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Search results 101 to 200 out of 329 for Keap1

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Category: Publication
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Type Details Score
Publication
28507037 | J:244632
 
First Author: Suzuki T
Year: 2017
Journal: Mol Cell Biol
Title: Systemic Activation of NRF2 Alleviates Lethal Autoimmune Inflammation in Scurfy Mice.
Volume: 37
Issue: 15
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Publication
18687751 | J:142149
First Author: Okada K
Year: 2008
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Ursodeoxycholic acid stimulates Nrf2-mediated hepatocellular transport, detoxification, and antioxidative stress systems in mice.
Volume: 295
Issue: 4
Pages: G735-47
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Publication
24379438 | J:271368
First Author: Taguchi K
Year: 2014
Journal: Mol Cell Biol
Title: Nrf2 enhances cholangiocyte expansion in Pten-deficient livers.
Volume: 34
Issue: 5
Pages: 900-13
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Publication
28055010 | J:329111
First Author: Ugun-Klusek A
Year: 2017
Journal: Cell Death Dis
Title: Continued 26S proteasome dysfunction in mouse brain cortical neurons impairs autophagy and the Keap1-Nrf2 oxidative defence pathway.
Volume: 8
Issue: 1
Pages: e2531
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Publication
34087234 | J:307300
First Author: Liu Y
Year: 2021
Journal: J Biol Chem
Title: Loss of PKA regulatory subunit 1α aggravates cardiomyocyte necrosis and myocardial ischemia/reperfusion injury.
Volume: 297
Issue: 1
Pages: 100850
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Publication
24486487 | J:219149
First Author: Li B
Year: 2014
Journal: Biochem Biophys Res Commun
Title: Dihydro-CDDO-trifluoroethyl amide suppresses inflammatory responses in macrophages via activation of Nrf2.
Volume: 444
Issue: 4
Pages: 555-61
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Publication
28515152 | J:247710
First Author: Sakai E
Year: 2017
Journal: FASEB J
Title: Effects of deficiency of Kelch-like ECH-associated protein 1 on skeletal organization: a mechanism for diminished nuclear factor of activated T cells cytoplasmic 1 during osteoclastogenesis.
Volume: 31
Issue: 9
Pages: 4011-4022
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Publication
15087497 | J:89567
First Author: Motohashi H
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Small Maf proteins serve as transcriptional cofactors for keratinocyte differentiation in the Keap1-Nrf2 regulatory pathway.
Volume: 101
Issue: 17
Pages: 6379-84
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Publication
16872277 | J:116009
First Author: Zhang Y
Year: 2006
Journal: Biochem J
Title: Negative regulation of the Nrf1 transcription factor by its N-terminal domain is independent of Keap1: Nrf1, but not Nrf2, is targeted to the endoplasmic reticulum.
Volume: 399
Issue: 3
Pages: 373-85
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Publication
35668451 | J:325538
First Author: Zhao W
Year: 2022
Journal: J Neuroinflammation
Title: Astrocytic Nrf2 expression protects spinal cord from oxidative stress following spinal cord injury in a male mouse model.
Volume: 19
Issue: 1
Pages: 134
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Publication
31181253 | J:294149
 
First Author: Ma A
Year: 2019
Journal: Free Radic Biol Med
Title: Upregulating Nrf2 in the RVLM ameliorates sympatho-excitation in mice with chronic heart failure.
Volume: 141
Pages: 84-92
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Publication
30995469 | J:284339
First Author: Pyaram K
Year: 2019
Journal: Cell Rep
Title: Keap1-Nrf2 System Plays an Important Role in Invariant Natural Killer T Cell Development and Homeostasis.
Volume: 27
Issue: 3
Pages: 699-707.e4
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Publication
37062029 | J:336554
First Author: DeBlasi JM
Year: 2023
Journal: Cancer Res
Title: Distinct Nrf2 Signaling Thresholds Mediate Lung Tumor Initiation and Progression.
Volume: 83
Issue: 12
Pages: 1953-1967
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Publication
36243294 | J:330375
 
