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Search results 101 to 200 out of 803 for Hprt1

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Category: Publication
Type Details Score
Publication
First Author: Haywood NJ
Year: 2021
Journal: EMBO Rep
Title: Endothelial IGF-1 receptor mediates crosstalk with the gut wall to regulate microbiota in obesity.
Volume: 22
Issue: 5
Pages: e50767
Publication
First Author: Plucińska K
Year: 2014
Journal: J Neurosci
Title: Knock-in of human BACE1 cleaves murine APP and reiterates Alzheimer-like phenotypes.
Volume: 34
Issue: 32
Pages: 10710-28
Publication
First Author: Plucińska K
Year: 2016
Journal: Diabetologia
Title: Neuronal human BACE1 knockin induces systemic diabetes in mice.
Volume: 59
Issue: 7
Pages: 1513-1523
Publication
First Author: Dekeryte R
Year: 2021
Journal: Biochim Biophys Acta Mol Basis Dis
Title: The BACE1 inhibitor LY2886721 improves diabetic phenotypes of BACE1 knock-in mice.
Volume: 1867
Issue: 7
Pages: 166149
Publication  
First Author: Pan X
Year: 2019
Journal: Neuroscience
Title: Temporal Effects of Neuron-specific beta-secretase 1 (BACE1) Knock-in on the Mouse Brain Metabolome: Implications for Alzheimer's Disease.
Volume: 397
Pages: 138-146
Publication  
First Author: López-Soldado I
Year: 2023
Journal: Int J Mol Sci
Title: Active Glycogen Synthase in the Liver Prevents High-Fat Diet-Induced Glucose Intolerance, Decreases Food Intake, and Lowers Body Weight.
Volume: 24
Issue: 3
Publication
First Author: López-Soldado I
Year: 2015
Journal: Diabetes
Title: Liver glycogen reduces food intake and attenuates obesity in a high-fat diet-fed mouse model.
Volume: 64
Issue: 3
Pages: 796-807
Publication
First Author: Chang AS
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Prolactin alters blood pressure by modulating the activity of endothelial nitric oxide synthase.
Volume: 113
Issue: 44
Pages: 12538-12543
Publication
First Author: Birch J
Year: 2016
Journal: Biol Open
Title: The initiator methionine tRNA drives cell migration and invasion leading to increased metastatic potential in melanoma.
Volume: 5
Issue: 10
Pages: 1371-1379
Publication
First Author: Clarke CJ
Year: 2016
Journal: Curr Biol
Title: The Initiator Methionine tRNA Drives Secretion of Type II Collagen from Stromal Fibroblasts to Promote Tumor Growth and Angiogenesis.
Volume: 26
Issue: 6
Pages: 755-65
Publication
First Author: Bondulich MK
Year: 2016
Journal: Brain
Title: Tauopathy induced by low level expression of a human brain-derived tau fragment in mice is rescued by phenylbutyrate.
Volume: 139
Issue: Pt 8
Pages: 2290-306
Publication  
First Author: Tamagnini F
Year: 2017
Journal: Neurobiol Aging
Title: Hippocampal neurophysiology is modified by a disease-associated C-terminal fragment of tau protein.
Volume: 60
Pages: 44-56
Publication
First Author: Aizawa S
Year: 2022
Journal: Stem Cell Reports
Title: Early reactivation of clustered genes on the inactive X chromosome during somatic cell reprogramming.
Volume: 17
Issue: 1
Pages: 53-67
Publication
First Author: Simon CS
Year: 2020
Journal: Dev Cell
Title: Live Visualization of ERK Activity in the Mouse Blastocyst Reveals Lineage-Specific Signaling Dynamics.
Volume: 55
Issue: 3
Pages: 341-353.e5
Publication        
First Author: Lanza D
Year: 2023
Title: An Oocyte-specific Cas9-expressing mouse for germline CRISPR/Cas9-mediated genome editing.
Publication
First Author: Casas AI
Year: 2019
Journal: J Clin Invest
Title: Calcium-dependent blood-brain barrier breakdown by NOX5 limits postreperfusion benefit in stroke.
Volume: 129
Issue: 4
Pages: 1772-1778
Publication
First Author: Elbatreek MH
Year: 2020
Journal: PLoS Biol
Title: NOX5-induced uncoupling of endothelial NO synthase is a causal mechanism and theragnostic target of an age-related hypertension endotype.
