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Search results 101 to 200 out of 801 for Lgr5

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Category: Publication
Type Details Score
Publication
First Author: Zhang S
Year: 2019
Journal: Nat Commun
Title: Both fallopian tube and ovarian surface epithelium are cells-of-origin for high-grade serous ovarian carcinoma.
Volume: 10
Issue: 1
Pages: 5367
Publication
First Author: Snippert HJ
Year: 2010
Journal: Science
Title: Lgr6 marks stem cells in the hair follicle that generate all cell lineages of the skin.
Volume: 327
Issue: 5971
Pages: 1385-9
Publication
First Author: Myant KB
Year: 2013
Journal: Cell Stem Cell
Title: ROS production and NF-κB activation triggered by RAC1 facilitate WNT-driven intestinal stem cell proliferation and colorectal cancer initiation.
Volume: 12
Issue: 6
Pages: 761-73
Publication
First Author: Itzkovitz S
Year: 2011
Journal: Nat Cell Biol
Title: Single-molecule transcript counting of stem-cell markers in the mouse intestine.
Volume: 14
Issue: 1
Pages: 106-14
Publication
First Author: Lehoczky JA
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Lgr6 marks nail stem cells and is required for digit tip regeneration.
Volume: 112
Issue: 43
Pages: 13249-54
Publication
First Author: Won JH
Year: 2022
Journal: Nat Commun
Title: CCN1 interacts with integrins to regulate intestinal stem cell proliferation and differentiation.
Volume: 13
Issue: 1
Pages: 3117
Publication
First Author: Tian H
Year: 2011
Journal: Nature
Title: A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable.
Volume: 478
Issue: 7368
Pages: 255-9
Publication
First Author: Barker N
Year: 2012
Journal: Cell Rep
Title: Lgr5(+ve) stem/progenitor cells contribute to nephron formation during kidney development.
Volume: 2
Issue: 3
Pages: 540-52
Publication
First Author: Schepers AG
Year: 2012
Journal: Science
Title: Lineage tracing reveals Lgr5+ stem cell activity in mouse intestinal adenomas.
Volume: 337
Issue: 6095
Pages: 730-5
Publication
First Author: Leushacke M
Year: 2017
Journal: Nat Cell Biol
Title: Lgr5-expressing chief cells drive epithelial regeneration and cancer in the oxyntic stomach.
Volume: 19
Issue: 7
Pages: 774-786
Publication
First Author: Yan KS
Year: 2017
Journal: Cell Stem Cell
Title: Intestinal Enteroendocrine Lineage Cells Possess Homeostatic and Injury-Inducible Stem Cell Activity.
Volume: 21
Issue: 1
Pages: 78-90.e6
Publication  
First Author: Gu NX
Year: 2023
Journal: Development
Title: Frizzled 7 modulates goblet and Paneth cell fate, and maintains homeostasis in mouse intestine.
Volume: 150
Issue: 4
Publication
First Author: Lourenço FC
Year: 2014
Journal: Gut
Title: Reduced LIMK2 expression in colorectal cancer reflects its role in limiting stem cell proliferation.
Volume: 63
Issue: 3
Pages: 480-93
Publication
First Author: Lee YS
Year: 2018
Journal: Cell Host Microbe
Title: Microbiota-Derived Lactate Accelerates Intestinal Stem-Cell-Mediated Epithelial Development.
Volume: 24
Issue: 6
Pages: 833-846.e6
Publication
First Author: Sheng X
Year: 2020
Journal: Cell Rep
Title: Cycling Stem Cells Are Radioresistant and Regenerate the Intestine.
Volume: 32
Issue: 4
Pages: 107952
Publication
First Author: Lei NY
Year: 2014
Journal: PLoS One
Title: Intestinal subepithelial myofibroblasts support the growth of intestinal epithelial stem cells.
Volume: 9
Issue: 1
Pages: e84651
Publication
First Author: Davidson LA
Year: 2012
Journal: Biochim Biophys Acta
Title: Alteration of colonic stem cell gene signatures during the regenerative response to injury.
