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Search results 101 to 200 out of 380 for Lmna

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Category: Publication
Type Details Score
Publication
First Author: Fong LG
Year: 2006
Journal: J Clin Invest
Title: Prelamin A and lamin A appear to be dispensable in the nuclear lamina.
Volume: 116
Issue: 3
Pages: 743-52
Publication  
First Author: Wang Y
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: Abolishing the prelamin A ZMPSTE24 cleavage site leads to progeroid phenotypes with near-normal longevity in mice.
Volume: 119
Issue: 9
Publication
First Author: Wada E
Year: 2019
Journal: PLoS One
Title: Deficiency of emerin contributes differently to the pathogenesis of skeletal and cardiac muscles in LmnaH222P/H222P mutant mice.
Volume: 14
Issue: 8
Pages: e0221512
Publication
First Author: Wang Y
Year: 2022
Journal: Nat Commun
Title: Lamin A/C-dependent chromatin architecture safeguards naïve pluripotency to prevent aberrant cardiovascular cell fate and function.
Volume: 13
Issue: 1
Pages: 6663
Publication
First Author: Varela I
Year: 2005
Journal: Nature
Title: Accelerated ageing in mice deficient in Zmpste24 protease is linked to p53 signalling activation.
Volume: 437
Issue: 7058
Pages: 564-8
Publication
First Author: Jung HJ
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Regulation of prelamin A but not lamin C by miR-9, a brain-specific microRNA.
Volume: 109
Issue: 7
Pages: E423-31
Publication
First Author: Ho CY
Year: 2013
Journal: Nature
Title: Lamin A/C and emerin regulate MKL1-SRF activity by modulating actin dynamics.
Volume: 497
Issue: 7450
Pages: 507-11
Publication
First Author: Nikolova V
Year: 2004
Journal: J Clin Invest
Title: Defects in nuclear structure and function promote dilated cardiomyopathy in lamin A/C-deficient mice.
Volume: 113
Issue: 3
Pages: 357-69
Publication
First Author: Wu W
Year: 2014
Journal: Hum Mol Genet
Title: Depletion of extracellular signal-regulated kinase 1 in mice with cardiomyopathy caused by lamin A/C gene mutation partially prevents pathology before isoenzyme activation.
Volume: 23
Issue: 1
Pages: 1-11
Publication
First Author: Melcon G
Year: 2006
Journal: Hum Mol Genet
Title: Loss of emerin at the nuclear envelope disrupts the Rb1/E2F and MyoD pathways during muscle regeneration.
Volume: 15
Issue: 4
Pages: 637-51
Publication
First Author: Auguste G
Year: 2018
Journal: Circ Res
Title: Suppression of Activated FOXO Transcription Factors in the Heart Prolongs Survival in a Mouse Model of Laminopathies.
Volume: 122
Issue: 5
Pages: 678-692
Publication
First Author: Muchir A
Year: 2014
Journal: Biochem Biophys Res Commun
Title: Mitogen-activated protein kinase kinase 1/2 inhibition and angiotensin II converting inhibition in mice with cardiomyopathy caused by lamin A/C gene mutation.
Volume: 452
Issue: 4
Pages: 958-61
Publication
First Author: Zhang H
Year: 2013
Journal: Aging Cell
Title: Mouse models of laminopathies.
Volume: 12
Issue: 1
Pages: 2-10
Publication
First Author: Bertrand AT
Year: 2012
Journal: Hum Mol Genet
Title: DelK32-lamin A/C has abnormal location and induces incomplete tissue maturation and severe metabolic defects leading to premature death.
Volume: 21
Issue: 5
Pages: 1037-48
Publication
First Author: Huang ZP
Year: 2015
Journal: J Clin Invest
Title: Cardiomyocyte-enriched protein CIP protects against pathophysiological stresses and regulates cardiac homeostasis.
Volume: 125
Issue: 11
Pages: 4122-34
Publication
First Author: Nakajima N
Year: 1995
Journal: FEBS Lett
Title: Genomic structure of the mouse A-type lamin gene locus encoding somatic and germ cell-specific lamins.