Volume: 18
Issue: 11
Pages: e3000885
Publication
First Author: Habets PE
Year: 2003
Journal: J Muscle Res Cell Motil
Title: Cardiac expression of Gal4 causes cardiomyopathy in a dose-dependent manner.
Volume: 24
Issue: 2-3
Pages: 205-9
Publication  
First Author: Sivignon A
Year: 2022
Journal: Dis Model Mech
Title: An adherent-invasive Escherichia coli-colonized mouse model to evaluate microbiota-targeting strategies in Crohn's disease.
Volume: 15
Issue: 10
Publication
First Author: Plumb TJ
Year: 1996
Journal: Neurosci Lett
Title: Hypoxanthine-guanine phosphoribosyltransferase (HPRT) expression in the central nervous system of HPRT-deficient mice following adenoviral-mediated gene transfer.
Volume: 214
Issue: 2-3
Pages: 159-62
Publication  
First Author: Arnold WJ
Year: 1973
Journal: Adv Exp Med Biol
Title: Human hypoxanthine-guanine phosphoribosyltransferase (HGPRT): purification and properties.
Volume: 41
Pages: 5-14
Publication
First Author: Ikeda K
Year: 1993
Journal: Enzyme Protein
Title: Postnatal expression of hypoxanthine guanine phosphoribosyltransferase in the mouse brain.
Volume: 47
Issue: 2
Pages: 65-72
Publication
First Author: Guillot PV
Year: 2000
Journal: Physiol Genomics
Title: Targeting of human eNOS promoter to the Hprt locus of mice leads to tissue-restricted transgene expression.
Volume: 2
Issue: 2
Pages: 77-83
Publication
First Author: Cosentino L
Year: 2000
Journal: Mutat Res
Title: Differential mutation of transgenic and endogenous loci in vivo.
Volume: 454
Issue: 1-2
Pages: 1-10
Publication
First Author: Eggan K
Year: 2000
Journal: Science
Title: X-Chromosome inactivation in cloned mouse embryos.
Volume: 290
Issue: 5496
Pages: 1578-81
Publication
First Author: Lo YF
Year: 1979
Journal: Biochem Genet
Title: Developmental expression of murine HPRT. I. Activities, heat stabilities, and electrophoretic mobilities in adult tissues.
Volume: 17
Issue: 7-8
Pages: 737-46
Publication
First Author: Brennand J
Year: 1982
Journal: Proc Natl Acad Sci U S A
Title: Cloned cDNA sequences of the hypoxanthine/guanine phosphoribosyltransferase gene from a mouse neuroblastoma cell line found to have amplified genomic sequences.
Volume: 79
Issue: 6
Pages: 1950-4
Publication
First Author: Lock LF
Year: 1986
Journal: Mol Cell Biol
Title: Methylation of the mouse hprt gene differs on the active and inactive X chromosomes.
Volume: 6
Issue: 3
Pages: 914-24
Publication
First Author: Lyon MF
Year: 1987
Journal: Cytogenet Cell Genet
Title: Localization of the Hprt locus by in situ hybridization and distribution of loci on the mouse X-chromosome.
Volume: 44
Issue: 2-3
Pages: 163-6
Publication
First Author: Johnson GG
Year: 1988
Journal: J Biol Chem
Title: Altered turnover of allelic variants of hypoxanthine phosphoribosyltransferase is associated with N-terminal amino acid sequence variation.
Volume: 263
Issue: 19
Pages: 9079-82
Publication
First Author: Isamat M
Year: 1988
Journal: Somat Cell Mol Genet
Title: Characterization, evolutionary relationships, and chromosome location of processed mouse HPRT pseudogene.
Volume: 14
Issue: 4
Pages: 359-69
Publication
First Author: Magin TM
Year: 1992
Journal: Gene
Title: A position- and orientation-dependent element in the first intron is required for expression of the mouse hprt gene in embryonic stem cells.
Volume: 122
Issue: 2
Pages: 289-96
Publication
First Author: Walker VE
Year: 1993
Journal: Mutat Res
Title: A mouse model for the study of in vivo mutational spectra: sequence specificity of ethylene oxide at the hprt locus.
