJ
Year: 2016
Journal: Genes Dev
Title: Acute myeloid leukemia requires Hhex to enable PRC2-mediated epigenetic repression of Cdkn2a.
Volume: 30
Issue: 1
Pages: 78-91
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Publication
33711247 | J:303711
First Author: Park J
Year: 2021
Journal: Dev Cell
Title: Progenitor-like characteristics in a subgroup of UCP1+ cells within white adipose tissue.
Volume: 56
Issue: 7
Pages: 985-999.e4
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Publication
20513429 | J:162926
First Author: Lessard F
Year: 2010
Journal: Mol Cell
Title: The ARF tumor suppressor controls ribosome biogenesis by regulating the RNA polymerase I transcription factor TTF-I.
Volume: 38
Issue: 4
Pages: 539-50
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Publication
22064482 | J:183671
First Author: Miceli AP
Year: 2012
Journal: Mol Cell Biol
Title: Hypergrowth mTORC1 signals translationally activate the ARF tumor suppressor checkpoint.
Volume: 32
Issue: 2
Pages: 348-64
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Publication
23029416 | J:192121
First Author: Eischen CM
Year: 2012
Journal: PLoS One
Title: Decreased Mdm2 expression inhibits tumor development and extends survival independent of Arf and dependent on p53.
Volume: 7
Issue: 9
Pages: e46148
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Publication
10541552 | J:58292
First Author: Eischen CM
Year: 1999
Journal: Genes Dev
Title: Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis.
Volume: 13
Issue: 20
Pages: 2658-69
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Publication
10995391 | J:64876
First Author: Weber JD
Year: 2000
Journal: Genes Dev
Title: p53-independent functions of the p19(ARF) tumor suppressor.
Volume: 14
Issue: 18
Pages: 2358-65
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Publication
16251190 | J:106797
First Author: Matheu A
Year: 2005
Journal: J Biol Chem
Title: Regulation of the INK4a/ARF locus by histone deacetylase inhibitors.
Volume: 280
Issue: 51
Pages: 42433-41
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Publication
23747016 | J:199251
First Author: Chen D
Year: 2013
Journal: Mol Cell
Title: Differential effects on ARF stability by normal versus oncogenic levels of c-Myc expression.
Volume: 51
Issue: 1
Pages: 46-56
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Publication
11818069 | J:73917
First Author: Tsai KY
Year: 2002
Journal: Curr Biol
Title: ARF is not required for apoptosis in Rb mutant mouse embryos.
Volume: 12
Issue: 2
Pages: 159-63
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Publication
11604501 | J:72281
First Author: Eischen CM
Year: 2001
Journal: Mol Cell Biol
Title: Bax loss impairs Myc-induced apoptosis and circumvents the selection of p53 mutations during Myc-mediated lymphomagenesis.
Volume: 21
Issue: 22
Pages: 7653-62
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Publication
15314658 | J:93298
First Author: Kelly-Spratt KS
Year: 2004
Journal: PLoS Biol
Title: p19Arf suppresses growth, progression, and metastasis of Hras-driven carcinomas through p53-dependent and -independent pathways.
Volume: 2
Issue: 8
Pages: E242
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Publication
22037868 | J:178844
First Author: Marshall AD
Year: 2011
Journal: Cancer Res
Title: PAX3-FOXO1 induces cannabinoid receptor 1 to enhance cell invasion and metastasis.
Volume: 71
Issue: 24
Pages: 7471-80
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Publication
26987019 | J:237183
   
First Author: Morena D
Year: 2016
Journal: Elife
Title: Hepatocyte Growth Factor-mediated satellite cells niche perturbation promotes development of distinct sarcoma subtypes.
Volume: 5
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Publication
32571801 | J:305083
 
First Author: Muralidharan SV
Year: 2020
Journal: Life Sci Alliance
Title: Small molecule inhibitors and a kinase-dead expressing mouse model demonstrate that the kinase activity of Chk1 is essential for mouse embryos and cancer cells.
Volume: 3
Issue: 8
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Publication
28490575 | J:247865
First Author: Jacobsen JA
Year: 2017
Journal: J Immunol
Title: EZH2 Regulates the Developmental Timing of Effectors of the Pre-Antigen Receptor Checkpoints.
Volume: 198
Issue: 12
Pages: 4682-4691
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Publication
23358651 | J:198243
First Author: Konstantinidou G
Year: 2013
Journal: Cancer Discov
Title: RHOA-FAK is a required signaling axis for the maintenance of KRAS-driven lung adenocarcinomas.