Volume: 365
Issue: 2-3
Pages: 108-14
Publication
First Author: Furukawa K
Year: 1994
Journal: Exp Cell Res
Title: Identification and cloning of an mRNA coding for a germ cell-specific A-type lamin in mice.
Volume: 212
Issue: 2
Pages: 426-30
Publication
First Author: Nakajima N
Year: 1993
Journal: Biochim Biophys Acta
Title: Nucleotide sequence of a mouse lamin A cDNA and its deduced amino acid sequence.
Volume: 1171
Issue: 3
Pages: 311-4
Publication
First Author: Sullivan T
Year: 1999
Journal: J Cell Biol
Title: Loss of A-type lamin expression compromises nuclear envelope integrity leading to muscular dystrophy.
Volume: 147
Issue: 5
Pages: 913-20
Publication
First Author: Zhang YQ
Year: 2008
Journal: J Cell Biol
Title: Sumoylation regulates lamin A function and is lost in lamin A mutants associated with familial cardiomyopathies.
Volume: 182
Issue: 1
Pages: 35-9
Publication
First Author: Tong J
Year: 2011
Journal: Mech Ageing Dev
Title: Lamin A/C deficiency is associated with fat infiltration of muscle and bone.
Volume: 132
Issue: 11-12
Pages: 552-9
Publication
First Author: Li W
Year: 2011
Journal: PLoS One
Title: Decreased bone formation and osteopenia in lamin a/c-deficient mice.
Volume: 6
Issue: 4
Pages: e19313
Publication
First Author: Sun S
Year: 2020
Journal: Sci Adv
Title: Vascular endothelium-targeted Sirt7 gene therapy rejuvenates blood vessels and extends life span in a Hutchinson-Gilford progeria model.
Volume: 6
Issue: 8
Pages: eaay5556
Publication
First Author: Ghosh S
Year: 2019
Journal: Cell Rep
Title: Deformation Microscopy for Dynamic Intracellular and Intranuclear Mapping of Mechanics with High Spatiotemporal Resolution.
Volume: 27
Issue: 5
Pages: 1607-1620.e4
Publication
First Author: Frock RL
Year: 2012
Journal: PLoS One
Title: Cardiomyocyte-specific expression of lamin a improves cardiac function in Lmna-/- mice.
Volume: 7
Issue: 8
Pages: e42918
Publication
First Author: Mehl JL
Year: 2022
Journal: iScience
Title: Blockage of lamin-A/C loss diminishes the pro-inflammatory macrophage response.
Volume: 25
Issue: 12
Pages: 105528
Publication
First Author: Cesarini E
Year: 2015
Journal: J Cell Biol
Title: Lamin A/C sustains PcG protein architecture, maintaining transcriptional repression at target genes.
Volume: 211
Issue: 3
Pages: 533-51
Publication
First Author: González-Granado JM
Year: 2014
Journal: Sci Signal
Title: Nuclear envelope lamin-A couples actin dynamics with immunological synapse architecture and T cell activation.
Volume: 7
Issue: 322
Pages: ra37
Publication
First Author: Tamiello C
Year: 2017
Journal: J Cell Sci
Title: Cellular strain avoidance is mediated by a functional actin cap - observations in an Lmna-deficient cell model.
Volume: 130
Issue: 4
Pages: 779-790
Publication
First Author: Ramos FJ
Year: 2012
Journal: Sci Transl Med
Title: Rapamycin reverses elevated mTORC1 signaling in lamin A/C-deficient mice, rescues cardiac and skeletal muscle function, and extends survival.
Volume: 4
Issue: 144
Pages: 144ra103
Publication
First Author: Khatau SB
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: A perinuclear actin cap regulates nuclear shape.
Volume: 106
Issue: 45
Pages: 19017-22
Publication
First Author: Fan JR
Year: 2020
Journal: EMBO Rep
Title: Lamin A-mediated nuclear lamina integrity is required for proper ciliogenesis.
Volume: 21
Issue: 10
Pages: e49680
Publication
First Author: Alsheimer M
Year: 2004
Journal: J Cell Sci
Title: Disruption of spermatogenesis in mice lacking A-type lamins.