Volume: 288
Issue: 1
Pages: 151-62
Publication
First Author: Park JG
Year: 1994
Journal: Mol Cell Biol
Title: CpG island promoter region methylation patterns of the inactive-X-chromosome hypoxanthine phosphoribosyltransferase (Hprt) gene.
Volume: 14
Issue: 12
Pages: 7975-83
Publication
First Author: Carlton MB
Year: 1995
Journal: Mamm Genome
Title: Generation of a pseudogene during retroviral infection.
Volume: 6
Issue: 2
Pages: 90-5
Publication
First Author: Kushi A
Year: 1998
Journal: Mamm Genome
Title: Generation of mutant mice with large chromosomal deletion by use of irradiated ES cells--analysis of large deletion around hprt locus of ES cell.
Volume: 9
Issue: 4
Pages: 269-73
Publication
First Author: Vivian JL
Year: 1999
Journal: Biotechniques
Title: Temporal, spatial and tissue-specific expression of a myogenin-lacZ transgene targeted to the Hprt locus in mice.
Volume: 27
Issue: 1
Pages: 154-62
Publication
First Author: Heaney JD
Year: 2004
Journal: Genomics
Title: Tissue-specific expression of a BAC transgene targeted to the Hprt locus in mouse embryonic stem cells.
Volume: 83
Issue: 6
Pages: 1072-82
Publication
First Author: Lewers JC
Year: 2008
Journal: Neuroscience
Title: Consequences of impaired purine recycling in dopaminergic neurons.
Volume: 152
Issue: 3
Pages: 761-72
Publication
First Author: Hendriks G
Year: 2010
Journal: Curr Biol
Title: Transcription-dependent cytosine deamination is a novel mechanism in ultraviolet light-induced mutagenesis.
Volume: 20
Issue: 2
Pages: 170-5
Publication
First Author: Vogel M
Year: 2019
Journal: Stem Cells
Title: HPRT and Purine Salvaging Are Critical for Hematopoietic Stem Cell Function.
Volume: 37
Issue: 12
Pages: 1606-1614
Publication    
First Author: Melton DW
Year: 1987
Title: HPRT gene organization and expression
Volume: 4
Pages: 34-76
Publication
First Author: Wang Z
Year: 2009
Journal: J Biol Chem
Title: Regulation of immature dendritic cell migration by RhoA guanine nucleotide exchange factor Arhgef5.
Volume: 284
Issue: 42
Pages: 28599-606
Publication
First Author: Jörs S
Year: 2010
Journal: PLoS One
Title: Genetic inactivation of Trpml3 does not lead to hearing and vestibular impairment in mice.
Volume: 5
Issue: 12
Pages: e14317
Publication
First Author: Engle SJ
Year: 1996
Journal: Hum Mol Genet
Title: HPRT-APRT-deficient mice are not a model for lesch-nyhan syndrome.
Volume: 5
Issue: 10
Pages: 1607-10
Publication
First Author: Pelz L
Year: 2017
Journal: J Biol Chem
Title: The cell adhesion molecule BT-IgSF is essential for a functional blood-testis barrier and male fertility in mice.
Volume: 292
Issue: 52
Pages: 21490-21503
Publication
First Author: Chen IP
Year: 2009
Journal: J Bone Miner Res
Title: Introduction of a Phe377del mutation in ANK creates a mouse model for craniometaphyseal dysplasia.
Volume: 24
Issue: 7
Pages: 1206-15
Publication
First Author: Borlido J
Year: 2018
Journal: Nat Immunol
Title: Nuclear pore complex-mediated modulation of TCR signaling is required for naïve CD4+ T cell homeostasis.
Volume: 19
Issue: 6
Pages: 594-605
Publication
First Author: Wu CL
Year: 1993
Journal: Nat Genet
Title: Production of a model for Lesch-Nyhan syndrome in hypoxanthine phosphoribosyltransferase-deficient mice.
Volume: 3
Issue: 3
Pages: 235-40
Publication
First Author: Gu JJ
Year: 2000
Journal: J Clin Invest
Title: Inhibition of T lymphocyte activation in mice heterozygous for loss of the IMPDH II gene.
