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Search results 101 to 200 out of 570 for Insr

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Categories

Category: Publication
Type Details Score
Publication
First Author: Emanuelli B
Year: 2014
Journal: J Clin Invest
Title: Interplay between FGF21 and insulin action in the liver regulates metabolism.
Volume: 124
Issue: 2
Pages: 515-27
Publication
First Author: El Ouaamari A
Year: 2013
Journal: Cell Rep
Title: Liver-derived systemic factors drive β cell hyperplasia in insulin-resistant states.
Volume: 3
Issue: 2
Pages: 401-10
Publication
First Author: Fisher SJ
Year: 2003
Journal: J Clin Invest
Title: Insulin signaling is required for insulin's direct and indirect action on hepatic glucose production.
Volume: 111
Issue: 4
Pages: 463-8
Publication
First Author: Biddinger SB
Year: 2008
Journal: Cell Metab
Title: Hepatic insulin resistance is sufficient to produce dyslipidemia and susceptibility to atherosclerosis.
Volume: 7
Issue: 2
Pages: 125-34
Publication
First Author: Haas JT
Year: 2012
Journal: Cell Metab
Title: Hepatic insulin signaling is required for obesity-dependent expression of SREBP-1c mRNA but not for feeding-dependent expression.
Volume: 15
Issue: 6
Pages: 873-84
Publication  
First Author: Styskal J
Year: 2013
Journal: Free Radic Biol Med
Title: Methionine sulfoxide reductase A affects insulin resistance by protecting insulin receptor function.
Volume: 56
Pages: 123-32
Publication
First Author: Blüher M
Year: 2003
Journal: Science
Title: Extended longevity in mice lacking the insulin receptor in adipose tissue.
Volume: 299
Issue: 5606
Pages: 572-4
Publication
First Author: Blüher M
Year: 2004
Journal: J Biol Chem
Title: Role of insulin action and cell size on protein expression patterns in adipocytes.
Volume: 279
Issue: 30
Pages: 31902-9
Publication
First Author: Blüher M
Year: 2004
Journal: J Biol Chem
Title: Intrinsic heterogeneity in adipose tissue of fat-specific insulin receptor knock-out mice is associated with differences in patterns of gene expression.
Volume: 279
Issue: 30
Pages: 31891-901
Publication
First Author: Lopez-Izquierdo A
Year: 2014
Journal: Am J Physiol Heart Circ Physiol
Title: The absence of insulin signaling in the heart induces changes in potassium channel expression and ventricular repolarization.
Volume: 306
Issue: 5
Pages: H747-54
Publication
First Author: Symons JD
Year: 2011
Journal: Am J Physiol Heart Circ Physiol
Title: Knockout of insulin receptors in cardiomyocytes attenuates coronary arterial dysfunction induced by pressure overload.
Volume: 300
Issue: 1
Pages: H374-81
Publication
First Author: Griesel BA
Year: 2010
Journal: Diabetes
Title: Acute inhibition of fatty acid import inhibits GLUT4 transcription in adipose tissue, but not skeletal or cardiac muscle tissue, partly through liver X receptor (LXR) signaling.
Volume: 59
Issue: 4
Pages: 800-7
Publication
First Author: Boudina S
Year: 2009
Journal: Circulation
Title: Contribution of impaired myocardial insulin signaling to mitochondrial dysfunction and oxidative stress in the heart.
Volume: 119
Issue: 9
Pages: 1272-83
Publication
First Author: Belke DD
Year: 2002
Journal: J Clin Invest
Title: Insulin signaling coordinately regulates cardiac size, metabolism, and contractile protein isoform expression.
Volume: 109
Issue: 5
Pages: 629-39
Publication
First Author: Ealey KN
Year: 2008
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Reduced susceptibility of muscle-specific insulin receptor knockout mice to colon carcinogenesis.
Volume: 294
Issue: 3
Pages: G679-86
Publication
First Author: Yechoor VK
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Distinct pathways of insulin-regulated versus diabetes-regulated gene expression: an in vivo analysis in MIRKO mice.
Volume: 101
Issue: 47
Pages: 16525-30
Publication
First Author: Hu P
Year: 2003
Journal: Am J Physiol Heart Circ Physiol
Title: Minimally invasive aortic banding in mice: effects of altered cardiomyocyte insulin signaling during pressure overload.
