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Search results 101 to 200 out of 254 for Grn

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Category: Publication
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Type Details Score
Publication
26206194 | J:228147
First Author: Minami SS
Year: 2015
Journal: Biochem Pharmacol
Title: Reducing inflammation and rescuing FTD-related behavioral deficits in progranulin-deficient mice with α7 nicotinic acetylcholine receptor agonists.
Volume: 97
Issue: 4
Pages: 454-462
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Publication
32792571 | J:299286
First Author: Telpoukhovskaia MA
Year: 2020
Journal: Sci Rep
Title: Discovery of small molecules that normalize the transcriptome and enhance cysteine cathepsin activity in progranulin-deficient microglia.
Volume: 10
Issue: 1
Pages: 13688
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Publication
30696728 | J:277911
First Author: Elia LP
Year: 2019
Journal: J Neurosci
Title: Genetic Regulation of Neuronal Progranulin Reveals a Critical Role for the Autophagy-Lysosome Pathway.
Volume: 39
Issue: 17
Pages: 3332-3344
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Publication
10625564 | J:59921
First Author: Díaz-Cueto L
Year: 2000
Journal: Dev Biol
Title: Modulation of mouse preimplantation embryo development by acrogranin (epithelin/granulin precursor).
Volume: 217
Issue: 2
Pages: 406-18
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Publication
25626394 | J:247264
First Author: Huang K
Year: 2015
Journal: Immunology
Title: Progranulin is preferentially expressed in patients with psoriasis vulgaris and protects mice from psoriasis-like skin inflammation.
Volume: 145
Issue: 2
Pages: 279-87
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Publication
29625085 | J:268496
First Author: Li L
Year: 2018
Journal: Exp Cell Res
Title: Progranulin ameliorates coxsackievirus-B3-induced viral myocarditis by downregulating Th1 and Th17 cells.
Volume: 367
Issue: 2
Pages: 241-250
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Publication
32247641 | J:289979
 
First Author: Huang G
Year: 2020
Journal: J Mol Cell Cardiol
Title: Potential role of full-length and nonfull-length progranulin in affecting aortic valve calcification.
Volume: 141
Pages: 93-104
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Publication
31679689 | J:291783
First Author: Li X
Year: 2020
Journal: Biochem Biophys Res Commun
Title: Progranulin protects against cerebral ischemia-reperfusion (I/R) injury by inhibiting necroptosis and oxidative stress.
Volume: 521
Issue: 3
Pages: 569-576
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Publication
31285425 | J:295490
First Author: Zhou D
Year: 2019
Journal: Cell Death Dis
Title: PGRN acts as a novel regulator of mitochondrial homeostasis by facilitating mitophagy and mitochondrial biogenesis to prevent podocyte injury in diabetic nephropathy.
Volume: 10
Issue: 7
Pages: 524
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Publication
31990656 | J:305629
First Author: Li H
Year: 2020
Journal: J Mol Endocrinol
Title: PGRN exerts inflammatory effects via SIRT1-NF-κB in adipose insulin resistance.
Volume: 64
Issue: 3
Pages: 181-193
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Publication
21152114 | J:309154
First Author: Cao Z
Year: 2010
Journal: Int J Biol Sci
Title: GEP, a local growth factor, is critical for odontogenesis and amelogenesis.
Volume: 6
Issue: 7
Pages: 719-29
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Publication
27367257 | J:315439
 
First Author: Xu X
Year: 2016
Journal: Int Immunopharmacol
Title: Progranulin protects against endotoxin-induced acute kidney injury by downregulating renal cell death and inflammatory responses in mice.
Volume: 38
Pages: 409-19
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Publication
27215202 | J:330997
First Author: Ma Y
Year: 2017
Journal: Mol Neurobiol
Title: Progranulin Protects Hippocampal Neurogenesis via Suppression of Neuroinflammatory Responses Under Acute Immune Stress.
Volume: 54
Issue: 5
Pages: 3717-3728
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Publication
12526812 | J:269644
First Author: Zhu J
Year: 2002
Journal: Cell
Title: Conversion of proepithelin to epithelins: roles of SLPI and elastase in host defense and wound repair.
Volume: 111
Issue: 6
Pages: 867-78
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Publication
23041626 | J:188324
First Author: Martens LH
Year: 2012
Journal: J Clin Invest
Title: Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury.
Volume: 122
Issue: 11
Pages: 3955-9
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Publication
21368173 | J:170823
First Author: Kao AW
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: A neurodegenerative disease mutation that accelerates the clearance of apoptotic cells.
Volume: 108
Issue: 11
Pages: 4441-6
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Publication
31391467 | J:279303
First Author: Ramadori G
Year: 2019
Journal: Nat Commun
Title: S100A9 extends lifespan in insulin deficiency.
Volume: 10
Issue: 1
Pages: 3545
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Publication
35933009 | J:329288
First Author: Santos MN
Year: 2022
Journal: J Biol Chem
Title: Progranulin-derived granulin E and lysosome membrane protein CD68 interact to reciprocally regulate their protein homeostasis.
Volume: 298
Issue: 9
Pages: 102348
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Publication
32852886 | J:301380
First Author: Feng T
Year: 2020
Journal: EMBO Rep
Title: Loss of TMEM106B and PGRN leads to severe lysosomal abnormalities and neurodegeneration in mice.
Volume: 21
Issue: 10
Pages: e50219
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Publication
37519899 | J:350844
First Author: Feng T
Year: 2023
Journal: iScience
Title: AAV-GRN partially corrects motor deficits and ALS/FTLD-related pathology in Tmem106b(-/-)Grn(-/-) mice.
Volume: 26
Issue: 7
Pages: 107247
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Publication
29396296 | J:274924
 