First Author: Dionne G
Year: 2022
Journal: Gene Expr Patterns
Title: Expression and localization of NRF2/Keap1 signalling pathway genes in mouse preimplantation embryos exposed to free fatty acids.
Volume: 46
Pages: 119281
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Publication
20404090 | J:162676
First Author: Taguchi K
Year: 2010
Journal: Mol Cell Biol
Title: Genetic analysis of cytoprotective functions supported by graded expression of Keap1.
Volume: 30
Issue: 12
Pages: 3016-26
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Publication
12151510 | J:78097
First Author: Kotilinek LA
Year: 2002
Journal: J Neurosci
Title: Reversible memory loss in a mouse transgenic model of Alzheimer's disease.
Volume: 22
Issue: 15
Pages: 6331-5
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Publication
26293820 | J:290689
First Author: Noel S
Year: 2015
Journal: J Am Soc Nephrol
Title: T Lymphocyte-Specific Activation of Nrf2 Protects from AKI.
Volume: 26
Issue: 12
Pages: 2989-3000
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Publication
33318486 | J:303385
First Author: Oishi T
Year: 2020
Journal: NPJ Aging Mech Dis
Title: Activation of the NRF2 pathway in Keap1-knockdown mice attenuates progression of age-related hearing loss.
Volume: 6
Issue: 1
Pages: 14
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Publication
24224011 | J:209321
First Author: Xu J
Year: 2013
Journal: PLoS One
Title: Keap1-knockdown decreases fasting-induced fatty liver via altered lipid metabolism and decreased fatty acid mobilization from adipose tissue.
Volume: 8
Issue: 11
Pages: e79841
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Publication
19001094 | J:144764
First Author: Kobayashi M
Year: 2009
Journal: Mol Cell Biol
Title: The antioxidant defense system Keap1-Nrf2 comprises a multiple sensing mechanism for responding to a wide range of chemical compounds.
Volume: 29
Issue: 2
Pages: 493-502
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Publication
22448038 | J:197808
First Author: Kaspar JW
Year: 2012
Journal: J Cell Sci
Title: Antioxidant-induced INrf2 (Keap1) tyrosine 85 phosphorylation controls the nuclear export and degradation of the INrf2-Cul3-Rbx1 complex to allow normal Nrf2 activation and repression.
Volume: 125
Issue: Pt 4
Pages: 1027-38
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Publication
22808024 | J:189635
First Author: Wu KC
Year: 2012
Journal: PLoS One
Title: Effect of graded Nrf2 activation on phase-I and -II drug metabolizing enzymes and transporters in mouse liver.
Volume: 7
Issue: 7
Pages: e39006
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Publication
22677785 | J:186162
First Author: Wu KC
Year: 2012
Journal: Toxicol Appl Pharmacol
Title: Nrf2 activation prevents cadmium-induced acute liver injury.
Volume: 263
Issue: 1
Pages: 14-20
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Publication
22627062 | J:186170
First Author: Wu KC
Year: 2012
Journal: Toxicol Appl Pharmacol
Title: Role of Nrf2 in preventing ethanol-induced oxidative stress and lipid accumulation.
Volume: 262
Issue: 3
Pages: 321-9
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Publication
24667526 | J:215055
First Author: Lu YF
Year: 2014
Journal: PLoS One
Title: Overexpression of Nrf2 protects against microcystin-induced hepatotoxicity in mice.
Volume: 9
Issue: 3
Pages: e93013
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Publication
24298019 | J:316675
First Author: Wakabayashi N
Year: 2014
Journal: Mol Cell Biol
Title: Notch-Nrf2 axis: regulation of Nrf2 gene expression and cytoprotection by notch signaling.
Volume: 34
Issue: 4
Pages: 653-63
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Publication
23527105 | J:199381
First Author: Zhang YK
Year: 2013
Journal: PLoS One
Title: Genetic activation of Nrf2 protects against fasting-induced oxidative stress in livers of mice.
Volume: 8
Issue: 3
Pages: e59122
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Publication
21775727 | J:175825
First Author: Wu KC
Year: 2011
Journal: Toxicol Sci
Title: Beneficial role of Nrf2 in regulating NADPH generation and consumption.
Volume: 123
Issue: 2
Pages: 590-600
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Publication
25957295 | J:232447
First Author: Sussan TE
Year: 2015
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Nrf2 reduces allergic asthma in mice through enhanced airway epithelial cytoprotective function.
Volume: 309
Issue: 1
Pages: L27-36
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Publication
35561328 | J:327828
First Author: Satoh H
Year: 2022
Journal: Carcinogenesis
Title: Genomic landscape of chemical-induced lung tumors under Nrf2 different expression levels.
Volume: 43
Issue: 7
Pages: 613-623
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Publication
23590302 | J:221771
First Author: Eba S
Year: 2013
Journal: Am J Respir Cell Mol Biol
Title: The nuclear factor erythroid 2-related factor 2 activator oltipraz attenuates chronic hypoxia-induced cardiopulmonary alterations in mice.
Volume: 49
Issue: 2
Pages: 324-33
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Publication
28533375 | J:242279
First Author: Quinti L
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: KEAP1-modifying small molecule reveals muted NRF2 signaling responses in neural stem cells from Huntington's disease patients.
Volume: 114
Issue: 23
Pages: E4676-E4685
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Publication
24062466 | J:202311
First Author: Wei Y
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Nrf2 acts cell-autonomously in endothelium to regulate tip cell formation and vascular branching.
Volume: 110
Issue: 41
Pages: E3910-8
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Publication
31941842 | J:323060
 