Volume: 285
Issue: 3
Pages: H1261-9
Publication
First Author: Kim JK
Year: 2000
Journal: J Clin Invest
Title: Redistribution of substrates to adipose tissue promotes obesity in mice with selective insulin resistance in muscle.
Volume: 105
Issue: 12
Pages: 1791-7
Publication
First Author: Wojtaszewski JF
Year: 1999
Journal: J Clin Invest
Title: Exercise modulates postreceptor insulin signaling and glucose transport in muscle-specific insulin receptor knockout mice.
Volume: 104
Issue: 9
Pages: 1257-64
Publication
First Author: Guerra C
Year: 2001
Journal: J Clin Invest
Title: Brown adipose tissue-specific insulin receptor knockout shows diabetic phenotype without insulin resistance.
Volume: 108
Issue: 8
Pages: 1205-13
Publication
First Author: Kumari M
Year: 2019
Journal: J Cell Biochem
Title: Deletion of insulin receptor in the proximal tubule and fasting augment albumin excretion.
Volume: 120
Issue: 6
Pages: 10688-10696
Publication
First Author: Merry TL
Year: 2020
Journal: Nat Commun
Title: Partial impairment of insulin receptor expression mimics fasting to prevent diet-induced fatty liver disease.
Volume: 11
Issue: 1
Pages: 2080
Publication
First Author: Cai W
Year: 2018
Journal: J Clin Invest
Title: Insulin regulates astrocyte gliotransmission and modulates behavior.
Volume: 128
Issue: 7
Pages: 2914-2926
Publication  
First Author: Tarchick MJ
Year: 2019
Journal: Exp Eye Res
Title: Endogenous insulin signaling in the RPE contributes to the maintenance of rod photoreceptor function in diabetes.
Volume: 180
Pages: 63-74
Publication
First Author: Gómez-Hernández A
Year: 2016
Journal: Endocrinology
Title: Severe Brown Fat Lipoatrophy Aggravates Atherosclerotic Process in Male Mice.
Volume: 157
Issue: 9
Pages: 3517-28
Publication
First Author: Fowlkes JL
Year: 2020
Journal: Sci Rep
Title: Postnatal loss of the insulin receptor in osteoprogenitor cells does not impart a metabolic phenotype.
Volume: 10
Issue: 1
Pages: 8842
Publication
First Author: Hausen AC
Year: 2016
Journal: Cell Rep
Title: Insulin-Dependent Activation of MCH Neurons Impairs Locomotor Activity and Insulin Sensitivity in Obesity.
Volume: 17
Issue: 10
Pages: 2512-2521
Publication
First Author: Rajala RV
Year: 2009
Journal: J Neurochem
Title: Insulin receptor signaling regulates actin cytoskeletal organization in developing photoreceptors.
Volume: 110
Issue: 5
Pages: 1648-60
Publication
First Author: Qiang G
Year: 2016
Journal: Mol Metab
Title: Lipodystrophy and severe metabolic dysfunction in mice with adipose tissue-specific insulin receptor ablation.
Volume: 5
Issue: 7
Pages: 480-490
Publication  
First Author: Nizar JM
Year: 2018
Journal: JCI Insight
Title: Renal tubule insulin receptor modestly promotes elevated blood pressure and markedly stimulates glucose reabsorption.
Volume: 3
Issue: 16
Publication
First Author: Sotiropoulos KB
Year: 2006
Journal: FASEB J
Title: Adipose-specific effect of rosiglitazone on vascular permeability and protein kinase C activation: novel mechanism for PPARgamma agonist's effects on edema and weight gain.
Volume: 20
Issue: 8
Pages: 1203-5
Publication
First Author: Tiwari S
Year: 2013
Journal: J Am Soc Nephrol
Title: Deletion of the insulin receptor in the proximal tubule promotes hyperglycemia.
Volume: 24
Issue: 8
Pages: 1209-14
Publication
First Author: Jensen SR
Year: 2017
Journal: Endocrinology
Title: Quantitative Proteomics of Intestinal Mucosa From Male Mice Lacking Intestinal Epithelial Insulin Receptors.