Volume: 1822
Issue: 10
Pages: 1600-7
Publication
First Author: Yuan S
Year: 2021
Journal: Oncogene
Title: miR-22 promotes stem cell traits via activating Wnt/β-catenin signaling in cutaneous squamous cell carcinoma.
Volume: 40
Issue: 39
Pages: 5799-5813
Publication
First Author: Hoeck JD
Year: 2017
Journal: Nat Cell Biol
Title: Stem cell plasticity enables hair regeneration following Lgr5+ cell loss.
Volume: 19
Issue: 6
Pages: 666-676
Publication
First Author: Walther N
Year: 2024
Journal: Cell Rep
Title: Automated live-cell single-molecule tracking in enteroid monolayers reveals transcription factor dynamics probing lineage-determining function.
Volume: 43
Issue: 11
Pages: 114914
Publication
First Author: Trentesaux C
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Essential role for autophagy protein ATG7 in the maintenance of intestinal stem cell integrity.
Volume: 117
Issue: 20
Pages: 11136-11146
Publication      
First Author: DeStefano Shields CE
Year: 2021
Journal: Cancer Discov
Title: Bacterial-Driven Inflammation and Mutant BRAF Expression Combine to Promote Murine Colon Tumorigenesis That Is Sensitive to Immune Checkpoint Therapy.
Publication
First Author: Kabiri Z
Year: 2014
Journal: Development
Title: Stroma provides an intestinal stem cell niche in the absence of epithelial Wnts.
Volume: 141
Issue: 11
Pages: 2206-15
Publication
First Author: Liu Z
Year: 2019
Journal: Exp Cell Res
Title: PERK is essential for proliferation of intestinal stem cells in mice.
Volume: 375
Issue: 1
Pages: 42-51
Publication
First Author: Kadur Lakshminarasimha Murthy P
Year: 2022
Journal: Dev Cell
Title: Epigenetic basis of oncogenic-Kras-mediated epithelial-cellular proliferation and plasticity.
Volume: 57
Issue: 3
Pages: 310-328.e9
Publication
First Author: Jeffery V
Year: 2017
Journal: J Immunol
Title: IL-6 Signaling Regulates Small Intestinal Crypt Homeostasis.
Volume: 199
Issue: 1
Pages: 304-311
Publication
First Author: Ghanem LR
Year: 2014
Journal: Gene Expr Patterns
Title: Specific enrichment of the RNA-binding proteins PCBP1 and PCBP2 in chief cells of the murine gastric mucosa.
Volume: 14
Issue: 2
Pages: 78-87
Publication
First Author: Cerretelli G
Year: 2021
Journal: J Pathol
Title: Ethanol-induced formation of colorectal tumours and precursors in a mouse model of Lynch syndrome.
Volume: 255
Issue: 4
Pages: 464-474
Publication  
First Author: Liu J
Year: 2024
Journal: Redox Biol
Title: ATF3-CBS signaling axis coordinates ferroptosis and tumorigenesis in colorectal cancer.
Volume: 71
Pages: 103118
Publication
First Author: Hou Q
Year: 2022
Journal: Cell Rep
Title: Bacillus subtilis programs the differentiation of intestinal secretory lineages to inhibit Salmonella infection.
Volume: 40
Issue: 13
Pages: 111416
Publication
First Author: Rispal J
Year: 2019
Journal: Nat Commun
Title: The H2A.Z histone variant integrates Wnt signaling in intestinal epithelial homeostasis.
Volume: 10
Issue: 1
Pages: 1827
Publication
First Author: Cheasley D
Year: 2011
Journal: Stem Cells
Title: Myb controls intestinal stem cell genes and self-renewal.
Volume: 29
Issue: 12
Pages: 2042-50
Publication
First Author: Chai R
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Wnt signaling induces proliferation of sensory precursors in the postnatal mouse cochlea.
Volume: 109
Issue: 21
Pages: 8167-72
Publication  
First Author: Liu R
Year: 2019
Journal: Life Sci Alliance
Title: Constitutive STAT5 activation regulates Paneth and Paneth-like cells to control Clostridium difficile colitis.
Volume: 2
Issue: 2
Publication
First Author: Fumagalli A
Year: 2020
Journal: Cell Stem Cell
Title: Plasticity of Lgr5-Negative Cancer Cells Drives Metastasis in Colorectal Cancer.
