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Search results 101 to 200 out of 498 for Flt3

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Type Details Score
Publication
21268003 | J:175430
First Author: Dolence JJ
Year: 2011
Journal: Eur J Immunol
Title: Threshold levels of Flt3-ligand are required for the generation and survival of lymphoid progenitors and B-cell precursors.
Volume: 41
Issue: 2
Pages: 324-34
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Publication
18458114 | J:136220
First Author: Benz C
Year: 2008
Journal: J Exp Med
Title: The stream of precursors that colonizes the thymus proceeds selectively through the early T lineage precursor stage of T cell development.
Volume: 205
Issue: 5
Pages: 1187-99
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Publication
30538245 | J:267590
First Author: Percin GI
Year: 2018
Journal: Nat Commun
Title: CSF1R regulates the dendritic cell pool size in adult mice via embryo-derived tissue-resident macrophages.
Volume: 9
Issue: 1
Pages: 5279
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Publication
18485879 | J:136338
First Author: Uren AG
Year: 2008
Journal: Cell
Title: Large-scale mutagenesis in p19(ARF)- and p53-deficient mice identifies cancer genes and their collaborative networks.
Volume: 133
Issue: 4
Pages: 727-41
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Publication
25456130 | J:218754
First Author: Chatterjee A
Year: 2014
Journal: Cell Rep
Title: Regulation of Stat5 by FAK and PAK1 in Oncogenic FLT3- and KIT-Driven Leukemogenesis.
Volume: 9
Issue: 4
Pages: 1333-48
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Publication
39532065 | J:359345
First Author: Bowman RL
Year: 2024
Journal: Cancer Cell
Title: In vivo models of subclonal oncogenesis and dependency in hematopoietic malignancy.
Volume: 42
Issue: 11
Pages: 1955-1969.e7
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Publication
19733489 | J:152688
First Author: Bogunovic M
Year: 2009
Journal: Immunity
Title: Origin of the lamina propria dendritic cell network.
Volume: 31
Issue: 3
Pages: 513-25
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Publication
35072209 | J:323098
 
First Author: Worthington AK
Year: 2022
Journal: Development
Title: IL7Rα, but not Flk2, is required for hematopoietic stem cell reconstitution of tissue-resident lymphoid cells.
Volume: 149
Issue: 8
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Publication
28835438 | J:246313
First Author: Dovey OM
Year: 2017
Journal: Blood
Title: Molecular synergy underlies the co-occurrence patterns and phenotype of NPM1-mutant acute myeloid leukemia.
Volume: 130
Issue: 17
Pages: 1911-1922
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Publication
34903841 | J:322606
First Author: Spohr C
Year: 2022
Journal: Leukemia
Title: Gab2 deficiency prevents Flt3-ITD driven acute myeloid leukemia in vivo.
Volume: 36
Issue: 4
Pages: 970-982
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Publication
22323452 | J:182518
First Author: Greenblatt S
Year: 2012
Journal: Blood
Title: Knock-in of a FLT3/ITD mutation cooperates with a NUP98-HOXD13 fusion to generate acute myeloid leukemia in a mouse model.
Volume: 119
Issue: 12
Pages: 2883-94
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Publication
29138056 | J:261189
First Author: Kim TG
Year: 2018
Journal: J Invest Dermatol
Title: Skin-Specific CD301b+ Dermal Dendritic Cells Drive IL-17-Mediated Psoriasis-Like Immune Response in Mice.
Volume: 138
Issue: 4
Pages: 844-853
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Publication
28637883 | J:244910
First Author: Mead AJ
Year: 2017
Journal: J Exp Med
Title: Niche-mediated depletion of the normal hematopoietic stem cell reservoir by Flt3-ITD-induced myeloproliferation.