Volume: 158
Issue: 8
Pages: 2470-2485
Publication
First Author: Cabrae R
Year: 2020
Journal: Sci Rep
Title: Insulin activates hepatic Wnt/β-catenin signaling through stearoyl-CoA desaturase 1 and Porcupine.
Volume: 10
Issue: 1
Pages: 5186
Publication
First Author: Konishi M
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Endothelial insulin receptors differentially control insulin signaling kinetics in peripheral tissues and brain of mice.
Volume: 114
Issue: 40
Pages: E8478-E8487
Publication
First Author: Ock S
Year: 2011
Journal: Endocr J
Title: Conditional deletion of insulin receptor in thyrocytes does not affect thyroid structure and function.
Volume: 58
Issue: 11
Pages: 1013-9
Publication
First Author: Shin AC
Year: 2014
Journal: Cell Metab
Title: Brain insulin lowers circulating BCAA levels by inducing hepatic BCAA catabolism.
Volume: 20
Issue: 5
Pages: 898-909
Publication
First Author: Könner AC
Year: 2007
Journal: Cell Metab
Title: Insulin action in AgRP-expressing neurons is required for suppression of hepatic glucose production.
Volume: 5
Issue: 6
Pages: 438-49
Publication
First Author: Wu S
Year: 2014
Journal: Diabetes
Title: Obesity-induced infertility and hyperandrogenism are corrected by deletion of the insulin receptor in the ovarian theca cell.
Volume: 63
Issue: 4
Pages: 1270-82
Publication
First Author: Wu M
Year: 2022
Journal: Nat Commun
Title: Functionally selective signaling and broad metabolic benefits by novel insulin receptor partial agonists.
Volume: 13
Issue: 1
Pages: 942
Publication  
First Author: Lee HJ
Year: 2021
Journal: JCI Insight
Title: Proximal tubular epithelial insulin receptor mediates high-fat diet-induced kidney injury.
Volume: 6
Issue: 3
Publication
First Author: Jensen SR
Year: 2017
Journal: Endocrinology
Title: Elucidating the Biological Roles of Insulin and Its Receptor in Murine Intestinal Growth and Function.
Volume: 158
Issue: 8
Pages: 2453-2469
Publication
First Author: Tiwari S
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Impaired sodium excretion and increased blood pressure in mice with targeted deletion of renal epithelial insulin receptor.
Volume: 105
Issue: 17
Pages: 6469-74
Publication
First Author: Fougeray T
Year: 2022
Journal: Cell Rep
Title: The hepatocyte insulin receptor is required to program the liver clock and rhythmic gene expression.
Volume: 39
Issue: 2
Pages: 110674
Publication  
First Author: Calco GN
Year: 2022
Journal: JCI Insight
Title: Insulin increases sensory nerve density and reflex bronchoconstriction in obese mice.
Volume: 7
Issue: 20
Publication
First Author: Kavazović I
Year: 2022
Journal: Diabetes
Title: Hyperglycemia and Not Hyperinsulinemia Mediates Diabetes-Induced Memory CD8 T-Cell Dysfunction.
Volume: 71
Issue: 4
Pages: 706-721
Publication
First Author: Tsai S
Year: 2018
Journal: Cell Metab
Title: Insulin Receptor-Mediated Stimulation Boosts T Cell Immunity during Inflammation and Infection.
Volume: 28
Issue: 6
Pages: 922-934.e4
Publication
First Author: Niitsu Y
Year: 2023
Journal: PLoS One
Title: Increased serum extracellular vesicle miR-144-3p and miR-486a-3p in a mouse model of adipose tissue regeneration promote hepatocyte proliferation by targeting Txnip.
Volume: 18
Issue: 5
Pages: e0284989
Publication
First Author: Rajala A
Year: 2008
Journal: J Biol Chem
Title: Loss of neuroprotective survival signal in mice lacking insulin receptor gene in rod photoreceptor cells.
Volume: 283
Issue: 28
Pages: 19781-92
Publication
First Author: Blüher M
Year: 2002
Journal: Dev Cell
Title: Adipose tissue selective insulin receptor knockout protects against obesity and obesity-related glucose intolerance.