Volume: 26
Issue: 4
Pages: 569-578.e7
Publication
First Author: Du J
Year: 2022
Journal: Dev Cell
Title: N(6)-adenomethylation of GsdmC is essential for Lgr5(+) stem cell survival to maintain normal colonic epithelial morphogenesis.
Volume: 57
Issue: 16
Pages: 1976-1994.e8
Publication
First Author: Lindemans CA
Year: 2015
Journal: Nature
Title: Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration.
Volume: 528
Issue: 7583
Pages: 560-564
Publication
First Author: Yang L
Year: 2024
Journal: Nat Commun
Title: NAD(+) dependent UPR(mt) activation underlies intestinal aging caused by mitochondrial DNA mutations.
Volume: 15
Issue: 1
Pages: 546
Publication  
First Author: Wang X
Year: 2015
Journal: Sci Rep
Title: Pharmacologically blocking p53-dependent apoptosis protects intestinal stem cells and mice from radiation.
Volume: 5
Pages: 8566
Publication
First Author: Pu C
Year: 2024
Journal: Adv Sci (Weinh)
Title: Low-Dose Chemotherapy Preferentially Shapes the Ileal Microbiome and Augments the Response to Immune Checkpoint Blockade by Activating AIM2 Inflammasome in Ileal Epithelial Cells.
Volume: 11
Issue: 11
Pages: e2304781
Publication
First Author: Minamide K
Year: 2020
Journal: Sci Rep
Title: IRF2 maintains the stemness of colonic stem cells by limiting physiological stress from interferon.
Volume: 10
Issue: 1
Pages: 14639
Publication
First Author: Stamp C
Year: 2021
Journal: Aging Cell
Title: Age-associated mitochondrial complex I deficiency is linked to increased stem cell proliferation rates in the mouse colon.
Volume: 20
Issue: 3
Pages: e13321
Publication
First Author: Ruscitto A
Year: 2023
Journal: Cell Stem Cell
Title: Lgr5-expressing secretory cells form a Wnt inhibitory niche in cartilage critical for chondrocyte identity.
Volume: 30
Issue: 9
Pages: 1179-1198.e7
Publication
First Author: Grün D
Year: 2016
Journal: Cell Stem Cell
Title: De Novo Prediction of Stem Cell Identity using Single-Cell Transcriptome Data.
Volume: 19
Issue: 2
Pages: 266-277
Publication
First Author: Nalapareddy K
Year: 2017
Journal: Cell Rep
Title: Canonical Wnt Signaling Ameliorates Aging of Intestinal Stem Cells.
Volume: 18
Issue: 11
Pages: 2608-2621
Publication
First Author: Choi J
Year: 2018
Journal: Sci Rep
Title: Intestinal crypts recover rapidly from focal damage with coordinated motion of stem cells that is impaired by aging.
Volume: 8
Issue: 1
Pages: 10989
Publication
First Author: Wiener Z
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Oncogenic mutations in intestinal adenomas regulate Bim-mediated apoptosis induced by TGF-β.
Volume: 111
Issue: 21
Pages: E2229-36
Publication
First Author: Syu LJ
Year: 2016
Journal: Oncotarget
Title: Invasive mouse gastric adenocarcinomas arising from Lgr5+ stem cells are dependent on crosstalk between the Hedgehog/GLI2 and mTOR pathways.
Volume: 7
Issue: 9
Pages: 10255-70
Publication
First Author: Sei Y
Year: 2011
Journal: Am J Physiol Gastrointest Liver Physiol
Title: A stem cell marker-expressing subset of enteroendocrine cells resides at the crypt base in the small intestine.
Volume: 300
Issue: 2
Pages: G345-56
Publication
First Author: Peck BC
Year: 2017
Journal: J Biol Chem
Title: Functional Transcriptomics in Diverse Intestinal Epithelial Cell Types Reveals Robust MicroRNA Sensitivity in Intestinal Stem Cells to Microbial Status.