Volume: 214
Issue: 7
Pages: 2005-2021
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Publication
28193779 | J:241017
First Author: Shih AH
Year: 2017
Journal: Cancer Discov
Title: Combination Targeted Therapy to Disrupt Aberrant Oncogenic Signaling and Reverse Epigenetic Dysfunction in IDH2- and TET2-Mutant Acute Myeloid Leukemia.
Volume: 7
Issue: 5
Pages: 494-505
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Publication
26453378 | J:233862
First Author: Nobs SP
Year: 2015
Journal: Immunity
Title: PI3-Kinase-γ Has a Distinct and Essential Role in Lung-Specific Dendritic Cell Development.
Volume: 43
Issue: 4
Pages: 674-89
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Publication
20008528 | J:155668
First Author: Ginhoux F
Year: 2009
Journal: J Exp Med
Title: The origin and development of nonlymphoid tissue CD103+ DCs.
Volume: 206
Issue: 13
Pages: 3115-30
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Publication
27879203 | J:239173
   
First Author: Porter SN
Year: 2016
Journal: Elife
Title: Fetal and neonatal hematopoietic progenitors are functionally and transcriptionally resistant to Flt3-ITD mutations.
Volume: 5
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Publication
8920882 | -
First Author: Maraskovsky E
Year: 1996
Journal: J Exp Med
Title: Dramatic increase in the numbers of functionally mature dendritic cells in Flt3 ligand-treated mice: multiple dendritic cell subpopulations identified.
Volume: 184
Issue: 5
Pages: 1953-62
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Publication
28825709 | J:269878
First Author: Agathocleous M
Year: 2017
Journal: Nature
Title: Ascorbate regulates haematopoietic stem cell function and leukaemogenesis.
Volume: 549
Issue: 7673
Pages: 476-481
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Publication
27046463 | J:233958
First Author: Müller TA
Year: 2016
Journal: Leukemia
Title: Lineage-specific STAT5 target gene activation in hematopoietic progenitor cells predicts the FLT3(+)-mediated leukemic phenotype.
Volume: 30
Issue: 8
Pages: 1725-33
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Publication
36395068 | J:336420
First Author: Li Y
Year: 2023
Journal: Blood
Title: FLT3ITD drives context-specific changes in cell identity and variable interferon dependence during AML initiation.
Volume: 141
Issue: 12
Pages: 1442-1456
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Publication
26627255 | J:228325
First Author: Svensson MN
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Murine germinal center B cells require functional Fms-like tyrosine kinase 3 signaling for IgG1 class-switch recombination.
Volume: 112
Issue: 48
Pages: E6644-53
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Publication
34750506 | J:336637
First Author: Charlet A
Year: 2022
Journal: Leukemia
Title: The IL-3, IL-5, and GM-CSF common receptor beta chain mediates oncogenic activity of FLT3-ITD-positive AML.
Volume: 36
Issue: 3
Pages: 701-711
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Publication
26865269 | J:250481
First Author: Li Y
Year: 2016
Journal: Eur J Immunol
Title: A novel Flt3-deficient HIS mouse model with selective enhancement of human DC development.
Volume: 46
Issue: 5
Pages: 1291-9
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Publication
25931014 | J:230783
First Author: Tang Y
Year: 2015
Journal: Exp Hematol
Title: Coexpression of hyperactivated AKT1 with additional genes activated in leukemia drives hematopoietic progenitor cells to cell cycle block and apoptosis.
Volume: 43
Issue: 7
Pages: 554-64
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Publication
27760321 | J:240820
First Author: Tzelepis K
Year: 2016
Journal: Cell Rep
Title: A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia.
Volume: 17
Issue: 4
Pages: 1193-1205
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Publication
7919361 | J:21273
First Author: Zeigler FC
Year: 1994
Journal: Blood
Title: Cellular and molecular characterization of the role of the flk-2/flt-3 receptor tyrosine kinase in hematopoietic stem cells.
Volume: 84
Issue: 8
Pages: 2422-30
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Publication
7507245 | J:16485
First Author: Small D
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: STK-1, the human homolog of Flk-2/Flt-3, is selectively expressed in CD34+ human bone marrow cells and is involved in the proliferation of early progenitor/stem cells.
