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Search results 101 to 200 out of 476 for P2rx7

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Category: Publication
Type Details Score
Publication  
First Author: Albalawi F
Year: 2017
Journal: Front Cell Neurosci
Title: The P2X7 Receptor Primes IL-1β and the NLRP3 Inflammasome in Astrocytes Exposed to Mechanical Strain.
Volume: 11
Pages: 227
Publication
First Author: Sánchez-Nogueiro J
Year: 2005
Journal: FEBS Lett
Title: Characterization of a functional P2X(7)-like receptor in cerebellar granule neurons from P2X(7) knockout mice.
Volume: 579
Issue: 17
Pages: 3783-8
Publication
First Author: Bulanova E
Year: 2009
Journal: J Leukoc Biol
Title: ATP induces P2X7 receptor-independent cytokine and chemokine expression through P2X1 and P2X3 receptors in murine mast cells.
Volume: 85
Issue: 4
Pages: 692-702
Publication
First Author: Huang L
Year: 2023
Journal: iScience
Title: P2X7 purinergic receptor modulates dentate gyrus excitatory neurotransmission and alleviates schizophrenia-like symptoms in mouse.
Volume: 26
Issue: 9
Pages: 107560
Publication
First Author: Mut-Arbona P
Year: 2023
Journal: J Neurosci
Title: Dual Role of the P2X7 Receptor in Dendritic Outgrowth during Physiological and Pathological Brain Development.
Volume: 43
Issue: 7
Pages: 1125-1142
Publication
First Author: Aswad F
Year: 2006
Journal: Cell Immunol
Title: P2X7 receptor expression levels determine lethal effects of a purine based danger signal in T lymphocytes.
Volume: 243
Issue: 1
Pages: 58-65
Publication
First Author: Sim JA
Year: 2004
Journal: J Neurosci
Title: Reanalysis of P2X7 receptor expression in rodent brain.
Volume: 24
Issue: 28
Pages: 6307-14
Publication
First Author: Magnaghi V
Year: 2021
Journal: Eur J Neurosci
Title: Peripheral nerve regeneration following injury is altered in mice lacking P2X7 receptor.
Volume: 54
Issue: 5
Pages: 5798-5814
Publication
First Author: Mayo C
Year: 2008
Journal: Invest Ophthalmol Vis Sci
Title: Regulation by P2X7: epithelial migration and stromal organization in the cornea.
Volume: 49
Issue: 10
Pages: 4384-91
Publication  
First Author: Domingos LB
Year: 2018
Journal: Neuropharmacology
Title: P2X7 purinergic receptors participate in the expression and extinction processes of contextual fear conditioning memory in mice.
Volume: 128
Pages: 474-481
Publication  
First Author: Bernardazzi C
Year: 2022
Journal: Int J Mol Sci
Title: The P2X7 Receptor Promotes Colorectal Inflammation and Tumorigenesis by Modulating Gut Microbiota and the Inflammasome.
Volume: 23
Issue: 9
Publication  
First Author: Vieira FS
Year: 2016
Journal: Mol Cell Endocrinol
Title: P2X7 receptor knockout prevents streptozotocin-induced type 1 diabetes in mice.
Volume: 419
Pages: 148-57
Publication
First Author: Ke HZ
Year: 2003
Journal: Mol Endocrinol
Title: Deletion of the P2X7 nucleotide receptor reveals its regulatory roles in bone formation and resorption.
Volume: 17
Issue: 7
Pages: 1356-67
Publication
First Author: Darville T
Year: 2007
Journal: J Immunol
Title: Effect of the purinergic receptor P2X7 on Chlamydia infection in cervical epithelial cells and vaginally infected mice.
Volume: 179
Issue: 6
Pages: 3707-14
Publication
First Author: Figliuolo VR
Year: 2017
Journal: Biochim Biophys Acta
Title: P2X7 receptor promotes intestinal inflammation in chemically induced colitis and triggers death of mucosal regulatory T cells.
Volume: 1863
Issue: 6
Pages: 1183-1194
Publication  
First Author: Noronha LPT
Year: 2023
Journal: Front Cell Infect Microbiol
Title: Cysteinyl-leukotrienes promote cutaneous Leishmaniasis control.
Volume: 13
Pages: 1192800
Publication  
First Author: Campos RC
Year: 2014
Journal: Neuroscience
Title: Pharmacological blockage and P2X7 deletion hinder aversive memories: reversion in an enriched environment.