Volume: 3
Issue: 1
Pages: 25-38
Publication
First Author: Moore SF
Year: 2015
Journal: Cardiovasc Res
Title: Loss of the insulin receptor in murine megakaryocytes/platelets causes thrombocytosis and alterations in IGF signalling.
Volume: 107
Issue: 1
Pages: 9-19
Publication
First Author: Studentsova V
Year: 2018
Journal: Sci Rep
Title: Obesity/Type II Diabetes Promotes Function-limiting Changes in Murine Tendons that are not reversed by Restoring Normal Metabolic Function.
Volume: 8
Issue: 1
Pages: 9218
Publication
First Author: Munoz MD
Year: 2023
Journal: Sci Rep
Title: Activation of brown adipose tissue by a low-protein diet ameliorates hyperglycemia in a diabetic lipodystrophy mouse model.
Volume: 13
Issue: 1
Pages: 11808
Publication
First Author: Andres SF
Year: 2015
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Deletion of intestinal epithelial insulin receptor attenuates high-fat diet-induced elevations in cholesterol and stem, enteroendocrine, and Paneth cell mRNAs.
Volume: 308
Issue: 2
Pages: G100-11
Publication
First Author: Katic M
Year: 2007
Journal: Aging Cell
Title: Mitochondrial gene expression and increased oxidative metabolism: role in increased lifespan of fat-specific insulin receptor knock-out mice.
Volume: 6
Issue: 6
Pages: 827-39
Publication  
First Author: Thrailkill K
Year: 2014
Journal: J Diabetes Res
Title: Loss of insulin receptor in osteoprogenitor cells impairs structural strength of bone.
Volume: 2014
Pages: 703589
Publication  
First Author: Shankar K
Year: 2021
Journal: JCI Insight
Title: Ghrelin cell-expressed insulin receptors mediate meal- and obesity-induced declines in plasma ghrelin.
Volume: 6
Issue: 18
Publication
First Author: Shin AC
Year: 2017
Journal: Diabetes
Title: Insulin Receptor Signaling in POMC, but Not AgRP, Neurons Controls Adipose Tissue Insulin Action.
Volume: 66
Issue: 6
Pages: 1560-1571
Publication
First Author: Vicent D
Year: 2003
Journal: J Clin Invest
Title: The role of endothelial insulin signaling in the regulation of vascular tone and insulin resistance.
Volume: 111
Issue: 9
Pages: 1373-80
Publication  
First Author: Wu S
Year: 2019
Journal: Bone
Title: The effect of a high-calorie diet on bone growth is mediated by the insulin receptor.
Volume: 122
Pages: 166-175
Publication
First Author: Brothers KJ
Year: 2010
Journal: Cell Metab
Title: Rescue of obesity-induced infertility in female mice due to a pituitary-specific knockout of the insulin receptor.
Volume: 12
Issue: 3
Pages: 295-305
Publication  
First Author: Cai W
Year: 2017
Journal: Nat Commun
Title: Domain-dependent effects of insulin and IGF-1 receptors on signalling and gene expression.
Volume: 8
Pages: 14892
Publication
First Author: Klöckener T
Year: 2011
Journal: Nat Neurosci
Title: High-fat feeding promotes obesity via insulin receptor/PI3K-dependent inhibition of SF-1 VMH neurons.
Volume: 14
Issue: 7
Pages: 911-8
Publication  
First Author: Oakie A
Year: 2020
Journal: Mol Cell Endocrinol
Title: Postnatal knockout of beta cell insulin receptor impaired insulin secretion in male mice exposed to high-fat diet stress.
Volume: 499
Pages: 110588
Publication
First Author: Merry TL
Year: 2017
Journal: Aging Cell
Title: Impairment of insulin signalling in peripheral tissue fails to extend murine lifespan.
Volume: 16
Issue: 4
Pages: 761-772
Publication
First Author: Gómez-Hernández A
Year: 2013
Journal: Endocrinology
Title: Implication of insulin receptor A isoform and IRA/IGF-IR hybrid receptors in the aortic vascular smooth muscle cell proliferation: role of TNF-α and IGF-II.
Volume: 154
Issue: 7
Pages: 2352-64
Publication
First Author: Wu S
Year: 2012
Journal: Diabetes
Title: Reproductive tissues maintain insulin sensitivity in diet-induced obesity.