Volume: 91
Issue: 2
Pages: 459-63
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Publication
8543798 | J:30540
First Author: Hunte BE
Year: 1996
Journal: J Immunol
Title: flk2/flt3 ligand is a potent cofactor for the growth of primitive B cell progenitors.
Volume: 156
Issue: 2
Pages: 489-96
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Publication
18424665 | J:136797
First Author: Karsunky H
Year: 2008
Journal: Blood
Title: Flk2+ common lymphoid progenitors possess equivalent differentiation potential for the B and T lineages.
Volume: 111
Issue: 12
Pages: 5562-70
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Publication
20472760 | J:163873
First Author: Mkonyi LE
Year: 2010
Journal: Am J Physiol Heart Circ Physiol
Title: Importance of lymph vessels in the transcapillary fluid balance in the gingiva studied in a transgenic mouse model.
Volume: 299
Issue: 2
Pages: H275-83
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Publication
22289922 | J:188973
First Author: Finnon R
Year: 2012
Journal: Leukemia
Title: Flt3-ITD mutations in a mouse model of radiation-induced acute myeloid leukaemia.
Volume: 26
Issue: 6
Pages: 1445-6
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Publication
33567267 | J:304636
     
First Author: Han X
Year: 2021
Journal: Cell Stem Cell
Title: A suite of new Dre recombinase drivers markedly expands the ability to perform intersectional genetic targeting.
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Publication
36580665 | J:337724
First Author: Vekariya U
Year: 2023
Journal: Blood
Title: DNA polymerase θ protects leukemia cells from metabolically induced DNA damage.
Volume: 141
Issue: 19
Pages: 2372-2389
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Publication
8145851 | J:36554
First Author: Hannum C
Year: 1994
Journal: Nature
Title: Ligand for FLT3/FLK2 receptor tyrosine kinase regulates growth of haematopoietic stem cells and is encoded by variant RNAs.
Volume: 368
Issue: 6472
Pages: 643-8
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7505204 | J:16458
First Author: Lyman SD
Year: 1993
Journal: Cell
Title: Molecular cloning of a ligand for the flt3/flk-2 tyrosine kinase receptor: a proliferative factor for primitive hematopoietic cells.
Volume: 75
Issue: 6
Pages: 1157-67
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Publication
22508930 | J:188667
First Author: Yin N
Year: 2012
Journal: J Immunol
Title: Functional specialization of islet dendritic cell subsets.
Volume: 188
Issue: 10
Pages: 4921-30
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Publication
32822583 | J:325521
First Author: Li Y
Year: 2020
Journal: Cell Stem Cell
Title: Single-Cell Analysis of Neonatal HSC Ontogeny Reveals Gradual and Uncoordinated Transcriptional Reprogramming that Begins before Birth.
Volume: 27
Issue: 5
Pages: 732-747.e7
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Publication
34446787 | J:313835
First Author: Droho S
Year: 2021
Journal: Sci Rep
Title: Dendritic cells play no significant role in the laser-induced choroidal neovascularization model.
Volume: 11
Issue: 1
Pages: 17254
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Publication
26392589 | J:242869
First Author: Svensson MN
Year: 2016
Journal: J Leukoc Biol
Title: Impaired signaling through the Fms-like tyrosine kinase 3 receptor increases osteoclast formation and bone damage in arthritis.
Volume: 99
Issue: 3
Pages: 413-23
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Publication
30064973 | J:265991
First Author: Pronier E
Year: 2018
Journal: Blood
Title: Genetic and epigenetic evolution as a contributor to WT1-mutant leukemogenesis.
Volume: 132
Issue: 12
Pages: 1265-1278
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Publication
23478666 | J:200121
First Author: Mupo A
Year: 2013
Journal: Leukemia
Title: A powerful molecular synergy between mutant Nucleophosmin and Flt3-ITD drives acute myeloid leukemia in mice.