Volume: 106
Issue: 4
Pages: 599-606
Publication
First Author: Peeters SB
Year: 2018
Journal: Hum Mol Genet
Title: Human cis-acting elements regulating escape from X-chromosome inactivation function in mouse.
Volume: 27
Issue: 7
Pages: 1252-1262
Publication
First Author: Jinnah HA
Year: 1991
Journal: Behav Neurosci
Title: Amphetamine-induced behavioral phenotype in a hypoxanthine-guanine phosphoribosyltransferase-deficient mouse model of Lesch-Nyhan syndrome.
Volume: 105
Issue: 6
Pages: 1004-12
Publication
First Author: Varghese S
Year: 2017
Journal: Nucleic Acids Res
Title: In vivo modification of tRNA with an artificial nucleobase leads to full disease remission in an animal model of multiple sclerosis.
Volume: 45
Issue: 4
Pages: 2029-2039
Publication
First Author: Bol SA
Year: 1998
Journal: Cancer Res
Title: Elevated frequencies of benzo(a)pyrene-induced Hprt mutations in internal tissue of XPA-deficient mice.
Volume: 58
Issue: 13
Pages: 2850-6
Publication
First Author: Canalis E
Year: 2016
Journal: J Biol Chem
Title: Hajdu Cheney Mouse Mutants Exhibit Osteopenia, Increased Osteoclastogenesis, and Bone Resorption.
Volume: 291
Issue: 4
Pages: 1538-51
Publication
First Author: Ubelmann F
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Enterocyte loss of polarity and gut wound healing rely upon the F-actin-severing function of villin.
Volume: 110
Issue: 15
Pages: E1380-9
Publication
First Author: Dobrovolsky VN
Year: 1999
Journal: Environ Mol Mutagen
Title: Molecular analysis of in vivo mutations induced by N-ethyl-N-nitrosourea in the autosomal Tk and the X-linked Hprt genes of mouse lymphocytes.
Volume: 34
Issue: 1
Pages: 30-8
Publication
First Author: Yang C
Year: 2012
Journal: Genetics
Title: Targeting of >1.5 Mb of human DNA into the mouse X chromosome reveals presence of cis-acting regulators of epigenetic silencing.
Volume: 192
Issue: 4
Pages: 1281-93
Publication
First Author: Oberdoerffer P
Year: 2005
Journal: Mol Cell Biol
Title: Efficiency of RNA interference in the mouse hematopoietic system varies between cell types and developmental stages.
Volume: 25
Issue: 10
Pages: 3896-905
Publication
First Author: Bartoli M
Year: 2006
Journal: J Biol Chem
Title: A mouse model for monitoring calpain activity under physiological and pathological conditions.
Volume: 281
Issue: 51
Pages: 39672-80
Publication
First Author: Vernet N
Year: 2016
Journal: PLoS One
Title: Mouse Y-Encoded Transcription Factor Zfy2 Is Essential for Sperm Head Remodelling and Sperm Tail Development.
Volume: 11
Issue: 1
Pages: e0145398
Publication
First Author: Vernet N
Year: 2016
Journal: Hum Mol Genet
Title: Zfy genes are required for efficient meiotic sex chromosome inactivation (MSCI) in spermatocytes.
Volume: 25
Issue: 24
Pages: 5300-5310
Publication  
First Author: Hoshina N
Year: 2021
Journal: Science
Title: Female-specific synaptic dysfunction and cognitive impairment in a mouse model of PCDH19 disorder.
Volume: 372
Issue: 6539
Publication
First Author: Lehre AC
Year: 2011
Journal: Epilepsy Res
Title: Deletion of the betaine-GABA transporter (BGT1; slc6a12) gene does not affect seizure thresholds of adult mice.
Volume: 95
Issue: 1-2
Pages: 70-81
Publication
First Author: Mehlmann LM
Year: 2024
Journal: Genesis
Title: Generation and Characterization of a TRIM21 Overexpressing Mouse Line.
Volume: 62
Issue: 5
Pages: e23616
Publication
First Author: Vincent DF
Year: 2010
Journal: Genesis
Title: A rapid strategy to detect the recombined allele in LSL-TβRICA transgenic mice.
Volume: 48
Issue: 9
Pages: 559-62
Publication
First Author: Zong H
Year: 2005
Journal: Cell
Title: Mosaic analysis with double markers in mice.