Volume: 61
Issue: 1
Pages: 114-23
Publication
First Author: DiVall SA
Year: 2015
Journal: PLoS One
Title: Insulin receptor signaling in the GnRH neuron plays a role in the abnormal GnRH pulsatility of obese female mice.
Volume: 10
Issue: 3
Pages: e0119995
Publication
First Author: Gómez-Hernández A
Year: 2012
Journal: Endocrinology
Title: Brown fat lipoatrophy and increased visceral adiposity through a concerted adipocytokines overexpression induces vascular insulin resistance and dysfunction.
Volume: 153
Issue: 3
Pages: 1242-55
Publication
First Author: Manaserh IH
Year: 2019
Journal: PLoS Biol
Title: Ablating astrocyte insulin receptors leads to delayed puberty and hypogonadism in mice.
Volume: 17
Issue: 3
Pages: e3000189
Publication  
First Author: Warmke N
Year: 2024
Journal: Biochem Biophys Res Commun
Title: Insulin receptor signalling in PDGFRβ-expressing cells influences systemic metabolism and negatively impacts lipid storage.
Volume: 735
Pages: 150799
Publication  
First Author: Woodruff ML
Year: 2015
Journal: Sci Rep
Title: Effect of knocking down the insulin receptor on mouse rod responses.
Volume: 5
Pages: 7858
Publication
First Author: Friesen M
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Adipocyte insulin receptor activity maintains adipose tissue mass and lifespan.
Volume: 476
Issue: 4
Pages: 487-492
Publication
First Author: McQueen AP
Year: 2005
Journal: J Mol Cell Cardiol
Title: Contractile dysfunction in hypertrophied hearts with deficient insulin receptor signaling: possible role of reduced capillary density.
Volume: 39
Issue: 6
Pages: 882-92
Publication
First Author: Wang G
Year: 2020
Journal: Diabetes
Title: Muscle-Specific Insulin Receptor Overexpression Protects Mice From Diet-Induced Glucose Intolerance but Leads to Postreceptor Insulin Resistance.
Volume: 69
Issue: 11
Pages: 2294-2309
Publication
First Author: Ogino J
Year: 2006
Journal: J Endocrinol
Title: Insulin resistance and increased pancreatic beta-cell proliferation in mice expressing a mutant insulin receptor (P1195L).
Volume: 190
Issue: 3
Pages: 739-47
Publication  
First Author: Lee EY
Year: 2015
Journal: Sci Rep
Title: Unsuppressed lipolysis in adipocytes is linked with enhanced gluconeogenesis and altered bile acid physiology in Insr(P1195L/+) mice fed high-fat-diet.
Volume: 5
Pages: 17565
Publication
First Author: Sabapathy T
Year: 2022
Journal: Biochim Biophys Acta Mol Basis Dis
Title: High-fat diet induced alterations in plasma membrane cholesterol content impairs insulin receptor binding and signalling in mouse liver but is ameliorated by atorvastatin.
Volume: 1868
Issue: 6
Pages: 166372
Publication
First Author: Moodie SA
Year: 1999
Journal: J Biol Chem
Title: Identification of the APS protein as a novel insulin receptor substrate.
Volume: 274
Issue: 16
Pages: 11186-93
Publication
First Author: Lee J
Year: 1994
Journal: Am J Physiol
Title: The insulin receptor: structure, function, and signaling.
Volume: 266
Issue: 2 Pt 1
Pages: C319-34
Publication
First Author: Taylor SI
Year: 1999
Journal: Cell
Title: Deconstructing type 2 diabetes.
Volume: 97
Issue: 1
Pages: 9-12
Publication
First Author: Yip CC
Year: 2003
Journal: J Biol Chem
Title: Three-dimensional structural interactions of insulin and its receptor.
Volume: 278
Issue: 30
Pages: 27329-32
Publication
First Author: Acevedo N
Year: 2007
Journal: Biol Reprod
Title: Insulin signaling in mouse oocytes.
Volume: 77
Issue: 5
Pages: 872-9
Publication
First Author: Nandi A
Year: 2010
Journal: Endocrinology
Title: The effect of insulin signaling on female reproductive function independent of adiposity and hyperglycemia.