Volume: 27
Issue: 9
Pages: 1917-20
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Publication
35122024 | J:334992
First Author: Scheller M
Year: 2021
Journal: Nat Cancer
Title: Hotspot DNMT3A mutations in clonal hematopoiesis and acute myeloid leukemia sensitize cells to azacytidine via viral mimicry response.
Volume: 2
Issue: 5
Pages: 527-544
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Publication
30205049 | J:265466
First Author: Brunetti L
Year: 2018
Journal: Cancer Cell
Title: Mutant NPM1 Maintains the Leukemic State through HOX Expression.
Volume: 34
Issue: 3
Pages: 499-512.e9
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Publication
26104662 | J:227310
First Author: Velasco-Hernandez T
Year: 2015
Journal: Leukemia
Title: Loss of HIF-1α accelerates murine FLT-3(ITD)-induced myeloproliferative neoplasia.
Volume: 29
Issue: 12
Pages: 2366-74
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Publication
35348887 | J:336084
First Author: Demircan MB
Year: 2022
Journal: J Cancer Res Clin Oncol
Title: Context-specific effects of NOX4 inactivation in acute myeloid leukemia (AML).
Volume: 148
Issue: 8
Pages: 1983-1990
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Publication
27207794 | J:236121
First Author: Zriwil A
Year: 2016
Journal: Blood
Title: Macrophage colony-stimulating factor receptor marks and regulates a fetal myeloid-primed B-cell progenitor in mice.
Volume: 128
Issue: 2
Pages: 217-26
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Publication
22025549 | J:179769
First Author: Yang Q
Year: 2011
Journal: J Immunol
Title: Cutting edge: Natural helper cells derive from lymphoid progenitors.
Volume: 187
Issue: 11
Pages: 5505-9
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Publication
34880496 | J:336509
First Author: Fennell KA
Year: 2022
Journal: Nature
Title: Non-genetic determinants of malignant clonal fitness at single-cell resolution.
Volume: 601
Issue: 7891
Pages: 125-131
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Publication
31286998 | J:294445
First Author: Solovey M
Year: 2019
Journal: J Hematol Oncol
Title: Nuclear factor of activated T-cells, NFATC1, governs FLT3ITD-driven hematopoietic stem cell transformation and a poor prognosis in AML.
Volume: 12
Issue: 1
Pages: 72
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Publication
25534201 | J:230276
First Author: Taylor SJ
Year: 2015
Journal: Exp Hematol
Title: Loss of c-Cbl E3 ubiquitin ligase activity enhances the development of myeloid leukemia in FLT3-ITD mutant mice.
Volume: 43
Issue: 3
Pages: 191-206.e1
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Publication
27775550 | J:239702
First Author: Mundy-Bosse BL
Year: 2016
Journal: J Clin Invest
Title: MicroRNA-29b mediates altered innate immune development in acute leukemia.
Volume: 126
Issue: 12
Pages: 4404-4416
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Publication
31337857 | J:284058
First Author: Wang H
Year: 2020
Journal: Leukemia
Title: Targeting cell membrane HDM2: A novel therapeutic approach for acute myeloid leukemia.
Volume: 34
Issue: 1
Pages: 75-86
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Publication
33589748 | J:308178
First Author: Nguyen LXT
Year: 2021
Journal: Leukemia
Title: Cytoplasmic DROSHA and non-canonical mechanisms of MiR-155 biogenesis in FLT3-ITD acute myeloid leukemia.
Volume: 35
Issue: 8
Pages: 2285-2298
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32094205 | J:287542
First Author: Buteyn NJ
Year: 2020
Journal: J Immunol
Title: Activation of the Intracellular Pattern Recognition Receptor NOD2 Promotes Acute Myeloid Leukemia (AML) Cell Apoptosis and Provides a Survival Advantage in an Animal Model of AML.