First Author: Jian J
Year: 2018
Journal: EBioMedicine
Title: Chitinase-3-like Protein 1: A Progranulin Downstream Molecule and Potential Biomarker for Gaucher Disease.
Volume: 28
Pages: 251-260
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Publication
31237618 | J:279769
First Author: Wang L
Year: 2019
Journal: Endocrinology
Title: Female-Specific Role of Progranulin to Suppress Bone Formation.
Volume: 160
Issue: 9
Pages: 2024-2037
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Publication
27114033 | J:234491
First Author: Lui H
Year: 2016
Journal: Cell
Title: Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation.
Volume: 165
Issue: 4
Pages: 921-35
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32761777 | J:299153
First Author: Zhou X
Year: 2020
Journal: EMBO Rep
Title: Loss of Tmem106b exacerbates FTLD pathologies and causes motor deficits in progranulin-deficient mice.
Volume: 21
Issue: 10
Pages: e50197
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Publication
38499658 | J:351848
First Author: Ounissi M
Year: 2024
Journal: Sci Rep
Title: PhagoStat a scalable and interpretable end to end framework for efficient quantification of cell phagocytosis in neurodegenerative disease studies.
Volume: 14
Issue: 1
Pages: 6482
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Publication
29398357 | J:261277
First Author: Uesaka N
Year: 2018
Journal: Neuron
Title: Retrograde Signaling from Progranulin to Sort1 Counteracts Synapse Elimination in the Developing Cerebellum.
Volume: 97
Issue: 4
Pages: 796-805.e5
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Publication
17307734 | J:121129
First Author: Xu K
Year: 2007
Journal: J Biol Chem
Title: Cartilage oligomeric matrix protein associates with granulin-epithelin precursor (GEP) and potentiates GEP-stimulated chondrocyte proliferation.
Volume: 282
Issue: 15
Pages: 11347-55
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Publication
12889069 | J:84942
First Author: Daniel R
Year: 2003
Journal: Dev Dyn
Title: Progranulin (acrogranin/PC cell-derived growth factor/granulin-epithelin precursor) is expressed in the placenta, epidermis, microvasculature, and brain during murine development.
Volume: 227
Issue: 4
Pages: 593-9
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Publication
24383743 | J:211954
First Author: Hu Y
Year: 2014
Journal: Immunology
Title: Progranulin promotes tumour necrosis factor-induced proliferation of suppressive mouse CD4⁺ Foxp3⁺ regulatory T cells.
Volume: 142
Issue: 2
Pages: 193-201
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Publication
23847387 | J:219323
First Author: Kawase R
Year: 2013
Journal: Cardiovasc Res
Title: Deletion of progranulin exacerbates atherosclerosis in ApoE knockout mice.
Volume: 100
Issue: 1
Pages: 125-33
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Publication
29096020 | J:271787
First Author: Zhang K
Year: 2017
Journal: Brain
Title: Elevated progranulin contributes to synaptic and learning deficit due to loss of fragile X mental retardation protein.
Volume: 140
Issue: 12
Pages: 3215-3232
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Publication
31086348 | J:289192
First Author: Yousef H
Year: 2019
Journal: Nat Med
Title: Aged blood impairs hippocampal neural precursor activity and activates microglia via brain endothelial cell VCAM1.
Volume: 25
Issue: 6
Pages: 988-1000
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Publication
28640985 | J:245104
First Author: Zhou X
Year: 2017
Journal: J Neurochem
Title: The interaction between progranulin and prosaposin is mediated by granulins and the linker region between saposin B and C.
Volume: 143
Issue: 2
Pages: 236-243
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Publication
19487464 | J:151330
First Author: Bai XH
Year: 2009
Journal: Mol Cell Biol
Title: ADAMTS-7, a direct target of PTHrP, adversely regulates endochondral bone growth by associating with and inactivating GEP growth factor.
Volume: 29
Issue: 15
Pages: 4201-19
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Publication
33796852 | J:311484
First Author: Perez-Canamas A
Year: 2021
Journal: Brain Commun
Title: Fronto-temporal dementia risk gene TMEM106B has opposing effects in different lysosomal storage disorders.
Volume: 3
Issue: 1
Pages: fcaa200
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Publication
30619312 | J:281822
 