Volume: 280
Pages: 220-30
Publication
First Author: da Silva AA
Year: 2022
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Parental obesity alters offspring blood pressure regulation and cardiovascular responses to stress: role of P2X7R and sex differences.
Volume: 322
Issue: 5
Pages: R421-R433
Publication  
First Author: Alves VS
Year: 2023
Journal: Front Pharmacol
Title: P2X7 receptor contributes to long-term neuroinflammation and cognitive impairment in sepsis-surviving mice.
Volume: 14
Pages: 1179723
Publication
First Author: Lee BH
Year: 2012
Journal: PLoS One
Title: Activation of P2X(7) receptor by ATP plays an important role in regulating inflammatory responses during acute viral infection.
Volume: 7
Issue: 4
Pages: e35812
Publication
First Author: Garcia-Marcos M
Year: 2005
Journal: FEBS Lett
Title: Role of sodium in mitochondrial membrane depolarization induced by P2X7 receptor activation in submandibular glands.
Volume: 579
Issue: 24
Pages: 5407-13
Publication
First Author: Aswad F
Year: 2005
Journal: J Immunol
Title: High sensitivity of CD4+CD25+ regulatory T cells to extracellular metabolites nicotinamide adenine dinucleotide and ATP: a role for P2X7 receptors.
Volume: 175
Issue: 5
Pages: 3075-83
Publication
First Author: Beaucage KL
Year: 2014
Journal: Purinergic Signal
Title: Loss of P2X7 nucleotide receptor function leads to abnormal fat distribution in mice.
Volume: 10
Issue: 2
Pages: 291-304
Publication  
First Author: Toledo C
Year: 2022
Journal: EBioMedicine
Title: Medullary astrocytes mediate irregular breathing patterns generation in chronic heart failure through purinergic P2X7 receptor signalling.
Volume: 80
Pages: 104044
Publication
First Author: Wang AYM
Year: 2021
Journal: Sci Rep
Title: Retinal ganglion cell dysfunction in mice following acute intraocular pressure is exacerbated by P2X7 receptor knockout.
Volume: 11
Issue: 1
Pages: 4184
Publication
First Author: Witting A
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Experimental autoimmune encephalomyelitis disrupts endocannabinoid-mediated neuroprotection.
Volume: 103
Issue: 16
Pages: 6362-7
Publication
First Author: Vergani A
Year: 2013
Journal: Diabetes
Title: Effect of the purinergic inhibitor oxidized ATP in a model of islet allograft rejection.
Volume: 62
Issue: 5
Pages: 1665-75
Publication
First Author: Habbas S
Year: 2011
Journal: Glia
Title: Purinergic signaling in the cerebellum: Bergmann glial cells express functional ionotropic P2X7 receptors.
Volume: 59
Issue: 12
Pages: 1800-12
Publication
First Author: Masin M
Year: 2012
Journal: Br J Pharmacol
Title: Expression, assembly and function of novel C-terminal truncated variants of the mouse P2X7 receptor: re-evaluation of P2X7 knockouts.
Volume: 165
Issue: 4
Pages: 978-93
Publication
First Author: Amaral EP
Year: 2014
Journal: PLoS Pathog
Title: Pulmonary infection with hypervirulent Mycobacteria reveals a crucial role for the P2X7 receptor in aggressive forms of tuberculosis.
Volume: 10
Issue: 7
Pages: e1004188
Publication
First Author: Vessey KA
Year: 2017
Journal: Am J Pathol
Title: Loss of Function of P2X7 Receptor Scavenger Activity in Aging Mice: A Novel Model for Investigating the Early Pathogenesis of Age-Related Macular Degeneration.
Volume: 187
Issue: 8
Pages: 1670-1685
Publication
First Author: Furlan-Freguia C
Year: 2011
Journal: J Clin Invest
Title: P2X7 receptor signaling contributes to tissue factor-dependent thrombosis in mice.
Volume: 121
Issue: 7
Pages: 2932-44
Publication
First Author: Santana PT
Year: 2015
Journal: J Innate Immun
Title: The P2X7 Receptor Contributes to the Development of the Exacerbated Inflammatory Response Associated with Sepsis.
Volume: 7
Issue: 4
Pages: 417-27
Publication
First Author: Vessey KA
Year: 2012
Journal: PLoS One
Title: Rod and cone pathway signalling is altered in the P2X7 receptor knock out mouse.
Volume: 7
Issue: 1
Pages: e29990
Publication
First Author: Li J
Year: 2005
Journal: J Biol Chem
Title: The P2X7 nucleotide receptor mediates skeletal mechanotransduction.