Volume: 121
Issue: 3
Pages: 479-92
Publication  
First Author: Schmouth JF
Year: 2013
Journal: BMC Biol
Title: Non-coding-regulatory regions of human brain genes delineated by bacterial artificial chromosome knock-in mice.
Volume: 11
Pages: 106
Publication      
First Author: Korecki AJ
Year: 2019
Journal: Genetics
Title: Twenty-Seven Tamoxifen-Inducible iCre-Driver Mouse Strains for Eye and Brain; Including Seventeen Carrying a New Inducible-First Constitutive-Ready Allele.
Publication
First Author: Ghosh M
Year: 2009
Journal: J Clin Invest
Title: Essential role of the RNA-binding protein HuR in progenitor cell survival in mice.
Volume: 119
Issue: 12
Pages: 3530-43
Publication
First Author: Bereshchenko O
Year: 2019
Journal: Clin Epigenetics
Title: Deficiency and haploinsufficiency of histone macroH2A1.1 in mice recapitulate hematopoietic defects of human myelodysplastic syndrome.
Volume: 11
Issue: 1
Pages: 121
Publication
First Author: Jones KB
Year: 2016
Journal: Oncogene
Title: The impact of chromosomal translocation locus and fusion oncogene coding sequence in synovial sarcomagenesis.
Volume: 35
Issue: 38
Pages: 5021-32
Publication
First Author: Winnicka B
Year: 2010
Journal: J Leukoc Biol
Title: CD13 is dispensable for normal hematopoiesis and myeloid cell functions in the mouse.
Volume: 88
Issue: 2
Pages: 347-59
Publication
First Author: Zhu W
Year: 2017
Journal: J Clin Invest
Title: Small GTPase ARF6 controls VEGFR2 trafficking and signaling in diabetic retinopathy.
Volume: 127
Issue: 12
Pages: 4569-4582
Publication
First Author: Casarrubea D
Year: 2013
Journal: J Mol Med (Berl)
Title: Abnormal body iron distribution and erythropoiesis in a novel mouse model with inducible gain of iron regulatory protein (IRP)-1 function.
Volume: 91
Issue: 7
Pages: 871-81
Publication  
First Author: Reinhard JR
Year: 2016
Journal: Nat Commun
Title: The calcium sensor Copine-6 regulates spine structural plasticity and learning and memory.
Volume: 7
Pages: 11613
Publication
First Author: Chen CA
Year: 2020
Journal: Hum Mol Genet
Title: Combination of whole exome sequencing and animal modeling identifies TMPRSS9 as a candidate gene for autism spectrum disorder.
Volume: 29
Issue: 3
Pages: 459-470
Publication
First Author: Arbogast T
Year: 2017
Journal: PLoS Genet
Title: Mouse models of 17q21.31 microdeletion and microduplication syndromes highlight the importance of Kansl1 for cognition.
Volume: 13
Issue: 7
Pages: e1006886
Publication
First Author: Contreras X
Year: 2021
Journal: Cell Rep
Title: A genome-wide library of MADM mice for single-cell genetic mosaic analysis.
Volume: 35
Issue: 12
Pages: 109274
Publication
First Author: Gabel LA
Year: 2011
Journal: Genes Brain Behav
Title: Mutation of the dyslexia-associated gene Dcdc2 impairs LTM and visuo-spatial performance in mice.
Volume: 10
Issue: 8
Pages: 868-75
Publication  
First Author: Eblimit A
Year: 2018
Journal: Exp Eye Res
Title: NMNAT1 E257K variant, associated with Leber Congenital Amaurosis (LCA9), causes a mild retinal degeneration phenotype.
Volume: 173
Pages: 32-43
Publication  
First Author: Vilmundarson RO
Year: 2022
Journal: Front Immunol
Title: Savior Siblings Might Rescue Fetal Lethality But Not Adult Lymphoma in Irf2bp2-Null Mice.
Volume: 13
Pages: 868053
Publication
First Author: Li K
Year: 2014
Journal: Int J Clin Exp Pathol
Title: DSTYK kinase domain ablation impaired the mice capabilities of learning and memory in water maze test.
Volume: 7
Issue: 10
Pages: 6486-92
Publication  
First Author: Chalise JP
Year: 2023
Journal: Front Immunol
Title: ARID5B regulates fatty acid metabolism and proliferation at the Pre-B cell stage during B cell development.