Volume: 117
Issue: Pt 7
Pages: 1173-8
Publication
First Author: Villa-Bellosta R
Year: 2013
Journal: Circulation
Title: Defective extracellular pyrophosphate metabolism promotes vascular calcification in a mouse model of Hutchinson-Gilford progeria syndrome that is ameliorated on pyrophosphate treatment.
Volume: 127
Issue: 24
Pages: 2442-51
Publication
First Author: Grover J
Year: 2007
Journal: Matrix Biol
Title: The consequence of PRELP overexpression on skin.
Volume: 26
Issue: 2
Pages: 140-3
Publication
First Author: Thomasson R
Year: 2019
Journal: Hum Mol Genet
Title: Alteration of performance in a mouse model of Emery-Dreifuss muscular dystrophy caused by A-type lamins gene mutation.
Volume: 28
Issue: 13
Pages: 2237-2244
Publication  
First Author: Vignier N
Year: 2019
Journal: Biochem Biophys Rep
Title: Effect of genetic background on the cardiac phenotype in a mouse model of Emery-Dreifuss muscular dystrophy.
Volume: 19
Pages: 100664
Publication
First Author: Cavallari E
Year: 2018
Journal: Sci Rep
Title: The 13C hyperpolarized pyruvate generated by ParaHydrogen detects the response of the heart to altered metabolism in real time.
Volume: 8
Issue: 1
Pages: 8366
Publication
First Author: Aguado J
Year: 2019
Journal: Nat Commun
Title: Inhibition of DNA damage response at telomeres improves the detrimental phenotypes of Hutchinson-Gilford Progeria Syndrome.
Volume: 10
Issue: 1
Pages: 4990
Publication
First Author: McKenna T
Year: 2014
Journal: Aging Cell
Title: Embryonic expression of the common progeroid lamin A splice mutation arrests postnatal skin development.
Volume: 13
Issue: 2
Pages: 292-302
Publication
First Author: Schmidt E
Year: 2012
Journal: J Biol Chem
Title: Expression of the Hutchinson-Gilford progeria mutation during osteoblast development results in loss of osteocytes, irregular mineralization, and poor biomechanical properties.
Volume: 287
Issue: 40
Pages: 33512-22
Publication
First Author: Yang SH
Year: 2011
Journal: Hum Mol Genet
Title: Absence of progeria-like disease phenotypes in knock-in mice expressing a non-farnesylated version of progerin.
Volume: 20
Issue: 3
Pages: 436-44
Publication
First Author: Rosengardten Y
Year: 2011
Journal: Aging Cell
Title: Stem cell depletion in Hutchinson-Gilford progeria syndrome.
Volume: 10
Issue: 6
Pages: 1011-20
Publication
First Author: Benedicto I
Year: 2024
Journal: Proc Natl Acad Sci U S A
Title: Exacerbated atherosclerosis in progeria is prevented by progerin elimination in vascular smooth muscle cells but not endothelial cells.
Volume: 121
Issue: 18
Pages: e2400752121
Publication
First Author: Kubben N
Year: 2012
Journal: Chromosoma
Title: Mapping of lamin A- and progerin-interacting genome regions.
Volume: 121
Issue: 5
Pages: 447-64
Publication
First Author: von Kleeck R
Year: 2021
Journal: Sci Rep
Title: Decreased vascular smooth muscle contractility in Hutchinson-Gilford Progeria Syndrome linked to defective smooth muscle myosin heavy chain expression.
Volume: 11
Issue: 1
Pages: 10625
Publication
First Author: Villa-Bellosta R
Year: 2020
Journal: EMBO Mol Med
Title: Dietary magnesium supplementation improves lifespan in a mouse model of progeria.
Volume: 12
Issue: 10
Pages: e12423
Publication
First Author: Della Valle F
Year: 2022
Journal: Sci Transl Med
Title: LINE-1 RNA causes heterochromatin erosion and is a target for amelioration of senescent phenotypes in progeroid syndromes.
Volume: 14
Issue: 657
Pages: eabl6057
Publication  
First Author: von Kleeck R
Year: 2021
Journal: Life Sci Alliance
Title: Arterial stiffness and cardiac dysfunction in Hutchinson-Gilford Progeria Syndrome corrected by inhibition of lysyl oxidase.