Volume: 3
Issue: 4
Pages: 444-57
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Publication
25117714 | J:214594
First Author: Ozawa T
Year: 2014
Journal: Cancer Cell
Title: Most human non-GCIMP glioblastoma subtypes evolve from a common proneural-like precursor glioma.
Volume: 26
Issue: 2
Pages: 288-300
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Publication
37169793 | J:335750
First Author: Wu R
Year: 2023
Journal: Nat Commun
Title: Genetically prolonged beige fat in male mice confers long-lasting metabolic health.
Volume: 14
Issue: 1
Pages: 2731
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Publication
24371224 | J:208166
First Author: Menges CW
Year: 2014
Journal: Cancer Res
Title: Tumor suppressor alterations cooperate to drive aggressive mesotheliomas with enriched cancer stem cells via a p53-miR-34a-c-Met axis.
Volume: 74
Issue: 4
Pages: 1261-1271
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Publication
23685457 | J:201011
First Author: Moreno-Asso A
Year: 2013
Journal: Diabetologia
Title: Glucose regulation of a cell cycle gene module is selectively lost in mouse pancreatic islets during ageing.
Volume: 56
Issue: 8
Pages: 1761-72
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Publication
12185367 | J:78529
First Author: Lund AH
Year: 2002
Journal: Nat Genet
Title: Genome-wide retroviral insertional tagging of genes involved in cancer in Cdkn2a-deficient mice.
Volume: 32
Issue: 1
Pages: 160-5
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Publication
26239104 | J:308754
First Author: An S
Year: 2015
Journal: Mol Med Rep
Title: Inactivation of INK4a and ARF induces myocardial proliferation and improves cardiac repair following ischemia‑reperfusion.
Volume: 12
Issue: 4
Pages: 5911-6
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Publication
22403661 | J:186851
First Author: Wouters K
Year: 2012
Journal: PLoS One
Title: Bone marrow p16INK4a-deficiency does not modulate obesity, glucose homeostasis or atherosclerosis development.
Volume: 7
Issue: 3
Pages: e32440
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Publication
11113205 | J:67572
First Author: Zhang SL
Year: 2001
Journal: Mol Cell Biol
Title: Efficiency alleles of the Pctr1 modifier locus for plasmacytoma susceptibility.
Volume: 21
Issue: 1
Pages: 310-8
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23467612 | J:197052
First Author: Lin WC
Year: 2013
Journal: Cancer Res
Title: Dormant cancer cells contribute to residual disease in a model of reversible pancreatic cancer.
Volume: 73
Issue: 6
Pages: 1821-30
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Publication
28418604 | J:271880
First Author: Ahmad I
Year: 2017
Journal: Exp Dermatol
Title: Loss of INK4a/Arf gene enhances ultraviolet radiation-induced cutaneous tumor development.
Volume: 26
Issue: 11
Pages: 1018-1025
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Publication
11544530 | J:71393
First Author: Krimpenfort P
Year: 2001
Journal: Nature
Title: Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice.
Volume: 413
Issue: 6851
Pages: 83-6
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Publication
33037071 | J:299412
First Author: Deleye Y
Year: 2020
Journal: J Biol Chem
Title: CDKN2A/p16INK4a suppresses hepatic fatty acid oxidation through the AMPKα2-SIRT1-PPARα signaling pathway.
Volume: 295
Issue: 50
Pages: 17310-17322
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Publication
21636855 | J:176942
First Author: Cudejko C
Year: 2011
Journal: Blood
Title: p16INK4a deficiency promotes IL-4-induced polarization and inhibits proinflammatory signaling in macrophages.
Volume: 118
Issue: 9
Pages: 2556-66
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Publication
34439790 | J:337776
 
First Author: Montano E
Year: 2021
Journal: Biomolecules
Title: Pancreatic Progenitor Commitment Is Marked by an Increase in Ink4a/Arf Expression.
Volume: 11
Issue: 8
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Publication
20381282 | J:170042
First Author: González-Navarro H
Year: 2010
Journal: J Am Coll Cardiol
Title: p19(ARF) deficiency reduces macrophage and vascular smooth muscle cell apoptosis and aggravates atherosclerosis.
Volume: 55
Issue: 20
Pages: 2258-68
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Publication
30684556 | J:294488
First Author: Saito M
Year: 2019
Journal: J Invest Dermatol
Title: A Polymorphic Variant in p19Arf Confers Resistance to Chemically Induced Skin Tumors by Activating the p53 Pathway.
Volume: 139
Issue: 7
Pages: 1459-1469
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Publication
32317048 | J:313288
First Author: Strauss RP
Year: 2020
Journal: Gene Expr
Title: Loss of ARF/INK4A Promotes Liver Progenitor Cell Transformation Toward Tumorigenicity Supporting Their Role in Hepatocarcinogenesis.