Volume: 14
Pages: 1170475
Publication    
First Author: Coyne LP
Year: 2023
Journal: Elife
Title: Mitochondrial protein import clogging as a mechanism of disease.
Volume: 12
Publication
First Author: McMahon A
Year: 2011
Journal: J Lipid Res
Title: Epidermal expression of an Elovl4 transgene rescues neonatal lethality of homozygous Stargardt disease-3 mice.
Volume: 52
Issue: 6
Pages: 1128-38
Publication
First Author: Gamiotea-Turro D
Year: 2023
Journal: Purinergic Signal
Title: Transcriptomic analysis reveals novel age-independent immunomodulatory proteins as a mode of cerebroprotection in P2X4 receptor knockout mice after ischemic stroke.
Volume: 19
Issue: 3
Pages: 489-500
Publication  
First Author: McMahon A
Year: 2007
Journal: Mol Vis
Title: Retinal pathology and skin barrier defect in mice carrying a Stargardt disease-3 mutation in elongase of very long chain fatty acids-4.
Volume: 13
Pages: 258-72
Publication
First Author: Winkelmann A
Year: 2014
Journal: J Clin Invest
Title: Changes in neural network homeostasis trigger neuropsychiatric symptoms.
Volume: 124
Issue: 2
Pages: 696-711
Publication
First Author: Çaliskan G
Year: 2016
Journal: Cereb Cortex
Title: Identification of Parvalbumin Interneurons as Cellular Substrate of Fear Memory Persistence.
Volume: 26
Issue: 5
Pages: 2325-2340
Publication
First Author: Brewer MK
Year: 2024
Journal: J Neurochem
Title: Glycogen accumulation modulates life span in a mouse model of amyotrophic lateral sclerosis.
Volume: 168
Issue: 5
Pages: 744-759
Publication
First Author: Schaffer AE
Year: 2011
Journal: Mol Endocrinol
Title: Transgenic overexpression of the transcription factor Nkx6.1 in β-cells of mice does not increase β-cell proliferation, β-cell mass, or improve glucose clearance.
Volume: 25
Issue: 11
Pages: 1904-14
Publication
First Author: Redhead NJ
Year: 1996
Journal: Hum Gene Ther
Title: Mice with adenine phosphoribosyltransferase deficiency develop fatal 2,8-dihydroxyadenine lithiasis.
Volume: 7
Issue: 13
Pages: 1491-502
Publication
First Author: Minami T
Year: 2009
Journal: J Clin Invest
Title: The Down syndrome critical region gene 1 short variant promoters direct vascular bed-specific gene expression during inflammation in mice.
Volume: 119
Issue: 8
Pages: 2257-70
Publication
First Author: Baek KH
Year: 2009
Journal: Nature
Title: Down's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1.
Volume: 459
Issue: 7250
Pages: 1126-30
Publication
First Author: Cadieux C
Year: 2006
Journal: Cancer Res
Title: Transgenic mice expressing the p75 CCAAT-displacement protein/Cut homeobox isoform develop a myeloproliferative disease-like myeloid leukemia.
Volume: 66
Issue: 19
Pages: 9492-501
Publication
First Author: Dutta RK
Year: 2017
Journal: J Am Soc Nephrol
Title: Beneficial Effects of Myo-Inositol Oxygenase Deficiency in Cisplatin-Induced AKI.
Volume: 28
Issue: 5
Pages: 1421-1436
Publication
First Author: Schliekelman M
Year: 2009
Journal: Cancer Res
Title: Impaired Bub1 function in vivo compromises tension-dependent checkpoint function leading to aneuploidy and tumorigenesis.
Volume: 69
Issue: 1
Pages: 45-54
Publication
First Author: Perez-Frances M
Year: 2021
Journal: Nat Commun
Title: Pancreatic Ppy-expressing γ-cells display mixed phenotypic traits and the adaptive plasticity to engage insulin production.
Volume: 12
Issue: 1
Pages: 4458
Publication    
First Author: Damond N
Year: 2016
Journal: Elife
Title: Blockade of glucagon signaling prevents or reverses diabetes onset only if residual β-cells persist.
Volume: 5