First Author: Wang Z
Year: 2018
Journal: Front Immunol
Title: Innate Anti-microbial and Anti-chemotaxis Properties of Progranulin in an Acute Otitis Media Mouse Model.
Volume: 9
Pages: 2952
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Publication
36574647 | J:357412
First Author: Zhao X
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: PGRN deficiency exacerbates, whereas a brain penetrant PGRN derivative protects, GBA1 mutation-associated pathologies and diseases.
Volume: 120
Issue: 1
Pages: e2210442120
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39101473 | J:356433
     
First Author: Lin Y
Year: 2024
Journal: Hum Mol Genet
Title: Intrinsic link between PGRN and Gba1 D409V mutation dosage in potentiating Gaucher disease.
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Publication
25607110 | J:311071
First Author: Zhou M
Year: 2015
Journal: Kidney Int
Title: Progranulin protects against renal ischemia/reperfusion injury in mice.
Volume: 87
Issue: 5
Pages: 918-29
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Publication
25393765 | J:225148
First Author: Wei F
Year: 2014
Journal: PLoS One
Title: Progranulin facilitates conversion and function of regulatory T cells under inflammatory conditions.
Volume: 9
Issue: 11
Pages: e112110
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Publication
27030285 | J:259305
 
First Author: Kuse Y
Year: 2016
Journal: Sci Rep
Title: Progranulin promotes the retinal precursor cell proliferation and the photoreceptor differentiation in the mouse retina.
Volume: 6
Pages: 23811
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Publication
38678021 | J:347715
First Author: Raymant M
Year: 2024
Journal: Nat Commun
Title: Macrophage-fibroblast JAK/STAT dependent crosstalk promotes liver metastatic outgrowth in pancreatic cancer.
Volume: 15
Issue: 1
Pages: 3593
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8703129 | J:35465
First Author: Bucan M
Year: 1996
Journal: Mamm Genome
Title: Mapping of Grn, the gene encoding the granulin/epithelin precursor (acrogranin), to mouse chromosome 11.
Volume: 7
Issue: 9
Pages: 704-5
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Publication
19046946 | J:147807
 
First Author: Moisse K
Year: 2009
Journal: Brain Res
Title: Divergent patterns of cytosolic TDP-43 and neuronal progranulin expression following axotomy: implications for TDP-43 in the physiological response to neuronal injury.
Volume: 1249
Pages: 202-11
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Publication
22967900 | J:190133
First Author: Hu SY
Year: 2012
Journal: FEBS Lett
Title: Progranulin compensates for blocked IGF-1 signaling to promote myotube hypertrophy in C2C12 myoblasts via the PI3K/Akt/mTOR pathway.
Volume: 586
Issue: 19
Pages: 3485-92
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Publication
23746860 | J:315299
First Author: Zhao YP
Year: 2013
Journal: Biomaterials
Title: The promotion of bone healing by progranulin, a downstream molecule of BMP-2, through interacting with TNF/TNFR signaling.
Volume: 34
Issue: 27
Pages: 6412-21
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Publication
26039714 | J:319163
First Author: Li H
Year: 2015
Journal: Cell Cycle
Title: Administration of progranulin (PGRN) triggers ER stress and impairs insulin sensitivity via PERK-eIF2α-dependent manner.
Volume: 14
Issue: 12
Pages: 1893-907
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Publication
27789271 | J:269546
 
First Author: Jian J
Year: 2016
Journal: EBioMedicine
Title: Progranulin Recruits HSP70 to β-Glucocerebrosidase and Is Therapeutic Against Gaucher Disease.
Volume: 13
Pages: 212-224
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Publication
31484831 | J:296734
 