Volume: 4
Issue: 5
Publication
First Author: Choudhury D
Year: 2022
Journal: Cell Rep
Title: Inhibition of glutaminolysis restores mitochondrial function in senescent stem cells.
Volume: 41
Issue: 9
Pages: 111744
Publication
First Author: Villa-Bellosta R
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: ATP-based therapy prevents vascular calcification and extends longevity in a mouse model of Hutchinson-Gilford progeria syndrome.
Volume: 116
Issue: 47
Pages: 23698-23704
Publication
First Author: Kang SM
Year: 2021
Journal: Commun Biol
Title: Progerinin, an optimized progerin-lamin A binding inhibitor, ameliorates premature senescence phenotypes of Hutchinson-Gilford progeria syndrome.
Volume: 4
Issue: 1
Pages: 5
Publication
First Author: Squarzoni S
Year: 2021
Journal: Aging Cell
Title: Interleukin-6 neutralization ameliorates symptoms in prematurely aged mice.
Volume: 20
Issue: 1
Pages: e13285
Publication
First Author: Sahu SK
Year: 2024
Journal: Sci Transl Med
Title: Targeted partial reprogramming of age-associated cell states improves markers of health in mouse models of aging.
Volume: 16
Issue: 764
Pages: eadg1777
Publication
First Author: Vidak S
Year: 2023
Journal: Cell Rep
Title: Activation of endoplasmic reticulum stress in premature aging via the inner nuclear membrane protein SUN2.
Volume: 42
Issue: 5
Pages: 112534
Publication
First Author: Macías Á
Year: 2022
Journal: Cardiovasc Res
Title: Paclitaxel mitigates structural alterations and cardiac conduction system defects in a mouse model of Hutchinson-Gilford progeria syndrome.
Volume: 118
Issue: 2
Pages: 503-516
Publication
First Author: Viggars MR
Year: 2023
Journal: Am J Physiol Cell Physiol
Title: PCM1 labeling reveals myonuclear and nuclear dynamics in skeletal muscle across species.
Volume: 324
Issue: 1
Pages: C85-C97
Publication
First Author: Cubria MB
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Evaluation of musculoskeletal phenotype of the G608G progeria mouse model with lonafarnib, pravastatin, and zoledronic acid as treatment groups.
Volume: 117
Issue: 22
Pages: 12029-12040
Publication  
First Author: Kim PH
Year: 2021
Journal: JCI Insight
Title: Nuclear membrane ruptures underlie the vascular pathology in a mouse model of Hutchinson-Gilford progeria syndrome.
Volume: 6
Issue: 16
Publication
First Author: Link J
Year: 2013
Journal: PLoS Genet
Title: The meiotic nuclear lamina regulates chromosome dynamics and promotes efficient homologous recombination in the mouse.
Volume: 9
Issue: 1
Pages: e1003261
Publication
First Author: Koncicka M
Year: 2020
Journal: PLoS One
Title: Expression of lamin C2 in mammalian oocytes.
Volume: 15
Issue: 4
Pages: e0229781
Publication
First Author: Chen Y
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Impaired end joining induces cardiac atrophy in a Hutchinson-Gilford progeria mouse model.
Volume: 120
Issue: 47
Pages: e2309200120
Publication
First Author: Hu Q
Year: 2023
Journal: EMBO J
Title: Anti-hsa-miR-59 alleviates premature senescence associated with Hutchinson-Gilford progeria syndrome in mice.
Volume: 42
Issue: 1
Pages: e110937
Publication
First Author: Wu Y
Year: 2024
Journal: Biochim Biophys Acta Mol Basis Dis
Title: LMNA-related muscular dystrophy involving myoblast proliferation and apoptosis through the FOXO1/GADD45A pathway.
Volume: 1870
Issue: 2
Pages: 166943
Publication
First Author: Lee JS
Year: 2007
Journal: Biophys J
Title: Nuclear lamin A/C deficiency induces defects in cell mechanics, polarization, and migration.
Volume: 93
Issue: 7
Pages: 2542-52
Publication
First Author: Wilson KL
Year: 2000
Journal: Trends Cell Biol
Title: The nuclear envelope, muscular dystrophy and gene expression.