Volume: 292
Issue: 7
Pages: 2586-2600
Publication
First Author: Rothenberg ME
Year: 2012
Journal: Gastroenterology
Title: Identification of a cKit(+) colonic crypt base secretory cell that supports Lgr5(+) stem cells in mice.
Volume: 142
Issue: 5
Pages: 1195-1205.e6
Publication
First Author: Szenker-Ravi E
Year: 2018
Journal: Nature
Title: RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6.
Volume: 557
Issue: 7706
Pages: 564-569
Publication
First Author: Huch M
Year: 2013
Journal: Nature
Title: In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration.
Volume: 494
Issue: 7436
Pages: 247-50
Publication    
First Author: Tao Y
Year: 2019
Journal: Elife
Title: Tailored tetravalent antibodies potently and specifically activate Wnt/Frizzled pathways in cells, organoids and mice.
Volume: 8
Publication
First Author: Rastetter RH
Year: 2014
Journal: Dev Biol
Title: Marker genes identify three somatic cell types in the fetal mouse ovary.
Volume: 394
Issue: 2
Pages: 242-52
Publication  
First Author: Olbertová K
Year: 2022
Journal: Front Cell Dev Biol
Title: Role of LGR5-positive mesenchymal cells in craniofacial development.
Volume: 10
Pages: 810527
Publication
First Author: Funk MC
Year: 2023
Journal: Dev Cell
Title: Aged intestinal stem cells propagate cell-intrinsic sources of inflammaging in mice.
Volume: 58
Issue: 24
Pages: 2914-2929.e7
Publication
First Author: Zheng Y
Year: 2018
Journal: Am J Physiol Endocrinol Metab
Title: Intestinal epithelial cell-specific IGF1 promotes the expansion of intestinal stem cells during epithelial regeneration and functions on the intestinal immune homeostasis.
Volume: 315
Issue: 4
Pages: E638-E649
Publication
First Author: Petropoulos M
Year: 2023
Journal: J Pathol
Title: Cdt1 overexpression drives colorectal carcinogenesis through origin overlicensing and DNA damage.
Volume: 259
Issue: 1
Pages: 10-20
Publication
First Author: Klaas M
Year: 2020
Journal: FEBS Lett
Title: Endogenous beta-galactosidase activity marks a TREM2-expressing Kupffer cell population in injured livers of Lgr5-LacZ and wild-type mice.
Volume: 594
Issue: 5
Pages: 958-970
Publication
First Author: Afrazi A
Year: 2014
Journal: J Biol Chem
Title: Toll-like receptor 4-mediated endoplasmic reticulum stress in intestinal crypts induces necrotizing enterocolitis.
Volume: 289
Issue: 14
Pages: 9584-99
Publication
First Author: Feng Y
Year: 2013
Journal: Am J Pathol
Title: Sox9 induction, ectopic Paneth cells, and mitotic spindle axis defects in mouse colon adenomatous epithelium arising from conditional biallelic Apc inactivation.
Volume: 183
Issue: 2
Pages: 493-503
Publication
First Author: Gross S
Year: 2015
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Nkx2.2 is expressed in a subset of enteroendocrine cells with expanded lineage potential.
Volume: 309
Issue: 12
Pages: G975-87
Publication
First Author: Stzepourginski I
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: CD34+ mesenchymal cells are a major component of the intestinal stem cells niche at homeostasis and after injury.
Volume: 114
Issue: 4
Pages: E506-E513
Publication
First Author: Yang L
Year: 2021
Journal: Nat Commun
Title: CREPT is required for murine stem cell maintenance during intestinal regeneration.
Volume: 12
Issue: 1
Pages: 270
Publication
First Author: Norona J
Year: 2020
Journal: Blood
Title: Glucagon-like peptide 2 for intestinal stem cell and Paneth cell repair during graft-versus-host disease in mice and humans.
Volume: 136
Issue: 12
Pages: 1442-1455
Publication
First Author: Zhao D
Year: 2018
Journal: J Clin Invest
Title: Survival signal REG3α prevents crypt apoptosis to control acute gastrointestinal graft-versus-host disease.
Volume: 128
Issue: 11
Pages: 4970-4979
Publication
First Author: Boonekamp KE
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Long-term expansion and differentiation of adult murine epidermal stem cells in 3D organoid cultures.
