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Search results 101 to 192 out of 192 for Cyp7a1

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Category: Publication
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Type Details Score
Publication
11788471 | J:118722
First Author: Miyake JH
Year: 2002
Journal: Arterioscler Thromb Vasc Biol
Title: Transgenic expression of cholesterol-7-alpha-hydroxylase prevents atherosclerosis in C57BL/6J mice.
Volume: 22
Issue: 1
Pages: 121-6
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Publication
26997483 | J:234411
First Author: Okin D
Year: 2016
Journal: Cell
Title: The Effect of Sustained Inflammation on Hepatic Mevalonate Pathway Results in Hyperglycemia.
Volume: 165
Issue: 2
Pages: 343-56
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Publication
16284190 | J:118817
First Author: Gutierrez A
Year: 2006
Journal: Arterioscler Thromb Vasc Biol
Title: Bile acids decrease hepatic paraoxonase 1 expression and plasma high-density lipoprotein levels via FXR-mediated signaling of FGFR4.
Volume: 26
Issue: 2
Pages: 301-6
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Publication
20456485 | J:308408
First Author: Wang HH
Year: 2010
Journal: Eur J Clin Invest
Title: Transgenic overexpression of Abcb11 enhances biliary bile salt outputs, but does not affect cholesterol cholelithogenesis in mice.
Volume: 40
Issue: 6
Pages: 541-51
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Publication
15650132 | J:128561
First Author: Sundaram SS
Year: 2005
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Steatohepatitis develops rapidly in transgenic mice overexpressing Abcb11 and fed a methionine-choline-deficient diet.
Volume: 288
Issue: 6
Pages: G1321-7
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Publication
16341669 | J:104062
First Author: Henkel A
Year: 2005
Journal: Mamm Genome
Title: Mice overexpressing hepatic Abcb11 rapidly develop cholesterol gallstones.
Volume: 16
Issue: 12
Pages: 903-8
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Publication
14570929 | J:94496
First Author: Figge A
Year: 2004
Journal: J Biol Chem
Title: Hepatic overexpression of murine Abcb11 increases hepatobiliary lipid secretion and reduces hepatic steatosis.
Volume: 279
Issue: 4
Pages: 2790-9
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Publication
16213224 | J:129677
First Author: Inagaki T
Year: 2005
Journal: Cell Metab
Title: Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis.
Volume: 2
Issue: 4
Pages: 217-25
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Publication
37696161 | J:341197
First Author: Zhou C
Year: 2023
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Fibroblast growth factor 21 ameliorates cholestatic liver injury via a hepatic FGFR4-JNK pathway.
Volume: 1870
Issue: 1
Pages: 166870
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Publication
26615883 | J:274085
 
First Author: Lee EY
Year: 2015
Journal: Sci Rep
Title: Unsuppressed lipolysis in adipocytes is linked with enhanced gluconeogenesis and altered bile acid physiology in Insr(P1195L/+) mice fed high-fat-diet.
Volume: 5
Pages: 17565
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Publication
16516849 | J:107072
First Author: Wang J
Year: 2006
Journal: Biochem Biophys Res Commun
Title: Critical role of cholic acid for development of hypercholesterolemia and gallstones in diabetic mice.
Volume: 342
Issue: 4
Pages: 1382-8
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Publication
12062084 | J:102129
First Author: Kerr TA
Year: 2002
Journal: Dev Cell
Title: Loss of nuclear receptor SHP impairs but does not eliminate negative feedback regulation of bile acid synthesis.
Volume: 2
Issue: 6
Pages: 713-20
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Publication
19956992 | J:289377
First Author: Pirinen E
Year: 2010
Journal: Amino Acids
Title: Activated polyamine catabolism leads to low cholesterol levels by enhancing bile acid synthesis.
Volume: 38
Issue: 2
Pages: 549-60
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Publication
11030332 | J:64755
First Author: Goodwin B
Year: 2000
Journal: Mol Cell
Title: A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis.