Volume: 204
Issue: 7
Pages: 1988-1997
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35412895 | J:329928
First Author: Hoang DH
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: MicroRNA networks in FLT3-ITD acute myeloid leukemia.
Volume: 119
Issue: 16
Pages: e2112482119
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Publication
23660685 | J:203559
First Author: Bernot KM
Year: 2013
Journal: Leukemia
Title: Toward personalized therapy in AML: in vivo benefit of targeting aberrant epigenetics in MLL-PTD-associated AML.
Volume: 27
Issue: 12
Pages: 2379-82
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24994068 | J:214640
First Author: Wang Y
Year: 2014
Journal: Blood
Title: Echinomycin protects mice against relapsed acute myeloid leukemia without adverse effect on hematopoietic stem cells.
Volume: 124
Issue: 7
Pages: 1127-35
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33902106 | J:334851
First Author: Yankova E
Year: 2021
Journal: Nature
Title: Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia.
Volume: 593
Issue: 7860
Pages: 597-601
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23584564 | J:202794
First Author: Mallardo M
Year: 2013
Journal: Leukemia
Title: NPMc+ and FLT3_ITD mutations cooperate in inducing acute leukaemia in a novel mouse model.
Volume: 27
Issue: 11
Pages: 2248-51
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37580596 | J:354061
First Author: Lara-Astiaso D
Year: 2023
Journal: Nat Genet
Title: In vivo screening characterizes chromatin factor functions during normal and malignant hematopoiesis.
Volume: 55
Issue: 9
Pages: 1542-1554
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9216738 | J:41397
First Author: Pharr PN
Year: 1997
Journal: Exp Hematol
Title: Loss of flk-2/flt3 expression during commitment of multipotent mouse hematopoietic progenitor cells to the mast cell lineage.
Volume: 25
Issue: 7
Pages: 620-8
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32895539 | J:306423
First Author: Williams JW
Year: 2020
Journal: Nat Immunol
Title: Limited proliferation capacity of aortic intima resident macrophages requires monocyte recruitment for atherosclerotic plaque progression.
Volume: 21
Issue: 10
Pages: 1194-1204
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Publication
36681742 | J:333989
First Author: Romine KA
Year: 2023
Journal: Leukemia
Title: BET inhibitors rescue anti-PD1 resistance by enhancing TCF7 accessibility in leukemia-derived terminally exhausted CD8(+) T cells.
Volume: 37
Issue: 3
Pages: 580-592
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31648326 | J:360102
First Author: Moshofsky KB
Year: 2019
Journal: Blood Adv
Title: Acute myeloid leukemia-induced T-cell suppression can be reversed by inhibition of the MAPK pathway.
Volume: 3
Issue: 20
Pages: 3038-3051
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32541670 | J:291905
First Author: Vu T
Year: 2020
Journal: Nat Commun
Title: Hematopoietic stem and progenitor cell-restricted Cdx2 expression induces transformation to myelodysplasia and acute leukemia.
Volume: 11
Issue: 1
Pages: 3021
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28077417 | J:240697
First Author: Kunimoto H
Year: 2017
Journal: Blood
Title: Aid is a key regulator of myeloid/erythroid differentiation and DNA methylation in hematopoietic stem/progenitor cells.
Volume: 129
Issue: 13
Pages: 1779-1790
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9326216 | J:43143
First Author: Liu F
Year: 1997
Journal: Blood
Title: The granulocyte colony-stimulating factor receptor is required for the mobilization of murine hematopoietic progenitors into peripheral blood by cyclophosphamide or interleukin-8 but not flt-3 ligand.
Volume: 90
Issue: 7
Pages: 2522-8
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19273628 | J:146747
First Author: Auffray C
Year: 2009
Journal: J Exp Med
Title: CX3CR1+ CD115+ CD135+ common macrophage/DC precursors and the role of CX3CR1 in their response to inflammation.