First Author: Jobbagy S
Year: 2020
Journal: JCI Insight
Title: Nrf2 activation protects against lithium-induced nephrogenic diabetes insipidus.
Volume: 5
Issue: 1
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Publication
28512147 | J:259492
 
First Author: Nezu M
Year: 2017
Journal: Sci Signal
Title: Nrf2 inactivation enhances placental angiogenesis in a preeclampsia mouse model and improves maternal and fetal outcomes.
Volume: 10
Issue: 479
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Publication
20513672 | J:164704
First Author: Satoh H
Year: 2010
Journal: Carcinogenesis
Title: Nrf2-deficiency creates a responsive microenvironment for metastasis to the lung.
Volume: 31
Issue: 10
Pages: 1833-43
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Publication
33707458 | J:303403
First Author: Sakai E
Year: 2021
Journal: Sci Rep
Title: Liquid-phase ASEM imaging of cellular and structural details in cartilage and bone formed during endochondral ossification: Keap1-deficient osteomalacia.
Volume: 11
Issue: 1
Pages: 5722
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Publication
23921124 | J:201627
First Author: Singh A
Year: 2013
Journal: J Clin Invest
Title: Transcription factor NRF2 regulates miR-1 and miR-206 to drive tumorigenesis.
Volume: 123
Issue: 7
Pages: 2921-34
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Publication
19246623 | J:149163
First Author: Reisman SA
Year: 2009
Journal: Toxicol Sci
Title: Nrf2 activation enhances biliary excretion of sulfobromophthalein by inducing glutathione-S-transferase activity.
Volume: 109
Issue: 1
Pages: 24-30
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Publication
23017736 | J:188996
First Author: Zhang YK
Year: 2012
Journal: Toxicol Appl Pharmacol
Title: Nrf2 deficiency improves glucose tolerance in mice fed a high-fat diet.
Volume: 264
Issue: 3
Pages: 305-14
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Publication
38060331 | J:360347
 
First Author: Schaer DJ
Year: 2023
Journal: J Clin Invest
Title: Hemorrhage-activated NRF2 in tumor-associated macrophages drives cancer growth, invasion, and immunotherapy resistance.
Volume: 134
Issue: 3
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Publication
24953182 | J:310691
First Author: Paul MK
Year: 2014
Journal: Cell Stem Cell
Title: Dynamic changes in intracellular ROS levels regulate airway basal stem cell homeostasis through Nrf2-dependent Notch signaling.
Volume: 15
Issue: 2
Pages: 199-214
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Publication
32738332 | J:301176
 