Volume: 20
Issue: 1
Pages: 39-52
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Publication
11438662 | J:70387
First Author: Eischen CM
Year: 2001
Journal: Mol Cell Biol
Title: Apoptosis triggered by Myc-induced suppression of Bcl-X(L) or Bcl-2 is bypassed during lymphomagenesis.
Volume: 21
Issue: 15
Pages: 5063-70
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Publication
17974917 | J:126308
First Author: Bouchard C
Year: 2007
Journal: Genes Dev
Title: FoxO transcription factors suppress Myc-driven lymphomagenesis via direct activation of Arf.
Volume: 21
Issue: 21
Pages: 2775-87
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21400497 | J:177016
First Author: Guo Y
Year: 2011
Journal: Eur J Immunol
Title: Polycomb group gene Bmi1 plays a role in the growth of thymic epithelial cells.
Volume: 41
Issue: 4
Pages: 1098-107
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Publication
18485879 | J:136338
First Author: Uren AG
Year: 2008
Journal: Cell
Title: Large-scale mutagenesis in p19(ARF)- and p53-deficient mice identifies cancer genes and their collaborative networks.
Volume: 133
Issue: 4
Pages: 727-41
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Publication
18060046 | J:130828
First Author: Debies MT
Year: 2008
Journal: J Clin Invest
Title: Tumor escape in a Wnt1-dependent mouse breast cancer model is enabled by p19Arf/p53 pathway lesions but not p16 Ink4a loss.
Volume: 118
Issue: 1
Pages: 51-63
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Publication
16407836 | J:108774
First Author: Shank-Calvo JA
Year: 2006
Journal: Oncogene
Title: p16Ink4a or p19Arf loss contributes to Tal1-induced leukemogenesis in mice.
Volume: 25
Issue: 21
Pages: 3023-31
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Publication
28092679 | J:243507
First Author: Tonelli C
Year: 2017
Journal: Oncogene
Title: Genome-wide analysis of p53-regulated transcription in Myc-driven lymphomas.
Volume: 36
Issue: 21
Pages: 2921-2929
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Publication
16037818 | J:101016
First Author: Silva RL
Year: 2005
Journal: EMBO J
Title: Arf-dependent regulation of Pdgf signaling in perivascular cells in the developing mouse eye.
Volume: 24
Issue: 15
Pages: 2803-14
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Publication
25823025 | J:332564
First Author: Meng X
Year: 2015
Journal: Oncogene
Title: Oncogenic c-Myc-induced lymphomagenesis is inhibited non-redundantly by the p19Arf-Mdm2-p53 and RP-Mdm2-p53 pathways.
Volume: 34
Issue: 46
Pages: 5709-17
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Publication
14991053 | J:121570
First Author: Bulavin DV
Year: 2004
Journal: Nat Genet
Title: Inactivation of the Wip1 phosphatase inhibits mammary tumorigenesis through p38 MAPK-mediated activation of the p16(Ink4a)-p19(Arf) pathway.
Volume: 36
Issue: 4
Pages: 343-50
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Publication
26526724 | J:324279
First Author: Chiacchiera F
Year: 2016
Journal: Cell Stem Cell
Title: Polycomb Complex PRC1 Preserves Intestinal Stem Cell Identity by Sustaining Wnt/β-Catenin Transcriptional Activity.
Volume: 18
Issue: 1
Pages: 91-103
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Publication
26592448 | J:228015
First Author: Diersch S
Year: 2016
Journal: Oncogene
Title: Kras(G12D) induces EGFR-MYC cross signaling in murine primary pancreatic ductal epithelial cells.
Volume: 35
Issue: 29
Pages: 3880-6
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Publication
25584893 | J:218894
First Author: Damsky W
Year: 2015
Journal: Cancer Cell
Title: mTORC1 activation blocks BrafV600E-induced growth arrest but is insufficient for melanoma formation.
Volume: 27
Issue: 1
Pages: 41-56
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Publication
30575739 | J:270170
First Author: Li F
Year: 2018
Journal: Nat Commun
Title: Ezh2 programs TFH differentiation by integrating phosphorylation-dependent activation of Bcl6 and polycomb-dependent repression of p19Arf.
Volume: 9
Issue: 1
Pages: 5452
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Publication
26118502 | J:230773
First Author: Danis E
Year: 2015
Journal: Exp Hematol
Title: Inactivation of Eed impedes MLL-AF9-mediated leukemogenesis through Cdkn2a-dependent and Cdkn2a-independent mechanisms in a murine model.