Volume: 10
Issue: 4
Pages: 125-9
Publication
First Author: Lammerding J
Year: 2004
Journal: J Clin Invest
Title: Lamin A/C deficiency causes defective nuclear mechanics and mechanotransduction.
Volume: 113
Issue: 3
Pages: 370-8
Publication
First Author: Lammerding J
Year: 2006
Journal: J Biol Chem
Title: Lamins A and C but not lamin B1 regulate nuclear mechanics.
Volume: 281
Issue: 35
Pages: 25768-80
Publication
First Author: Capanni C
Year: 2008
Journal: Exp Cell Res
Title: Prelamin A is involved in early steps of muscle differentiation.
Volume: 314
Issue: 20
Pages: 3628-37
Publication
First Author: Polychronidou M
Year: 2010
Journal: Mol Biol Cell
Title: Farnesylated nuclear proteins Kugelkern and lamin Dm0 affect nuclear morphology by directly interacting with the nuclear membrane.
Volume: 21
Issue: 19
Pages: 3409-20
Publication
First Author: Zuo B
Year: 2012
Journal: Biol Open
Title: Influences of lamin A levels on induction of pluripotent stem cells.
Volume: 1
Issue: 11
Pages: 1118-27
Publication
First Author: Sehgal P
Year: 2013
Journal: PLoS One
Title: Lamin A/C haploinsufficiency modulates the differentiation potential of mouse embryonic stem cells.
Volume: 8
Issue: 2
Pages: e57891
Publication
First Author: Swift J
Year: 2013
Journal: Science
Title: Nuclear lamin-A scales with tissue stiffness and enhances matrix-directed differentiation.
Volume: 341
Issue: 6149
Pages: 1240104
Publication
First Author: Harr JC
Year: 2015
Journal: J Cell Biol
Title: Directed targeting of chromatin to the nuclear lamina is mediated by chromatin state and A-type lamins.
Volume: 208
Issue: 1
Pages: 33-52
Publication  
First Author: de la Rosa J
Year: 2013
Journal: Nat Commun
Title: Prelamin A causes progeria through cell-extrinsic mechanisms and prevents cancer invasion.
Volume: 4
Pages: 2268
Publication
First Author: Toribio-Fernández R
Year: 2019
Journal: J Pathol
Title: Lamin A/C deficiency in CD4+ T-cells enhances regulatory T-cells and prevents inflammatory bowel disease.
Volume: 249
Issue: 4
Pages: 509-522
Publication
First Author: Manakanatas C
Year: 2022
Journal: Aging (Albany NY)
Title: Endothelial and systemic upregulation of miR-34a-5p fine-tunes senescence in progeria.
Volume: 14
Issue: 1
Pages: 195-224
Publication
First Author: Riedel W
Year: 1989
Journal: Biochim Biophys Acta
Title: Nucleotide sequence of the full-length mouse lamin C cDNA and its deduced amino-acid sequence.
Volume: 1008
Issue: 1
Pages: 119-22
Publication
First Author: Cohen TV
Year: 2013
Journal: Hum Mol Genet
Title: Defective skeletal muscle growth in lamin A/C-deficient mice is rescued by loss of Lap2α.
Volume: 22
Issue: 14
Pages: 2852-69
Publication
First Author: Ovadya Y
Year: 2018
Journal: Nat Commun
Title: Impaired immune surveillance accelerates accumulation of senescent cells and aging.
Volume: 9
Issue: 1
Pages: 5435
Publication
First Author: Kang SM
Year: 2021
Journal: Sci Rep
Title: Human WRN is an intrinsic inhibitor of progerin, abnormal splicing product of lamin A.
Volume: 11
Issue: 1
Pages: 9122
Publication
First Author: Naetar N
Year: 2008
Journal: Nat Cell Biol
Title: Loss of nucleoplasmic LAP2alpha-lamin A complexes causes erythroid and epidermal progenitor hyperproliferation.
Volume: 10
Issue: 11
Pages: 1341-8
Publication
First Author: Pilat U
Year: 2013
Journal: J Cell Sci
Title: The muscle dystrophy-causing ΔK32 lamin A/C mutant does not impair the functions of the nucleoplasmic lamin-A/C-LAP2α complex in mice.