First Author: Zhang Y
Year: 2020
Journal: Toxicol Appl Pharmacol
Title: Effects of ablation and activation of Nrf2 on bile acid homeostasis in male mice.
Volume: 403
Pages: 115170
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Publication
35618180 | J:325602
 
First Author: Panda H
Year: 2022
Journal: Free Radic Biol Med
Title: Halofuginone micelle nanoparticles eradicate Nrf2-activated lung adenocarcinoma without systemic toxicity.
Volume: 187
Pages: 92-104
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Publication
21882243 | J:176592
First Author: Granado N
Year: 2011
Journal: Glia
Title: Nrf2 deficiency potentiates methamphetamine-induced dopaminergic axonal damage and gliosis in the striatum.
Volume: 59
Issue: 12
Pages: 1850-63
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Publication
27020858 | J:231827
First Author: Satoh H
Year: 2016
Journal: Cancer Res
Title: NRF2 Intensifies Host Defense Systems to Prevent Lung Carcinogenesis, but After Tumor Initiation Accelerates Malignant Cell Growth.
Volume: 76
Issue: 10
Pages: 3088-96
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Publication
35192689 | J:324250
First Author: Baumel-Alterzon S
Year: 2022
Journal: Diabetes
Title: Nrf2 Regulates β-Cell Mass by Suppressing β-Cell Death and Promoting β-Cell Proliferation.
Volume: 71
Issue: 5
Pages: 989-1011
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Publication
23295186 | J:206545
 
First Author: Koriyama Y
Year: 2013
Journal: Brain Res
Title: Protective effect of lipoic acid against oxidative stress is mediated by Keap1/Nrf2-dependent heme oxygenase-1 induction in the RGC-5 cellline.
Volume: 1499
Pages: 145-57
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Publication
31155513 | J:289434
 
First Author: Shanmugam G
Year: 2019
Journal: Redox Biol
Title: Enhanced Keap1-Nrf2 signaling protects the myocardium from isoproterenol-induced pathological remodeling in mice.
Volume: 27
Pages: 101212
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Publication
32197464 | J:299828
 
First Author: Li L
Year: 2020
Journal: Molecules
Title: Protective Effect of Astaxanthin on Ochratoxin A-Induced Kidney Injury to Mice by Regulating Oxidative Stress-Related NRF2/KEAP1 Pathway.
Volume: 25
Issue: 6
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Publication
19901266 | J:156836
First Author: Motohashi H
Year: 2010
Journal: Blood
Title: NF-E2 domination over Nrf2 promotes ROS accumulation and megakaryocytic maturation.
Volume: 115
Issue: 3
Pages: 677-86
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Publication
31015205 | J:290442
First Author: Keleku-Lukwete N
Year: 2019
Journal: Blood Adv
Title: Nrf2 activation in myeloid cells and endothelial cells differentially mitigates sickle cell disease pathology in mice.
Volume: 3
Issue: 8
Pages: 1285-1297
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Publication
37857700 | J:346049
First Author: Ye X
Year: 2023
Journal: Commun Biol
Title: Sulforaphane decreases serum selenoprotein P levels through enhancement of lysosomal degradation independent of Nrf2.
Volume: 6
Issue: 1
Pages: 1060
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Publication
35921423 | J:343849
First Author: Vasavda C
Year: 2022
Journal: Sci Adv
Title: Identification of the NRF2 transcriptional network as a therapeutic target for trigeminal neuropathic pain.
Volume: 8
Issue: 31
Pages: eabo5633
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Publication
26621751 | J:228197
First Author: Wei Y
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Nrf2 in ischemic neurons promotes retinal vascular regeneration through regulation of semaphorin 6A.
Volume: 112
Issue: 50
Pages: E6927-36
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Publication
37686150 | J:341123
 