Volume: 6
Issue: 3
Pages: 517-26
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Publication
30745141 | J:272595
First Author: Ji S
Year: 2019
Journal: Dev Cell
Title: FGF15 Activates Hippo Signaling to Suppress Bile Acid Metabolism and Liver Tumorigenesis.
Volume: 48
Issue: 4
Pages: 460-474.e9
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Publication
28041926 | J:278381
 
First Author: Zhang J
Year: 2017
Journal: EBioMedicine
Title: Chronic Over-expression of Fibroblast Growth Factor 21 Increases Bile Acid Biosynthesis by Opposing FGF15/19 Action.
Volume: 15
Pages: 173-183
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Publication
38613835 | J:360206
First Author: Huang S
Year: 2024
Journal: Adv Sci (Weinh)
Title: Osteocytes/Osteoblasts Produce SAA3 to Regulate Hepatic Metabolism of Cholesterol.
Volume: 11
Issue: 24
Pages: e2307818
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Publication
18292224 | J:132778
First Author: Rao A
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: The organic solute transporter alpha-beta, Ostalpha-Ostbeta, is essential for intestinal bile acid transport and homeostasis.
Volume: 105
Issue: 10
Pages: 3891-6
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Publication
19805516 | J:154989
First Author: Miao J
Year: 2009
Journal: Mol Cell Biol
Title: Functional specificities of Brm and Brg-1 Swi/Snf ATPases in the feedback regulation of hepatic bile acid biosynthesis.
Volume: 29
Issue: 23
Pages: 6170-81
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Publication
19237543 | J:149773
First Author: Shin DJ
Year: 2009
Journal: J Biol Chem
Title: FGF15/FGFR4 integrates growth factor signaling with hepatic bile acid metabolism and insulin action.
Volume: 284
Issue: 17
Pages: 11110-20
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Publication
16075061 | J:100209
First Author: Ito S
Year: 2005
Journal: J Clin Invest
Title: Impaired negative feedback suppression of bile acid synthesis in mice lacking betaKlotho.
Volume: 115
Issue: 8
Pages: 2202-8
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Publication
18565334 | J:141770
First Author: Duez H
Year: 2008
Journal: Gastroenterology
Title: Regulation of bile acid synthesis by the nuclear receptor Rev-erbalpha.
Volume: 135
Issue: 2
Pages: 689-98
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Publication
30127091 | J:266457
First Author: Hansen AMK
Year: 2018
Journal: Biochem J
Title: Differential receptor selectivity of the FGF15/FGF19 orthologues determines distinct metabolic activities in db/db mice.
Volume: 475
Issue: 18
Pages: 2985-2996
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Publication
30464200 | J:269976
First Author: Gadaleta RM
Year: 2018
Journal: Sci Rep
Title: Suppression of Hepatic Bile Acid Synthesis by a non-tumorigenic FGF19 analogue Protects Mice from Fibrosis and Hepatocarcinogenesis.
Volume: 8
Issue: 1
Pages: 17210
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Publication
19706524 | J:151994
First Author: Wu X
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Selective activation of FGFR4 by an FGF19 variant does not improve glucose metabolism in ob/ob mice.
Volume: 106
Issue: 34
Pages: 14379-84
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Publication
29191818 | J:277988
 
First Author: Zurkinden L
Year: 2018
Journal: Biosci Rep
Title: Sterol 27-hydroxylase gene dosage and the antiatherosclerotic effect of Rifampicin in mice.
Volume: 38
Issue: 1
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Publication
26890232 | J:276667
First Author: Matziouridou C
Year: 2016
Journal: Mol Nutr Food Res
Title: Lingonberries reduce atherosclerosis in Apoe(-/-) mice in association with altered gut microbiota composition and improved lipid profile.
Volume: 60
Issue: 5
Pages: 1150-60
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Publication
18820241 | J:149005
First Author: Hartman HB
Year: 2009
Journal: J Lipid Res
Title: Loss of small heterodimer partner expression in the liver protects against dyslipidemia.