Volume: 151
Issue: 4
Pages: 1863-71
Publication  
First Author: Escribano O
Year: 2015
Journal: Mol Cell Endocrinol
Title: Insulin receptor isoform A confers a higher proliferative capability to pancreatic beta cells enabling glucose availability and IGF-I signaling.
Volume: 409
Pages: 82-91
Publication
First Author: Sengupta A
Year: 2018
Journal: Endocrinology
Title: Endothelial Insulin Receptor Restoration Rescues Vascular Function in Male Insulin Receptor Haploinsufficient Mice.
Volume: 159
Issue: 8
Pages: 2917-2925
Publication  
First Author: Lopez-Pastor AR
Year: 2019
Journal: Dis Model Mech
Title: Liver-specific insulin receptor isoform A expression enhances hepatic glucose uptake and ameliorates liver steatosis in a mouse model of diet-induced obesity.
Volume: 12
Issue: 2
Publication
First Author: Accili D
Year: 1997
Journal: Trends Endocrinol Metab
Title: Insulin receptor knock-out mice.
Volume: 8
Issue: 3
Pages: 101-4
Publication
First Author: Chen W
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Loss of insulin signaling in astrocytes exacerbates Alzheimer-like phenotypes in a 5xFAD mouse model.
Volume: 120
Issue: 21
Pages: e2220684120
Publication
First Author: Aga-Mizrachi S
Year: 2008
Journal: Endocrinology
Title: Cytosolic protein tyrosine phosphatase-epsilon is a negative regulator of insulin signaling in skeletal muscle.
Volume: 149
Issue: 2
Pages: 605-14
Publication
First Author: Tseng LT
Year: 2013
Journal: J Biol Chem
Title: LMBD1 protein serves as a specific adaptor for insulin receptor internalization.
Volume: 288
Issue: 45
Pages: 32424-32
Publication
First Author: Mori K
Year: 2005
Journal: Mol Cell Endocrinol
Title: Distinct Grb10 domain requirements for effects on glucose uptake and insulin signaling.
Volume: 230
Issue: 1-2
Pages: 39-50
Publication
First Author: El Ouaamari A
Year: 2016
Journal: Cell Metab
Title: SerpinB1 Promotes Pancreatic β Cell Proliferation.
Volume: 23
Issue: 1
Pages: 194-205
Publication
First Author: Galic S
Year: 2003
Journal: Mol Cell Biol
Title: Regulation of insulin receptor signaling by the protein tyrosine phosphatase TCPTP.
Volume: 23
Issue: 6
Pages: 2096-108
Publication
First Author: Schmidt V
Year: 2016
Journal: J Clin Invest
Title: SORLA facilitates insulin receptor signaling in adipocytes and exacerbates obesity.
Volume: 126
Issue: 7
Pages: 2706-20
Publication
First Author: Fiory F
Year: 2005
Journal: Mol Cell Biol
Title: Tyrosine phosphorylation of phosphoinositide-dependent kinase 1 by the insulin receptor is necessary for insulin metabolic signaling.
Volume: 25
Issue: 24
Pages: 10803-14
Publication
First Author: Pires KM
Year: 2019
Journal: Antioxid Redox Signal
Title: Suppression of Cardiac Autophagy by Hyperinsulinemia in Insulin Receptor-Deficient Hearts Is Mediated by Insulin-Like Growth Factor Receptor Signaling.
Volume: 31
Issue: 6
Pages: 444-457
Publication
First Author: Nevado C
Year: 2006
Journal: Endocrinology
Title: Role of insulin receptor in the regulation of glucose uptake in neonatal hepatocytes.
Volume: 147
Issue: 8
Pages: 3709-18
Publication
First Author: Matsumoto M
Year: 2007
Journal: Cell Metab
Title: Impaired regulation of hepatic glucose production in mice lacking the forkhead transcription factor Foxo1 in liver.
Volume: 6
Issue: 3
Pages: 208-16
Publication
First Author: Nelson JF
Year: 2012
Journal: J Gerontol A Biol Sci Med Sci
Title: Probing the relationship between insulin sensitivity and longevity using genetically modified mice.
Volume: 67
Issue: 12
Pages: 1332-8