First Author: Wakabayashi N
Year: 2023
Journal: Int J Mol Sci
Title: Forced Hepatic Expression of NRF2 or NQO1 Impedes Hepatocyte Lipid Accumulation in a Lipodystrophy Mouse Model.
Volume: 24
Issue: 17
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Publication
32295843 | J:298951
First Author: Miller WP
Year: 2020
Journal: J Biol Chem
Title: The stress response protein REDD1 promotes diabetes-induced oxidative stress in the retina by Keap1-independent Nrf2 degradation.
Volume: 295
Issue: 21
Pages: 7350-7361
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Publication
18826952 | J:143468
First Author: Ohtsuji M
Year: 2008
Journal: J Biol Chem
Title: Nrf1 and Nrf2 play distinct roles in activation of antioxidant response element-dependent genes.
Volume: 283
Issue: 48
Pages: 33554-62
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Publication
28228267 | J:250943
First Author: Yagishita Y
Year: 2017
Journal: Cell Rep
Title: Nrf2 Improves Leptin and Insulin Resistance Provoked by Hypothalamic Oxidative Stress.
Volume: 18
Issue: 8
Pages: 2030-2044
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Publication
30463003 | J:270407
First Author: Baardman J
Year: 2018
Journal: Cell Rep
Title: A Defective Pentose Phosphate Pathway Reduces Inflammatory Macrophage Responses during Hypercholesterolemia.
Volume: 25
Issue: 8
Pages: 2044-2052.e5
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Publication
31107239 | J:277350
   
First Author: Kang YP
Year: 2019
Journal: Elife
Title: Cysteine dioxygenase 1 is a metabolic liability for non-small cell lung cancer.
Volume: 8
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Publication
36209041 | J:330585
 
First Author: Fragoulis A
Year: 2022
Journal: Redox Biol
Title: Nrf2 induces malignant transformation of hepatic progenitor cells by inducing β-catenin expression.
Volume: 57
Pages: 102453
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Publication
21490276 | J:170808
First Author: Harvey CJ
Year: 2011
Journal: Sci Transl Med
Title: Targeting Nrf2 signaling improves bacterial clearance by alveolar macrophages in patients with COPD and in a mouse model.
Volume: 3
Issue: 78
Pages: 78ra32
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Publication
35204252 | J:347229
 
First Author: Kim EY
Year: 2022
Journal: Antioxidants (Basel)
Title: NRF2 Activation in Autophagy Defects Suppresses a Pharmacological Transactivation of the Nuclear Receptor FXR.
Volume: 11
Issue: 2
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Publication
31932477 | J:291599
 
First Author: Uruno A
Year: 2020
Journal: Mol Cell Biol
Title: Nrf2 Suppresses Oxidative Stress and Inflammation in App Knock-In Alzheimer's Disease Model Mice.
Volume: 40
Issue: 6
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Publication
35203398 | J:321621
 
First Author: Kim EY
Year: 2022
Journal: Cells
Title: Basal Autophagy Is Necessary for A Pharmacologic PPARα Transactivation.
Volume: 11
Issue: 4
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Publication
22789539 | J:191016
First Author: Mitsuishi Y
Year: 2012
Journal: Cancer Cell
Title: Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming.
Volume: 22
Issue: 1
Pages: 66-79
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Publication
25777368 | J:230344
First Author: Goto M
Year: 2015
Journal: Genes Cells
Title: Alcohol dehydrogenase 3 contributes to the protection of liver from nonalcoholic steatohepatitis.
Volume: 20
Issue: 6
Pages: 464-80
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29515034 | J:271172
 
First Author: Chartoumpekis DV
Year: 2018
Journal: JCI Insight
Title: Nrf2 prevents Notch-induced insulin resistance and tumorigenesis in mice.
Volume: 3
Issue: 5
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16135796 | J:101374
First Author: Katsuoka F
Year: 2005
Journal: Mol Cell Biol
Title: Genetic evidence that small maf proteins are essential for the activation of antioxidant response element-dependent genes.
Volume: 25
Issue: 18
Pages: 8044-51
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Publication
21185264 | J:168468
First Author: Inoue D
Year: 2011
Journal: Biochem Biophys Res Commun
Title: Inducible disruption of autophagy in the lung causes airway hyper-responsiveness.
Volume: 405
Issue: 1
Pages: 13-8
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29240881 | J:246048
First Author: Hamada S
Year: 2017
Journal: Carcinogenesis
Title: Nrf2 promotes mutant K-ras/p53-driven pancreatic carcinogenesis.
Volume: 38
Issue: 6
Pages: 661-670
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Publication
36963288 | J:346347
 