Volume: 50
Issue: 2
Pages: 193-203
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Publication
23087171 | J:192628
First Author: Lin JZ
Year: 2012
Journal: Endocrinology
Title: Thyroid hormone receptor agonists reduce serum cholesterol independent of the LDL receptor.
Volume: 153
Issue: 12
Pages: 6136-44
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Publication
22185956 | J:182449
First Author: Gessner DK
Year: 2012
Journal: Biochim Biophys Acta
Title: Increased plasma thyroid hormone concentrations in LDL receptor deficient mice may be explained by inhibition of aryl hydrocarbon receptor-dependent expression of hepatic UDP-glucuronosyltransferases.
Volume: 1820
Issue: 4
Pages: 495-502
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Publication
27895309 | J:298387
First Author: Lemberger UJ
Year: 2016
Journal: Oncotarget
Title: Hepatocyte specific expression of an oncogenic variant of β-catenin results in cholestatic liver disease.
Volume: 7
Issue: 52
Pages: 86985-86998
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Publication
16260782 | J:105670
First Author: Hashimoto K
Year: 2006
Journal: J Biol Chem
Title: Cross-talk between thyroid hormone receptor and liver X receptor regulatory pathways is revealed in a thyroid hormone resistance mouse model.
Volume: 281
Issue: 1
Pages: 295-302
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Publication
17971517 | J:131221
First Author: Kudo T
Year: 2008
Journal: Am J Physiol Endocrinol Metab
Title: Clock mutation facilitates accumulation of cholesterol in the liver of mice fed a cholesterol and/or cholic acid diet.
Volume: 294
Issue: 1
Pages: E120-30
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Publication
28754826 | J:248490
First Author: Nuñez-Garcia M
Year: 2017
Journal: J Lipid Res
Title: Osteopontin regulates the cross-talk between phosphatidylcholine and cholesterol metabolism in mouse liver.
Volume: 58
Issue: 9
Pages: 1903-1915
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Publication
27484115 | J:322880
 
First Author: Lin J
Year: 2016
Journal: Sci Rep
Title: Osteopontin Deficiency Alters Biliary Homeostasis and Protects against Gallstone Formation.
Volume: 6
Pages: 30215
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Publication
19718444 | J:152389
First Author: Ma K
Year: 2009
Journal: PLoS One
Title: Circadian dysregulation disrupts bile acid homeostasis.
Volume: 4
Issue: 8
Pages: e6843
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Publication
22467244 | J:293604
First Author: Kong B
Year: 2012
Journal: Hepatology
Title: Mechanism of tissue-specific farnesoid X receptor in suppressing the expression of genes in bile-acid synthesis in mice.
Volume: 56
Issue: 3
Pages: 1034-43
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Publication
24421394 | J:213532
First Author: Ramakrishnan SK
Year: 2014
Journal: Mol Cell Biol
Title: Loss of von Hippel-Lindau protein (VHL) increases systemic cholesterol levels through targeting hypoxia-inducible factor 2α and regulation of bile acid homeostasis.
Volume: 34
Issue: 7
Pages: 1208-20
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Publication
30803859 | J:291563
First Author: Kong B
Year: 2019
Journal: Dig Liver Dis
Title: FXR deficiency alters bile acid pool composition and exacerbates chronic alcohol induced liver injury.
Volume: 51
Issue: 4
Pages: 570-576
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Publication
28891815 | J:247719
First Author: Tarling EJ
Year: 2017
Journal: J Clin Invest
Title: RNA-binding protein ZFP36L1 maintains posttranscriptional regulation of bile acid metabolism.
Volume: 127
Issue: 10
Pages: 3741-3754
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Publication
20233723 | J:164561
First Author: Schmidt DR
Year: 2010
Journal: J Biol Chem
Title: Regulation of bile acid synthesis by fat-soluble vitamins A and D.
Volume: 285
Issue: 19
Pages: 14486-94
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Publication
18988759 | J:163803
First Author: Miyata M
Year: 2009
Journal: Drug Metab Dispos
Title: Cholesterol feeding prevents hepatic accumulation of bile acids in cholic acid-fed farnesoid X receptor (FXR)-null mice: FXR-independent suppression of intestinal bile acid absorption.