Volume: 280
Issue: 52
Pages: 42952-9
Publication  
First Author: Falco MV
Year: 2023
Journal: Front Cell Neurosci
Title: P2X7 receptor activation awakes a dormant stem cell niche in the adult spinal cord.
Volume: 17
Pages: 1288676
Publication  
First Author: Mankus C
Year: 2012
Journal: Mol Vis
Title: The P2X(7) receptor regulates proteoglycan expression in the corneal stroma.
Volume: 18
Pages: 128-38
Publication  
First Author: Boucher AA
Year: 2011
Journal: Neuroscience
Title: Resilience and reduced c-Fos expression in P2X7 receptor knockout mice exposed to repeated forced swim test.
Volume: 189
Pages: 170-7
Publication
First Author: Eltom S
Year: 2011
Journal: PLoS One
Title: P2X7 receptor and caspase 1 activation are central to airway inflammation observed after exposure to tobacco smoke.
Volume: 6
Issue: 9
Pages: e24097
Publication  
First Author: Lis-López L
Year: 2023
Journal: Int J Mol Sci
Title: P2X7 Receptor Regulates Collagen Expression in Human Intestinal Fibroblasts: Relevance in Intestinal Fibrosis.
Volume: 24
Issue: 16
Publication
First Author: Müller T
Year: 2011
Journal: Am J Respir Cell Mol Biol
Title: A potential role for P2X7R in allergic airway inflammation in mice and humans.
Volume: 44
Issue: 4
Pages: 456-64
Publication
First Author: Adriouch S
Year: 2002
Journal: J Immunol
Title: Cutting edge: a natural P451L mutation in the cytoplasmic domain impairs the function of the mouse P2X7 receptor.
Volume: 169
Issue: 8
Pages: 4108-12
Publication
First Author: Basso AM
Year: 2009
Journal: Behav Brain Res
Title: Behavioral profile of P2X7 receptor knockout mice in animal models of depression and anxiety: relevance for neuropsychiatric disorders.
Volume: 198
Issue: 1
Pages: 83-90
Publication
First Author: Sikora A
Year: 1999
Journal: J Immunol
Title: Cutting edge: purinergic signaling regulates radical-mediated bacterial killing mechanisms in macrophages through a P2X7-independent mechanism.
Volume: 163
Issue: 2
Pages: 558-61
Publication
First Author: Adinolfi E
Year: 2015
Journal: Cancer Res
Title: Accelerated tumor progression in mice lacking the ATP receptor P2X7.
Volume: 75
Issue: 4
Pages: 635-44
Publication
First Author: Wang N
Year: 2018
Journal: Sci Rep
Title: P2X7 receptor regulates osteoclast function and bone loss in a mouse model of osteoporosis.
Volume: 8
Issue: 1
Pages: 3507
Publication
First Author: Xu XJ
Year: 2012
Journal: J Cell Sci
Title: Splice variants of the P2X7 receptor reveal differential agonist dependence and functional coupling with pannexin-1.
Volume: 125
Issue: Pt 16
Pages: 3776-89
Publication
First Author: Chiozzi P
Year: 2019
Journal: Sci Rep
Title: Amyloid β-dependent mitochondrial toxicity in mouse microglia requires P2X7 receptor expression and is prevented by nimodipine.
Volume: 9
Issue: 1
Pages: 6475
Publication
First Author: Chessell IP
Year: 2005
Journal: Pain
Title: Disruption of the P2X7 purinoceptor gene abolishes chronic inflammatory and neuropathic pain.
Volume: 114
Issue: 3
Pages: 386-96
Publication
First Author: Taylor SR
Year: 2009
Journal: J Am Soc Nephrol
Title: P2X7 deficiency attenuates renal injury in experimental glomerulonephritis.
Volume: 20
Issue: 6
Pages: 1275-81
Publication  
First Author: Syberg S
Year: 2012
Journal: J Osteoporos
Title: Genetic Background Strongly Influences the Bone Phenotype of P2X7 Receptor Knockout Mice.
Volume: 2012
Pages: 391097
Publication
First Author: Hamilton N
Year: 2008
Journal: Glia
Title: Mechanisms of ATP- and glutamate-mediated calcium signaling in white matter astrocytes.
Volume: 56
Issue: 7
Pages: 734-49
Publication
First Author: Wu D
Year: 2018
Journal: J Neurosci
Title: Intraneural Injection of ATP Stimulates Regeneration of Primary Sensory Axons in the Spinal Cord.