First Author: Xu T
Year: 2023
Journal: Redox Biol
Title: Git1-PGK1 interaction achieves self-protection against spinal cord ischemia-reperfusion injury by modulating Keap1/Nrf2 signaling.
Volume: 62
Pages: 102682
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Publication
22222206 | J:181228
First Author: Kwon J
Year: 2012
Journal: EMBO Rep
Title: Assurance of mitochondrial integrity and mammalian longevity by the p62-Keap1-Nrf2-Nqo1 cascade.
Volume: 13
Issue: 2
Pages: 150-6
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Publication
20173742 | J:172945
First Author: Komatsu M
Year: 2010
Journal: Nat Cell Biol
Title: The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1.
Volume: 12
Issue: 3
Pages: 213-23
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Publication
22586274 | J:186656
First Author: Hirotsu Y
Year: 2012
Journal: Mol Cell Biol
Title: NF-E2-related factor 1 (Nrf1) serves as a novel regulator of hepatic lipid metabolism through regulation of the Lipin1 and PGC-1β genes.
Volume: 32
Issue: 14
Pages: 2760-70
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Publication
35031770 | J:327150
First Author: Vallelian F
Year: 2022
Journal: Cell Death Differ
Title: Heme-stress activated NRF2 skews fate trajectories of bone marrow cells from dendritic cells towards red pulp-like macrophages in hemolytic anemia.
Volume: 29
Issue: 8
Pages: 1450-1465
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17591699 | J:125008
First Author: Cho MK
Year: 2007
Journal: Mol Cell Biol
Title: Role of Galpha12 and Galpha13 as novel switches for the activity of Nrf2, a key antioxidative transcription factor.
Volume: 27
Issue: 17
Pages: 6195-208
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Publication
37597423 | J:339677
 
First Author: Baird L
Year: 2023
Journal: Redox Biol
Title: A NRF2-induced secretory phenotype activates immune surveillance to remove irreparably damaged cells.
Volume: 66
Pages: 102845
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Publication
25049227 | J:216807
First Author: Kageyama S
Year: 2014
Journal: J Biol Chem
Title: Proteasome dysfunction activates autophagy and the Keap1-Nrf2 pathway.
Volume: 289
Issue: 36
Pages: 24944-55
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Publication
17709388 | J:126776
First Author: Shin S
Year: 2007
Journal: Mol Cell Biol
Title: NRF2 modulates aryl hydrocarbon receptor signaling: influence on adipogenesis.
Volume: 27
Issue: 20
Pages: 7188-97
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Publication
24859727 | J:302767
 
First Author: Walsh J
Year: 2014
Journal: J Proteomics
Title: Identification and quantification of the basal and inducible Nrf2-dependent proteomes in mouse liver: biochemical, pharmacological and toxicological implications.
Volume: 108
Pages: 171-87
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Publication
21245377 | J:170616
First Author: Rada P
Year: 2011
Journal: Mol Cell Biol
Title: SCF/{beta}-TrCP promotes glycogen synthase kinase 3-dependent degradation of the Nrf2 transcription factor in a Keap1-independent manner.
Volume: 31
Issue: 6
Pages: 1121-33
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Publication
31242413 | J:294372
First Author: Brandsma I
Year: 2019
Journal: Cell Rep
Title: HSF2BP Interacts with a Conserved Domain of BRCA2 and Is Required for Mouse Spermatogenesis.
Volume: 27
Issue: 13
Pages: 3790-3798.e7
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Publication
35425962 | J:324033
First Author: Yousefi M
Year: 2022
Journal: Cancer Res
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