Volume: 116
Issue: 29
Pages: 14630-14638
Publication
First Author: Sorrentino G
Year: 2020
Journal: Gastroenterology
Title: Bile Acids Signal via TGR5 to Activate Intestinal Stem Cells and Epithelial Regeneration.
Volume: 159
Issue: 3
Pages: 956-968.e8
Publication
First Author: Li M
Year: 2015
Journal: Int J Biol Sci
Title: Krüppel-Like Factor 5 Promotes Epithelial Proliferation and DNA Damage Repair in the Intestine of Irradiated Mice.
Volume: 11
Issue: 12
Pages: 1458-68
Publication
First Author: Celià-Terrassa T
Year: 2017
Journal: Nat Cell Biol
Title: Normal and cancerous mammary stem cells evade interferon-induced constraint through the miR-199a-LCOR axis.
Volume: 19
Issue: 6
Pages: 711-723
Publication  
First Author: Huang K
Year: 2018
Journal: Biol Open
Title: JAK signaling regulates germline cyst breakdown and primordial follicle formation in mice.
Volume: 7
Issue: 1
Publication
First Author: Quigley DA
Year: 2009
Journal: Nature
Title: Genetic architecture of mouse skin inflammation and tumour susceptibility.
Volume: 458
Issue: 7237
Pages: 505-8
Publication
First Author: Hua G
Year: 2017
Journal: Cancer Res
Title: Distinct Levels of Radioresistance in Lgr5+ Colonic Epithelial Stem Cells versus Lgr5+ Small Intestinal Stem Cells.
Volume: 77
Issue: 8
Pages: 2124-2133
Publication
First Author: Planas-Paz L
Year: 2019
Journal: Cell Stem Cell
Title: YAP, but Not RSPO-LGR4/5, Signaling in Biliary Epithelial Cells Promotes a Ductular Reaction in Response to Liver Injury.
Volume: 25
Issue: 1
Pages: 39-53.e10
Publication  
First Author: Sayols S
Year: 2020
Journal: Development
Title: Signalling codes for the maintenance and lineage commitment of embryonic gastric epithelial progenitors.
Volume: 147
Issue: 18
Publication
First Author: Chen M
Year: 2015
Journal: Aging Cell
Title: Lgr5⁺ amacrine cells possess regenerative potential in the retina of adult mice.
Volume: 14
Issue: 4
Pages: 635-43
Publication
First Author: Bahar Halpern K
Year: 2020
Journal: Nat Commun
Title: Lgr5+ telocytes are a signaling source at the intestinal villus tip.
Volume: 11
Issue: 1
Pages: 1936
Publication
First Author: Wei W
Year: 2024
Journal: Cell Metab
Title: Psychological stress-induced microbial metabolite indole-3-acetate disrupts intestinal cell lineage commitment.
Volume: 36
Issue: 3
Pages: 466-483.e7
Publication
First Author: Sun Q
Year: 2024
Journal: Cell Prolif
Title: AAV-mediated Gpm6b expression supports hair cell reprogramming.
Volume: 57
Issue: 7
Pages: e13620
Publication
First Author: Thorne CA
Year: 2018
Journal: Dev Cell
Title: Enteroid Monolayers Reveal an Autonomous WNT and BMP Circuit Controlling Intestinal Epithelial Growth and Organization.
Volume: 44
Issue: 5
Pages: 624-633.e4
Publication
First Author: Cao YG
Year: 2022
Journal: Cell Host Microbe
Title: Faecalibaculum rodentium remodels retinoic acid signaling to govern eosinophil-dependent intestinal epithelial homeostasis.
Volume: 30
Issue: 9
Pages: 1295-1310.e8
Publication
First Author: Oda Y
Year: 2021
Journal: Sci Adv
Title: Discovery of anti-inflammatory physiological peptides that promote tissue repair by reinforcing epithelial barrier formation.
Volume: 7
Issue: 47
Pages: eabj6895
Publication    
First Author: Wang L
Year: 2018
Journal: Elife
Title: miR-34a is a microRNA safeguard for Citrobacter-induced inflammatory colon oncogenesis.