Volume: 206
Issue: 3
Pages: 595-606
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24440599 | J:210097
First Author: Kats LM
Year: 2014
Journal: Cell Stem Cell
Title: Proto-oncogenic role of mutant IDH2 in leukemia initiation and maintenance.
Volume: 14
Issue: 3
Pages: 329-41
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30675010 | J:276578
First Author: Nabinger SC
Year: 2019
Journal: Leukemia
Title: Mutant p53 enhances leukemia-initiating cell self-renewal to promote leukemia development.
Volume: 33
Issue: 6
Pages: 1535-1539
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Publication
29186125 | J:271419
First Author: Barbieri I
Year: 2017
Journal: Nature
Title: Promoter-bound METTL3 maintains myeloid leukaemia by m6A-dependent translation control.
Volume: 552
Issue: 7683
Pages: 126-131
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32579941 | J:300229
First Author: Cai Z
Year: 2020
Journal: Cell Rep
Title: Targeting Bim via a lncRNA Morrbid Regulates the Survival of Preleukemic and Leukemic Cells.
Volume: 31
Issue: 12
Pages: 107816
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23528808 | J:215298
First Author: Kazi JU
Year: 2013
Journal: Exp Hematol
Title: The presence or absence of IL-3 during long-term culture of Flt3-ITD and c-Kit-D816V expressing Ba/F3 cells influences signaling outcome.
Volume: 41
Issue: 7
Pages: 585-7
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34732858 | J:321265
First Author: Yang M
Year: 2022
Journal: Leukemia
Title: A unique role of p53 haploinsufficiency or loss in the development of acute myeloid leukemia with FLT3-ITD mutation.
Volume: 36
Issue: 3
Pages: 675-686
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34352207 | J:355249
First Author: Orellana EA
Year: 2021
Journal: Mol Cell
Title: METTL1-mediated m(7)G modification of Arg-TCT tRNA drives oncogenic transformation.
Volume: 81
Issue: 16
Pages: 3323-3338.e14
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34417259 | J:350625
First Author: Lordo MR
Year: 2021
Journal: J Immunol
Title: Acute Myeloid Leukemia Alters Group 1 Innate Lymphoid Cell Differentiation from a Common Precursor.
Volume: 207
Issue: 6
Pages: 1672-1682
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17277104 | J:144001
First Author: Schwarz BA
Year: 2007
Journal: J Immunol
Title: Selective thymus settling regulated by cytokine and chemokine receptors.
Volume: 178
Issue: 4
Pages: 2008-17
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31378988 | J:278786
     
First Author: Labarthe L
Year: 2019
Journal: J Leukoc Biol
Title: Frontline Science: Exhaustion and senescence marker profiles on human T cells in BRGSF-A2 humanized mice resemble those in human samples.
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38495876 | J:346379
 
First Author: Flynn PA
Year: 2024
Journal: Front Immunol
Title: Leukemic mutation FLT3-ITD is retained in dendritic cells and disrupts their homeostasis leading to expanded Th17 frequency.
Volume: 15
Pages: 1297338
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16688530 | J:105543
First Author: Crozat K
Year: 2006
Journal: Mamm Genome
Title: Analysis of the MCMV resistome by ENU mutagenesis.
Volume: 17
Issue: 5
Pages: 398-406
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28823558 | J:252191
First Author: Cimmino L
Year: 2017
Journal: Cell
Title: Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression.
Volume: 170
Issue: 6
Pages: 1079-1095.e20
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19733097 | J:152689
First Author: Varol C
Year: 2009
Journal: Immunity
Title: Intestinal lamina propria dendritic cell subsets have different origin and functions.
Volume: 31
Issue: 3
Pages: 502-12
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Publication
24591364 | J:209877
First Author: Jiao J
Year: 2014
Journal: J Immunol
Title: Central role of conventional dendritic cells in regulation of bone marrow release and survival of neutrophils.
Volume: 192
Issue: 7
Pages: 3374-82
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