Volume: 126
Issue: Pt 8
Pages: 1753-62
Publication  
First Author: Furusawa T
Year: 2015
Journal: Nat Commun
Title: Chromatin decompaction by the nucleosomal binding protein HMGN5 impairs nuclear sturdiness.
Volume: 6
Pages: 6138
Publication
First Author: Frock RL
Year: 2006
Journal: Genes Dev
Title: Lamin A/C and emerin are critical for skeletal muscle satellite cell differentiation.
Volume: 20
Issue: 4
Pages: 486-500
Publication
First Author: Smith ER
Year: 2017
Journal: BMC Cell Biol
Title: Nuclear envelope structural proteins facilitate nuclear shape changes accompanying embryonic differentiation and fidelity of gene expression.
Volume: 18
Issue: 1
Pages: 8
Publication
First Author: Bárcena C
Year: 2019
Journal: Nat Med
Title: Healthspan and lifespan extension by fecal microbiota transplantation into progeroid mice.
Volume: 25
Issue: 8
Pages: 1234-1242
Publication
First Author: Bárcena C
Year: 2018
Journal: Cell Rep
Title: Methionine Restriction Extends Lifespan in Progeroid Mice and Alters Lipid and Bile Acid Metabolism.
Volume: 24
Issue: 9
Pages: 2392-2403
Publication
First Author: Liu B
Year: 2005
Journal: Nat Med
Title: Genomic instability in laminopathy-based premature aging.
Volume: 11
Issue: 7
Pages: 780-5
Publication
First Author: Swahari V
Year: 2024
Journal: Commun Biol
Title: miR-29 is an important driver of aging-related phenotypes.
Volume: 7
Issue: 1
Pages: 1055
Publication
First Author: Sánchez-López A
Year: 2021
Journal: Circulation
Title: Cardiovascular Progerin Suppression and Lamin A Restoration Rescue Hutchinson-Gilford Progeria Syndrome.
Volume: 144
Issue: 22
Pages: 1777-1794
Publication    
First Author: Chen X
Year: 2021
Journal: Elife
Title: A small-molecule ICMT inhibitor delays senescence of Hutchinson-Gilford progeria syndrome cells.
Volume: 10
Publication
First Author: Pitrez PR
Year: 2020
Journal: Nat Commun
Title: Vulnerability of progeroid smooth muscle cells to biomechanical forces is mediated by MMP13.
Volume: 11
Issue: 1
Pages: 4110
Publication      
First Author: Li G
Year: 2022
Journal: J Invest Dermatol
Title: Aging-Conferred SIRT7 Decline Inhibits Rosacea-Like Skin Inflammation by Modulating Toll-Like Receptor 2‒NF-κB Signaling.
Publication
First Author: Lattanzi G
Year: 2003
Journal: Biochem Biophys Res Commun
Title: Association of emerin with nuclear and cytoplasmic actin is regulated in differentiating myoblasts.
Volume: 303
Issue: 3
Pages: 764-70
Publication
First Author: Vecerová J
Year: 2004
Journal: Mol Biol Cell
Title: Formation of nuclear splicing factor compartments is independent of lamins A/C.
Volume: 15
Issue: 11
Pages: 4904-10
Publication
First Author: Mariappan I
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Identification of cyclin D3 as a new interaction partner of lamin A/C.
Volume: 355
Issue: 4
Pages: 981-5
Publication
First Author: Han X
Year: 2008
Journal: Nat Cell Biol
Title: Tethering by lamin A stabilizes and targets the ING1 tumour suppressor.
Volume: 10
Issue: 11
Pages: 1333-40
Publication
First Author: Oh YS
Year: 2010
Journal: Aging Cell
Title: Downregulation of lamin A by tumor suppressor AIMP3/p18 leads to a progeroid phenotype in mice.
Volume: 9
Issue: 5
Pages: 810-22
Publication
First Author: González-Granado JM
Year: 2014
Journal: PLoS One
Title: Sorting nexin 6 enhances lamin a synthesis and incorporation into the nuclear envelope.
Volume: 9
Issue: 12
Pages: e115571