Volume: 38
Issue: 6
Pages: 1351-1365
Publication
First Author: Lucattelli M
Year: 2011
Journal: Am J Respir Cell Mol Biol
Title: P2X7 receptor signaling in the pathogenesis of smoke-induced lung inflammation and emphysema.
Volume: 44
Issue: 3
Pages: 423-9
Publication
First Author: Keating C
Year: 2011
Journal: J Immunol
Title: P2X7 receptor-dependent intestinal afferent hypersensitivity in a mouse model of postinfectious irritable bowel syndrome.
Volume: 187
Issue: 3
Pages: 1467-74
Publication
First Author: Bianchi C
Year: 2023
Journal: Alzheimers Res Ther
Title: P2X7 receptor inhibition ameliorates ubiquitin-proteasome system dysfunction associated with Alzheimer's disease.
Volume: 15
Issue: 1
Pages: 105
Publication  
First Author: Conte G
Year: 2021
Journal: Cells
Title: Circulating P2X7 Receptor Signaling Components as Diagnostic Biomarkers for Temporal Lobe Epilepsy.
Volume: 10
Issue: 9
Publication    
First Author: Li C
Year: 2024
Journal: Adv Sci (Weinh)
Title: The eATP/P2×7R Axis Drives Quantum Dot-Nanoparticle Induced Neutrophil Recruitment in the Pulmonary Microcirculation.
Pages: e2404661
Publication      
First Author: Jooss T
Year: 2023
Journal: Mucosal Immunol
Title: Macrophages and glia are the dominant P2X7-expressing cell types in the gut nervous system-No evidence for the role of neuronal P2X7 receptors in colitis.
Publication
First Author: Morgan J
Year: 2023
Journal: Epilepsia
Title: Increased uptake of the P2X7 receptor radiotracer (18) F-JNJ-64413739 in the brain and peripheral organs according to the severity of status epilepticus in male mice.
Volume: 64
Issue: 2
Pages: 511-523
Publication  
First Author: Conte G
Year: 2020
Journal: Front Mol Neurosci
Title: P2X7 Receptor-Dependent microRNA Expression Profile in the Brain Following Status Epilepticus in Mice.
Volume: 13
Pages: 127
Publication
First Author: Papp L
Year: 2007
Journal: Biochem Biophys Res Commun
Title: P2X7 receptor mediated phosphorylation of p38MAP kinase in the hippocampus.
Volume: 355
Issue: 2
Pages: 568-74
Publication
First Author: Lu H
Year: 2007
Journal: Biochem Biophys Res Commun
Title: P2X7 receptors mediate NADH transport across the plasma membranes of astrocytes.
Volume: 362
Issue: 4
Pages: 946-50
Publication
First Author: Denlinger LC
Year: 2001
Journal: J Immunol
Title: Cutting edge: the nucleotide receptor P2X7 contains multiple protein- and lipid-interaction motifs including a potential binding site for bacterial lipopolysaccharide.
Volume: 167
Issue: 4
Pages: 1871-6
Publication
First Author: Pfeiffer ZA
Year: 2007
Journal: Free Radic Biol Med
Title: Nucleotide receptor signaling in murine macrophages is linked to reactive oxygen species generation.
Volume: 42
Issue: 10
Pages: 1506-16
Publication
First Author: Paukert M
Year: 2002
Journal: FEBS Lett
Title: The P2X(7) receptor from Xenopus laevis: formation of a large pore in Xenopus oocytes.
Volume: 513
Issue: 2-3
Pages: 253-8
Publication
First Author: Bulanova E
Year: 2005
Journal: J Immunol
Title: Extracellular ATP induces cytokine expression and apoptosis through P2X7 receptor in murine mast cells.
Volume: 174
Issue: 7
Pages: 3880-90
Publication
First Author: Moore SF
Year: 2008
Journal: Biochem Pharmacol
Title: Species and agonist dependent zinc modulation of endogenous and recombinant ATP-gated P2X7 receptors.
Volume: 76
Issue: 12
Pages: 1740-7
Publication
First Author: Takenouchi T
Year: 2009
Journal: J Immunol
Title: The activation of P2X7 receptor impairs lysosomal functions and stimulates the release of autophagolysosomes in microglial cells.
Volume: 182
Issue: 4
Pages: 2051-62
Publication
First Author: Díaz-Hernandez M
Year: 2008
Journal: J Cell Sci
Title: Inhibition of the ATP-gated P2X7 receptor promotes axonal growth and branching in cultured hippocampal neurons.