Volume: 7
Publication  
First Author: Lin J
Year: 2015
Journal: Front Cell Neurosci
Title: Hair cell damage recruited Lgr5-expressing cells are hair cell progenitors in neonatal mouse utricle.
Volume: 9
Pages: 113
Publication
First Author: Fazilaty H
Year: 2021
Journal: Cell Rep
Title: Tracing colonic embryonic transcriptional profiles and their reactivation upon intestinal damage.
Volume: 36
Issue: 5
Pages: 109484
Publication  
First Author: Ramadan R
Year: 2022
Journal: Biol Open
Title: The extracellular matrix controls stem cell specification and crypt morphology in the developing and adult mouse gut.
Volume: 11
Issue: 12
Publication  
First Author: Mackie GM
Year: 2021
Journal: JCI Insight
Title: Bacterial cancer therapy in autochthonous colorectal cancer affects tumor growth and metabolic landscape.
Volume: 6
Issue: 23
Publication
First Author: Shiokawa D
Year: 2017
Journal: Cell Rep
Title: The Induction of Selected Wnt Target Genes by Tcf1 Mediates Generation of Tumorigenic Colon Stem Cells.
Volume: 19
Issue: 5
Pages: 981-994
Publication
First Author: Tao S
Year: 2015
Journal: EMBO J
Title: Wnt activity and basal niche position sensitize intestinal stem and progenitor cells to DNA damage.
Volume: 34
Issue: 5
Pages: 624-40
Publication
First Author: Wojciechowicz K
Year: 2014
Journal: Gastroenterology
Title: Temozolomide increases the number of mismatch repair-deficient intestinal crypts and accelerates tumorigenesis in a mouse model of Lynch syndrome.
Volume: 147
Issue: 5
Pages: 1064-72.e5
Publication
First Author: Yan KS
Year: 2017
Journal: Nature
Title: Non-equivalence of Wnt and R-spondin ligands during Lgr5+ intestinal stem-cell self-renewal.
Volume: 545
Issue: 7653
Pages: 238-242
Publication
First Author: Young MA
Year: 2018
Journal: Stem Cells
Title: Subtle Deregulation of the Wnt-Signaling Pathway Through Loss of Apc2 Reduces the Fitness of Intestinal Stem Cells.
Volume: 36
Issue: 1
Pages: 114-122
Publication
First Author: Callejas-Valera JL
Year: 2016
Journal: Carcinogenesis
Title: mTOR inhibition prevents rapid-onset of carcinogen-induced malignancies in a novel inducible HPV-16 E6/E7 mouse model.
Volume: 37
Issue: 10
Pages: 1014-25
Publication  
First Author: Saha S
Year: 2016
Journal: Nat Commun
Title: Macrophage-derived extracellular vesicle-packaged WNTs rescue intestinal stem cells and enhance survival after radiation injury.
Volume: 7
Pages: 13096
Publication  
First Author: Shechtman LA
Year: 2023
Journal: Development
Title: High Sox2 expression predicts taste lineage competency of lingual progenitors in vitro.
Volume: 150
Issue: 4
Publication
First Author: Riehl TE
Year: 2020
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Hyaluronic acid promotes Lgr5+ stem cell proliferation and crypt fission through TLR4 and PGE2 transactivation of EGFR.
Volume: 319
Issue: 1
Pages: G63-G73
Publication
First Author: Jang BG
Year: 2013
Journal: PLoS One
Title: Distribution of LGR5+ cells and associated implications during the early stage of gastric tumorigenesis.
Volume: 8
Issue: 12
Pages: e82390
Publication
First Author: Lin W
Year: 2019
Journal: FASEB J
Title: Lgr5-overexpressing mesenchymal stem cells augment fracture healing through regulation of Wnt/ERK signaling pathways and mitochondrial dynamics.
Volume: 33
Issue: 7
Pages: 8565-8577
Publication
First Author: Yum MK
Year: 2016
Journal: Cancer Res
Title: AIMP2 Controls Intestinal Stem Cell Compartments and Tumorigenesis by Modulating Wnt/β-Catenin Signaling.
Volume: 76
Issue: 15
Pages: 4559-68