Volume: 37
Issue: 2
Pages: 338-44
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Publication
22542490 | J:320452
First Author: Lan T
Year: 2012
Journal: J Hepatol
Title: Mouse organic solute transporter alpha deficiency alters FGF15 expression and bile acid metabolism.
Volume: 57
Issue: 2
Pages: 359-65
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Publication
17720959 | J:129978
First Author: Kim I
Year: 2007
Journal: J Lipid Res
Title: Differential regulation of bile acid homeostasis by the farnesoid X receptor in liver and intestine.
Volume: 48
Issue: 12
Pages: 2664-72
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Publication
17908797 | J:129067
First Author: Li Q
Year: 2007
Journal: Mol Cell Biol
Title: Tissue- and nuclear receptor-specific function of the C-terminal LXXLL motif of coactivator NCoA6/AIB3 in mice.
Volume: 27
Issue: 23
Pages: 8073-86
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Publication
15717863 | J:104503
First Author: Wang XJ
Year: 2005
Journal: Biochem J
Title: Relationship between hepatic phenotype and changes in gene expression in cytochrome P450 reductase (POR) null mice.
Volume: 388
Issue: Pt 3
Pages: 857-67
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Publication
26372644 | J:243180
First Author: Fu ZD
Year: 2015
Journal: PLoS One
Title: The Role of Sirt1 in Bile Acid Regulation during Calorie Restriction in Mice.
Volume: 10
Issue: 9
Pages: e0138307
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Publication
18323469 | J:135822
First Author: Lee YK
Year: 2008
Journal: Mol Endocrinol
Title: Liver receptor homolog-1 regulates bile acid homeostasis but is not essential for feedback regulation of bile acid synthesis.
Volume: 22
Issue: 6
Pages: 1345-56
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Publication
24755711 | J:215174
First Author: Lou G
Year: 2014
Journal: PLoS One
Title: GPBAR1/TGR5 mediates bile acid-induced cytokine expression in murine Kupffer cells.
Volume: 9
Issue: 4
Pages: e93567
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Publication
22345550 | J:187491
First Author: Weerachayaphorn J
Year: 2012
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Nuclear factor-E2-related factor 2 is a major determinant of bile acid homeostasis in the liver and intestine.
Volume: 302
Issue: 9
Pages: G925-36
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Publication
23710285 | J:318023
 
First Author: Chartoumpekis DV
Year: 2013
Journal: Oxid Med Cell Longev
Title: Hepatic gene expression profiling in Nrf2 knockout mice after long-term high-fat diet-induced obesity.
Volume: 2013
Pages: 340731
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Publication
24704458 | J:212463
First Author: Takahashi K
Year: 2014
Journal: Biochim Biophys Acta
Title: Ascorbic acid deficiency affects genes for oxidation-reduction and lipid metabolism in livers from SMP30/GNL knockout mice.
Volume: 1840
Issue: 7
Pages: 2289-98
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Publication
19136665 | J:149641
First Author: Xie Y
Year: 2009
Journal: J Lipid Res
Title: Increased susceptibility to diet-induced gallstones in liver fatty acid binding protein knockout mice.
Volume: 50
Issue: 5
Pages: 977-87
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17761942 | J:135003
First Author: Heverin M
Year: 2007
Journal: Arterioscler Thromb Vasc Biol
Title: Studies on the cholesterol-free mouse: strong activation of LXR-regulated hepatic genes when replacing cholesterol with desmosterol.
Volume: 27
Issue: 10
Pages: 2191-7
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Publication
34936222 | J:345067
First Author: Cingolani F
Year: 2022
Journal: Hepatol Commun
Title: Redundant Functions of ERK1 and ERK2 Maintain Mouse Liver Homeostasis Through Down-Regulation of Bile Acid Synthesis.