First Author: Huang A
Year: 2019
Journal: JCI Insight
Title: Progranulin prevents regulatory NK cell cytotoxicity against antiviral T cells.
Volume: 4
Issue: 17
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Publication
21393509 | J:171041
First Author: Tang W
Year: 2011
Journal: Science
Title: The growth factor progranulin binds to TNF receptors and is therapeutic against inflammatory arthritis in mice.
Volume: 332
Issue: 6028
Pages: 478-84
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Publication
32866962 | J:300323
First Author: Zhang J
Year: 2020
Journal: Nature
Title: Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency.
Volume: 588
Issue: 7838
Pages: 459-465
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Publication
27619993 | J:329609
First Author: Yan W
Year: 2016
Journal: J Immunol
Title: Progranulin Controls Sepsis via C/EBPα-Regulated Il10 Transcription and Ubiquitin Ligase/Proteasome-Mediated Protein Degradation.
Volume: 197
Issue: 8
Pages: 3393-3405
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Publication
38355776 | J:361131
First Author: Astuti Y
Year: 2024
Journal: Nat Cancer
Title: Efferocytosis reprograms the tumor microenvironment to promote pancreatic cancer liver metastasis.
Volume: 5
Issue: 5
Pages: 774-790
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Publication
29382817 | J:259943
First Author: Fujita K
Year: 2018
Journal: Nat Commun
Title: Targeting Tyro3 ameliorates a model of PGRN-mutant FTLD-TDP via tau-mediated synaptic pathology.
Volume: 9
Issue: 1
Pages: 433
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Publication
31866375 | J:301899
 
First Author: Zhu Y
Year: 2020
Journal: J Mol Cell Cardiol
Title: Progranulin deficiency leads to enhanced age-related cardiac hypertrophy through complement C1q-induced β-catenin activation.
Volume: 138
Pages: 197-211
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Publication
24652679 | J:210972
First Author: Caesar M
Year: 2014
Journal: Glia
Title: Changes in matrix metalloprotease activity and progranulin levels may contribute to the pathophysiological function of mutant leucine-rich repeat kinase 2.
Volume: 62
Issue: 7
Pages: 1075-92
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Publication
26892362 | J:274925
 
First Author: Mundra JJ
Year: 2016
Journal: Sci Rep
Title: Progranulin inhibits expression and release of chemokines CXCL9 and CXCL10 in a TNFR1 dependent manner.
Volume: 6
Pages: 21115
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Publication
32945448 | J:305738
First Author: Xu B
Year: 2020
Journal: Mol Med Rep
Title: Abnormal angiogenesis of placenta in progranulin‑deficient mice.
Volume: 22
Issue: 4
Pages: 3482-3492
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Publication
24070898 | J:202010
First Author: Jian J
Year: 2013
Journal: FEBS Lett
Title: Progranulin directly binds to the CRD2 and CRD3 of TNFR extracellular domains.
Volume: 587
Issue: 21
Pages: 3428-36
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Publication
27075243 | J:239480
First Author: Kong L
Year: 2016
Journal: FASEB J
Title: Extracellular matrix protein 1, a direct targeting molecule of parathyroid hormone-related peptide, negatively regulates chondrogenesis and endochondral ossification via associating with progranulin growth factor.
Volume: 30
Issue: 8
Pages: 2741-54
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28899992 | J:319244
First Author: Longhena F
Year: 2017
Journal: J Pharmacol Exp Ther
Title: Depletion of Progranulin Reduces GluN2B-Containing NMDA Receptor Density, Tau Phosphorylation, and Dendritic Arborization in Mouse Primary Cortical Neurons.
Volume: 363
Issue: 2
Pages: 164-175
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Publication
26370502 | J:227553
First Author: Zhou X
Year: 2015
Journal: J Cell Biol
Title: Prosaposin facilitates sortilin-independent lysosomal trafficking of progranulin.
Volume: 210
Issue: 6
Pages: 991-1002
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28835281 | J:269551
First Author: Zhou X
Year: 2017
Journal: Mol Neurodegener
Title: Lysosomal processing of progranulin.
Volume: 12
Issue: 1
Pages: 62
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Publication
25387791 | J:279616
 
First Author: Wei F
Year: 2014
Journal: Sci Rep
Title: PGRN protects against colitis progression in mice in an IL-10 and TNFR2 dependent manner.
Volume: 4
Pages: 7023
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Publication
28011648 | J:274503
First Author: Fu W
Year: 2017
Journal: FASEB J
Title: Foxo4- and Stat3-dependent IL-10 production by progranulin in regulatory T cells restrains inflammatory arthritis.
Volume: 31
Issue: 4
Pages: 1354-1367
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Publication
36121866 | J:330853
First Author: Liu J
Year: 2022
Journal: PLoS Pathog
Title: Progranulin aggravates lethal Candida albicans sepsis by regulating inflammatory response and antifungal immunity.
Volume: 18
Issue: 9
Pages: e1010873
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9434940 | J:42692
First Author: Sato H
Year: 1998
Journal: Mamm Genome
Title: A new mutation Rim3 resembling Re(den) is mapped close to retinoic acid receptor alpha (Rara) gene on mouse chromosome 11.
Volume: 9
Issue: 1
Pages: 20-5
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Publication
38573860 | J:347619
First Author: Zhang L
Year: 2024
Journal: Cell Rep
Title: Regulation of muscle hypertrophy through granulin: Relayed communication among mesenchymal progenitors, macrophages, and satellite cells.
Volume: 43
Issue: 4
Pages: 114052
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Publication
34130995 | J:308471
 