Volume: 43
Issue: 11
Pages: 930-935.e6
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Publication
35311644 | J:349119
   
First Author: Reinitz F
Year: 2022
Journal: Elife
Title: Inhibiting USP16 rescues stem cell aging and memory in an Alzheimer's model.
Volume: 11
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Publication
24618618 | J:211558
First Author: Schuster K
Year: 2014
Journal: Mol Cancer Res
Title: Nullifying the CDKN2AB locus promotes mutant K-ras lung tumorigenesis.
Volume: 12
Issue: 6
Pages: 912-23
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9501299 | J:46281
First Author: Malumbres M
Year: 1998
Journal: Mamm Genome
Title: An AC-repeat adjacent to mouse Cdkn2B allows the detection of specific allelic losses in the p15INK4b and p16INK4a tumor suppressor genes.
Volume: 9
Issue: 3
Pages: 183-5
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21949886 | J:177670
First Author: Põlajeva J
Year: 2011
Journal: PLoS One
Title: Mast cell accumulation in glioblastoma with a potential role for stem cell factor and chemokine CXCL12.
Volume: 6
Issue: 9
Pages: e25222
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20144787 | J:157069
First Author: Charles N
Year: 2010
Journal: Cell Stem Cell
Title: Perivascular nitric oxide activates notch signaling and promotes stem-like character in PDGF-induced glioma cells.
Volume: 6
Issue: 2
Pages: 141-52
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Publication
15781613 | J:97154
First Author: Uhrbom L
Year: 2005
Journal: Cancer Res
Title: Cell type-specific tumor suppression by Ink4a and Arf in Kras-induced mouse gliomagenesis.
Volume: 65
Issue: 6
Pages: 2065-9
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Publication
21518927 | J:174824
First Author: Martinelli P
Year: 2011
Journal: Blood
Title: The lymphoma-associated NPM-ALK oncogene elicits a p16INK4a/pRb-dependent tumor-suppressive pathway.
Volume: 117
Issue: 24
Pages: 6617-26
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Publication
36869047 | J:333935
First Author: Mainwaring OJ
Year: 2023
Journal: Nat Commun
Title: ARF suppression by MYC but not MYCN confers increased malignancy of aggressive pediatric brain tumors.
Volume: 14
Issue: 1
Pages: 1221
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Publication
32485135 | J:296551
First Author: Grosse L
Year: 2020
Journal: Cell Metab
Title: Defined p16High Senescent Cell Types Are Indispensable for Mouse Healthspan.
Volume: 32
Issue: 1
Pages: 87-99.e6
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32949498 | J:300221
First Author: Omori S
Year: 2020
Journal: Cell Metab
Title: Generation of a p16 Reporter Mouse and Its Use to Characterize and Target p16high Cells In Vivo.
Volume: 32
Issue: 5
Pages: 814-828.e6
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28122246 | J:254513
First Author: Jiang Y
Year: 2017
Journal: Cell Rep
Title: Glioblastoma Cell Malignancy and Drug Sensitivity Are Affected by the Cell of Origin.
Volume: 18
Issue: 4
Pages: 977-990
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20639864 | J:163931
First Author: Johnson RA
Year: 2010
Journal: Nature
Title: Cross-species genomics matches driver mutations and cell compartments to model ependymoma.
Volume: 466
Issue: 7306
Pages: 632-6
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12185599 | J:78497
First Author: Zhang Z
Year: 2002
Journal: Oncogene
Title: A strong candidate gene for the Papg1 locus on mouse chromosome 4 affecting lung tumor progression.
Volume: 21
Issue: 38
Pages: 5960-6
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26446488 | J:227643
 
First Author: Liu XS
Year: 2015
Journal: Nat Commun
Title: LRF maintains genome integrity by regulating the non-homologous end joining pathway of DNA repair.
Volume: 6
Pages: 8325
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Publication
12486224 | J:81016
First Author: Tsai KY
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: ARF mutation accelerates pituitary tumor development in Rb+/- mice.
Volume: 99
Issue: 26
Pages: 16865-70
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26965367 | J:235536
First Author: Barabino A
Year: 2016
Journal: Development
Title: Loss of Bmi1 causes anomalies in retinal development and degeneration of cone photoreceptors.
Volume: 143
Issue: 9
Pages: 1571-84
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15175242 | J:90855
First Author: Aslanian A
Year: 2004
Journal: Genes Dev
Title: Repression of the Arf tumor suppressor by E2F3 is required for normal cell cycle kinetics.