Volume: 6
Issue: 5
Pages: 980-994
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Publication
23614904 | J:200728
First Author: Parker RA
Year: 2013
Journal: J Lipid Res
Title: Bile acid and sterol metabolism with combined HMG-CoA reductase and PCSK9 suppression.
Volume: 54
Issue: 9
Pages: 2400-9
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Publication
16264196 | J:107562
First Author: Wang J
Year: 2006
Journal: J Lipid Res
Title: Studies on LXR- and FXR-mediated effects on cholesterol homeostasis in normal and cholic acid-depleted mice.
Volume: 47
Issue: 2
Pages: 421-30
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11602523 | J:103235
First Author: Staudinger J
Year: 2001
Journal: Drug Metab Dispos
Title: Coordinate regulation of xenobiotic and bile acid homeostasis by pregnane X receptor.
Volume: 29
Issue: 11
Pages: 1467-72
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Publication
35657825 | J:328526
First Author: Lynch EC
Year: 2022
Journal: PLoS One
Title: Disrupting Osr1 expression promoted hepatic steatosis and inflammation induced by high-fat diet in the mouse model.
Volume: 17
Issue: 6
Pages: e0268344
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Publication
18497332 | J:137523
First Author: Ballatori N
Year: 2008
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Ostalpha-Ostbeta is required for bile acid and conjugated steroid disposition in the intestine, kidney, and liver.
Volume: 295
Issue: 1
Pages: G179-G186
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Publication
25361754 | J:223083
 
First Author: Helmering J
Year: 2014
Journal: Lipids Health Dis
Title: A mutation in Ampd2 is associated with nephrotic syndrome and hypercholesterolemia in mice.
Volume: 13
Pages: 167
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22981383 | J:291260
First Author: Kim EH
Year: 2012
Journal: Biochem Pharmacol
Title: Endogenously synthesized n-3 polyunsaturated fatty acids in fat-1 mice ameliorate high-fat diet-induced non-alcoholic fatty liver disease.
Volume: 84
Issue: 10
Pages: 1359-65
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Publication
20375098 | J:173433
First Author: Chanda D
Year: 2010
Journal: Nucleic Acids Res
Title: Transcriptional corepressor SHP recruits SIRT1 histone deacetylase to inhibit LRH-1 transactivation.
Volume: 38
Issue: 14
Pages: 4607-19
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14592954 | J:96326
First Author: Drover VA
Year: 2004
Journal: Endocrinology
Title: Regulation of the human cholesterol 7alpha-hydroxylase gene (CYP7A1) by thyroid hormone in transgenic mice.
Volume: 145
Issue: 2
Pages: 574-81
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20371703 | J:162260
First Author: Han S
Year: 2010
Journal: Mol Endocrinol
Title: A novel bile acid-activated vitamin D receptor signaling in human hepatocytes.
Volume: 24
Issue: 6
Pages: 1151-64
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21933665 | J:180709
First Author: Buler M
Year: 2011
Journal: Biochem Pharmacol
Title: Energy sensing factors PGC-1α and SIRT1 modulate PXR expression and function.
Volume: 82
Issue: 12
Pages: 2008-15
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Publication
23139217 | J:194692
First Author: Henkel AS
Year: 2013
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Hepatic overexpression of Abcb11 in mice promotes the conservation of bile acids within the enterohepatic circulation.
Volume: 304
Issue: 2
Pages: G221-6
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Publication
25080475 | J:215780
First Author: Luo J
Year: 2014
Journal: Sci Transl Med
Title: A nontumorigenic variant of FGF19 treats cholestatic liver diseases.
Volume: 6
Issue: 247
Pages: 247ra100
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27207555 | J:246238
First Author: Elias I
Year: 2016
Journal: Diabetes
Title: ALOX5AP Overexpression in Adipose Tissue Leads to LXA4 Production and Protection Against Diet-Induced Obesity and Insulin Resistance.
Volume: 65
Issue: 8
Pages: 2139-50
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Publication
27394190 | J:249060
 
First Author: Athanason MG
Year: 2016
Journal: Mol Cell Endocrinol
Title: Quantitative proteomic profiling reveals hepatic lipogenesis and liver X receptor activation in the PANDER transgenic model.