First Author: Homma H
Year: 2021
Journal: Life Sci Alliance
Title: DNA damage in embryonic neural stem cell determines FTLDs' fate via early-stage neuronal necrosis.
Volume: 4
Issue: 7
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Publication
34480901 | J:310638
First Author: Nies SH
Year: 2021
Journal: J Biol Chem
Title: Spreading of Alzheimer tau seeds is enhanced by aging and template matching with limited impact of amyloid-β.
Volume: 297
Issue: 4
Pages: 101159
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Publication
34385591 | J:348199
First Author: Jin M
Year: 2021
Journal: Commun Biol
Title: Prediction and verification of the AD-FTLD common pathomechanism based on dynamic molecular network analysis.
Volume: 4
Issue: 1
Pages: 961
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9096121 | J:39309
First Author: Rajan L
Year: 1997
Journal: Mamm Genome
Title: An MMTV integration site maps near the distal end of mouse chromosome 11.
Volume: 8
Issue: 4
Pages: 295-6
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23774650 | J:310933
 
First Author: Rutherford NJ
Year: 2013
Journal: Brain Res
Title: Unbiased screen reveals ubiquilin-1 and -2 highly associated with huntingtin inclusions.
Volume: 1524
Pages: 62-73
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10087197 | J:54007
First Author: Sato H
Year: 1999
Journal: Genomics
Title: The genomic organization of type I keratin genes in mice.
Volume: 56
Issue: 3
Pages: 303-9
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9218537 | J:42267
First Author: Kandil E
Year: 1997
Journal: Immunogenetics
Title: PA28 subunits of the mouse proteasome: primary structures and chromosomal localization of the genes.
Volume: 46
Issue: 4
Pages: 337-44
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37897724 | J:342618
First Author: Thomasen PB
Year: 2023
Journal: Cell Rep
Title: SorCS2 binds progranulin to regulate motor neuron development.
Volume: 42
Issue: 11
Pages: 113333
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9382924 | J:44713
First Author: Kohda K
Year: 1997
Journal: Immunogenetics
Title: Structural analysis and chromosomal localization of the mouse Psmb5 gene coding for the constitutively expressed beta-type proteasome subunit.
Volume: 47
Issue: 1
Pages: 77-87
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Publication
31550482 | J:278988
     
First Author: Tian C
Year: 2019
Journal: Dev Biol
Title: TBX1 is required for normal stria vascularis and semicircular canal development.
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Publication
12205107 | J:78525
First Author: Lemon WJ
Year: 2002
Journal: J Med Genet
Title: Identification of candidate lung cancer susceptibility genes in mouse using oligonucleotide arrays.
Volume: 39
Issue: 9
Pages: 644-55
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Publication
11044607 | J:65653
First Author: Wertz K
Year: 2000
Journal: Mech Dev
Title: Large-scale screen for genes involved in gonad development.
Volume: 98
Issue: 1-2
Pages: 51-70
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Publication
- | J:169366
     
First Author: MouseBookTM
Year: 2005
Journal: Unpublished
Title: Information obtained from MouseBookTM, Medical Research Council Mammalian Genetics Unit, Harwell, UK.
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24006456 | J:221550
First Author: Abonnenc M
Year: 2013
Journal: Circ Res
Title: Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.
Volume: 113
Issue: 10
Pages: 1138-47
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9371744 | J:44483
First Author: Brady KP
Year: 1997
Journal: Genome Res
Title: Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis.
Volume: 7
Issue: 11
Pages: 1085-93
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
32290105 | J:282558
 
First Author: Collin GB
Year: 2020
Journal: Cells
Title: Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss.
Volume: 9
Issue: 4
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Publication
- | J:101977
     
First Author: The Jackson Laboratory
Year: 2005
Journal: Unpublished
Title: Information obtained from The Jackson Laboratory, Bar Harbor, ME
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Publication
14651853 | J:86816
First Author: Mootha VK
Year: 2003
Journal: Cell
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Year: 2024
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Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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