Volume: 18
Issue: 12
Pages: 1413-22
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Publication
21209895 | J:168312
First Author: Rauch DA
Year: 2010
Journal: PLoS One
Title: The ARF tumor suppressor regulates bone remodeling and osteosarcoma development in mice.
Volume: 5
Issue: 12
Pages: e15755
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14673154 | J:87594
First Author: O'Leary KA
Year: 2004
Journal: Mol Cell Biol
Title: Mdm2 regulates p53 independently of p19(ARF) in homeostatic tissues.
Volume: 24
Issue: 1
Pages: 186-91
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15589172 | J:94683
First Author: Iwama A
Year: 2004
Journal: Immunity
Title: Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1.
Volume: 21
Issue: 6
Pages: 843-51
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Publication
19690330 | J:260259
First Author: Chen Z
Year: 2009
Journal: Sci Signal
Title: Differential p53-independent outcomes of p19(Arf) loss in oncogenesis.
Volume: 2
Issue: 84
Pages: ra44
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20197621 | J:158734
First Author: Alimonti A
Year: 2010
Journal: J Clin Invest
Title: A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis.
Volume: 120
Issue: 3
Pages: 681-93
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28263978 | J:243369
First Author: Wang GY
Year: 2017
Journal: Oncogene
Title: Differing tumor-suppressor functions of Arf and p53 in murine basal cell carcinoma initiation and progression.
Volume: 36
Issue: 26
Pages: 3772-3780
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25622904 | J:244951
First Author: Tan M
Year: 2015
Journal: Neoplasia
Title: Inactivation of Sag/Rbx2/Roc2 e3 ubiquitin ligase triggers senescence and inhibits kras-induced immortalization.
Volume: 17
Issue: 1
Pages: 114-23
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28949402 | J:283471
First Author: Zhao L
Year: 2018
Journal: Mol Carcinog
Title: Gain of function in the mouse model of a recurrent mutation p53N236S promotes the formation of double minute chromosomes and the oncogenic potential of p19ARF.
Volume: 57
Issue: 2
Pages: 147-158
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Publication
35150661 | J:323002
     
First Author: Lazar I
Year: 2022
Journal: J Invest Dermatol
Title: Adipocyte Extracellular Vesicles Decrease p16INK4A in Melanoma: An Additional Link between Obesity and Cancer.
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19398955 | J:151455
First Author: Goel VK
Year: 2009
Journal: Oncogene
Title: Melanocytic nevus-like hyperplasia and melanoma in transgenic BRAFV600E mice.
Volume: 28
Issue: 23
Pages: 2289-98
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28577303 | J:253445
First Author: Jackson JT
Year: 2017
Journal: Stem Cells
Title: Hhex Regulates Hematopoietic Stem Cell Self-Renewal and Stress Hematopoiesis via Repression of Cdkn2a.
Volume: 35
Issue: 8
Pages: 1948-1957
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Publication
22860046 | J:189678
First Author: Winkeler CL
Year: 2012
Journal: PLoS One
Title: Cathepsin K-Cre causes unexpected germline deletion of genes in mice.
Volume: 7
Issue: 7
Pages: e42005
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Publication
22048312 | J:178299
First Author: Baker DJ
Year: 2011
Journal: Nature
Title: Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders.
Volume: 479
Issue: 7372
Pages: 232-6
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Publication
21804542 | J:241062
First Author: Sasaki M
Year: 2011
Journal: Nat Med
Title: Regulation of the MDM2-P53 pathway and tumor growth by PICT1 via nucleolar RPL11.
Volume: 17
Issue: 8
Pages: 944-51
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17728759 | J:125164
First Author: Gorrini C
Year: 2007
Journal: Nature
Title: Tip60 is a haplo-insufficient tumour suppressor required for an oncogene-induced DNA damage response.
Volume: 448
Issue: 7157
Pages: 1063-7
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Publication
16222716 | J:102855
First Author: Jerome-Majewska LA
Year: 2005
Journal: Dev Dyn
Title: Tbx3, the ulnar-mammary syndrome gene, and Tbx2 interact in mammary gland development through a p19Arf/p53-independent pathway.
Volume: 234
Issue: 4
Pages: 922-33
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Publication
11212243 | J:67452
First Author: Wetmore C
Year: 2001
Journal: Cancer Res
Title: Loss of p53 but not ARF accelerates medulloblastoma in mice heterozygous for patched.
Volume: 61
Issue: 2
Pages: 513-6
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Publication
12082524 | J:126187
First Author: Palmero I
Year: 2002
Journal: Oncogene
Title: Activation of ARF by oncogenic stress in mouse fibroblasts is independent of E2F1 and E2F2.
Volume: 21
Issue: 19
Pages: 2939-47
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