Volume: 436
Pages: 41-9
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Publication
25056539 | J:319133
First Author: Wang C
Year: 2014
Journal: Curr Mol Med
Title: Hepatocyte FRS2α is essential for the endocrine fibroblast growth factor to limit the amplitude of bile acid production induced by prandial activity.
Volume: 14
Issue: 6
Pages: 703-711
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Publication
35451003 | J:341886
 
First Author: Shaw RPH
Year: 2022
Journal: Endocrinology
Title: Loss of Hepatic Small Heterodimer Partner Elevates Ileal Bile Acids and Alters Cell Cycle-related Genes in Male Mice.
Volume: 163
Issue: 6
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Publication
35133032 | J:330014
First Author: Bhat N
Year: 2022
Journal: FASEB J
Title: TCF7L2 transcriptionally regulates Fgf15 to maintain bile acid and lipid homeostasis through gut-liver crosstalk.
Volume: 36
Issue: 3
Pages: e22185
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Publication
38788959 | J:349748
 
First Author: Shi T
Year: 2024
Journal: Biochem Pharmacol
Title: Pregnane X receptor (PXR) deficiency promotes hepatocarcinogenesis via induction of Akr1c18 expression and prostaglandin F(2α) (PGF(2α)) levels.
Volume: 225
Pages: 116309
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28498614 | J:273941
First Author: Slijepcevic D
Year: 2017
Journal: Hepatology
Title: Hepatic uptake of conjugated bile acids is mediated by both sodium taurocholate cotransporting polypeptide and organic anion transporting polypeptides and modulated by intestinal sensing of plasma bile acid levels in mice.
Volume: 66
Issue: 5
Pages: 1631-1643
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28935756 | J:269250
First Author: Trenteseaux C
Year: 2017
Journal: Arterioscler Thromb Vasc Biol
Title: Perinatal Hypercholesterolemia Exacerbates Atherosclerosis Lesions in Offspring by Altering Metabolism of Trimethylamine-N-Oxide and Bile Acids.
Volume: 37
Issue: 11
Pages: 2053-2063
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16185916 | J:102525
First Author: Matasconi M
Year: 2005
Journal: Biochim Biophys Acta
Title: Pituitary control of cholesterol metabolism in normal and LDL receptor knock-out mice: effects of hypophysectomy and growth hormone treatment.
Volume: 1736
Issue: 3
Pages: 221-7
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Publication
24223822 | J:271016
First Author: Ellis EC
Year: 2013
Journal: PLoS One
Title: Mice with chimeric livers are an improved model for human lipoprotein metabolism.
Volume: 8
Issue: 11
Pages: e78550
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Publication
28973556 | J:273672
First Author: Zhang Y
Year: 2017
Journal: Toxicol Sci
Title: Editor's Highlight: Clofibrate Decreases Bile Acids in Livers of Male Mice by Increasing Biliary Bile Acid Excretion in a PPARα-Dependent Manner.
Volume: 160
Issue: 2
Pages: 351-360
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Publication
15750181 | J:99093
First Author: Yu C
Year: 2005
Journal: J Biol Chem
Title: Independent repression of bile acid synthesis and activation of c-Jun N-terminal kinase (JNK) by activated hepatocyte fibroblast growth factor receptor 4 (FGFR4) and bile acids.
Volume: 280
Issue: 18
Pages: 17707-14
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Publication
16357057 | J:111080
First Author: Zollner G
Year: 2006
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Coordinated induction of bile acid detoxification and alternative elimination in mice: role of FXR-regulated organic solute transporter-alpha/beta in the adaptive response to bile acids.
Volume: 290
Issue: 5
Pages: G923-32
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Publication
16606610 | J:113721
First Author: Yamamoto Y
Year: 2006
Journal: J Biol Chem
Title: Estrogen receptor alpha mediates 17alpha-ethynylestradiol causing hepatotoxicity.
Volume: 281
Issue: 24
Pages: 16625-31
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