Volume: 121
Issue: Pt 22
Pages: 3717-28
Publication
First Author: Scheuplein F
Year: 2009
Journal: J Immunol
Title: NAD+ and ATP released from injured cells induce P2X7-dependent shedding of CD62L and externalization of phosphatidylserine by murine T cells.
Volume: 182
Issue: 5
Pages: 2898-908
Publication
First Author: Sanz JM
Year: 2009
Journal: J Immunol
Title: Activation of microglia by amyloid {beta} requires P2X7 receptor expression.
Volume: 182
Issue: 7
Pages: 4378-85
Publication
First Author: Gómez-Villafuertes R
Year: 2009
Journal: FEBS J
Title: Ca2+/calmodulin-dependent kinase II signalling cascade mediates P2X7 receptor-dependent inhibition of neuritogenesis in neuroblastoma cells.
Volume: 276
Issue: 18
Pages: 5307-25
Publication
First Author: Lees MP
Year: 2010
Journal: J Immunol
Title: P2X7 receptor-mediated killing of an intracellular parasite, Toxoplasma gondii, by human and murine macrophages.
Volume: 184
Issue: 12
Pages: 7040-6
Publication
First Author: Constantinescu P
Year: 2010
Journal: Biochim Biophys Acta
Title: P2X7 receptor activation induces cell death and microparticle release in murine erythroleukemia cells.
Volume: 1798
Issue: 9
Pages: 1797-804
Publication
First Author: Okuda H
Year: 2010
Journal: Glia
Title: Contribution of P2X7 receptors to adenosine uptake by cultured mouse astrocytes.
Volume: 58
Issue: 14
Pages: 1757-65
Publication
First Author: Pettengill MA
Year: 2012
Journal: Infect Immun
Title: Reversible inhibition of Chlamydia trachomatis infection in epithelial cells due to stimulation of P2X(4) receptors.
Volume: 80
Issue: 12
Pages: 4232-8
Publication
First Author: Shieh CH
Year: 2014
Journal: Glia
Title: P2X7-dependent, but differentially regulated release of IL-6, CCL2, and TNF-α in cultured mouse microglia.
Volume: 62
Issue: 4
Pages: 592-607
Publication
First Author: Kumagai S
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Cathelicidin antimicrobial peptide inhibits fibroblast migration via P2X7 receptor signaling.
Volume: 437
Issue: 4
Pages: 609-14
Publication
First Author: Yamamoto M
Year: 2013
Journal: Biochem Biophys Res Commun
Title: P2X7 receptors regulate engulfing activity of non-stimulated resting astrocytes.
Volume: 439
Issue: 1
Pages: 90-5
Publication
First Author: Robinson LE
Year: 2014
Journal: J Biol Chem
Title: Plasma membrane cholesterol as a regulator of human and rodent P2X7 receptor activation and sensitization.
Volume: 289
Issue: 46
Pages: 31983-94
Publication
First Author: Yan Y
Year: 2015
Journal: Am J Physiol Cell Physiol
Title: P2X7 receptor inhibition protects against ischemic acute kidney injury in mice.
Volume: 308
Issue: 6
Pages: C463-72
Publication
First Author: Gao L
Year: 2018
Journal: Neuroreport
Title: The effects of P2X7 receptor knockout on emotional conditions over the lifespan of mice.
Volume: 29
Issue: 17
Pages: 1479-1486
Publication
First Author: Gao L
Year: 2019
Journal: Neuroreport
Title: Age-specific effects of P2X7 receptors on olfactory function in mice.
Volume: 30
Issue: 16
Pages: 1055-1061
Publication  
First Author: He X
Year: 2021
Journal: J Clin Invest
Title: Bone marrow niche ATP levels determine leukemia-initiating cell activity via P2X7 in leukemic models.
Volume: 131
Issue: 4
Publication
First Author: Kaiser M
Year: 2016
Journal: Purinergic Signal
Title: Lack of functional P2X7 receptor aggravates brain edema development after middle cerebral artery occlusion.
Volume: 12
Issue: 3
Pages: 453-63
Publication  
First Author: Liu YH
Year: 2018
Journal: Front Cell Infect Microbiol
Title: The ATP-P2X7 Signaling Axis Is an Essential Sentinel for Intracellular Clostridium difficile Pathogen-Induced Inflammasome Activation.
Volume: 8
Pages: 84
Publication
First Author: Brock VJ
Year: 2022
Journal: Sci Adv
Title: P2X4 and P2X7 are essential players in basal T cell activity and Ca2+ signaling milliseconds after T cell activation.
Volume: 8
Issue: 5
Pages: eabl9770
Publication
First Author: Tsai SH
Year: 2015
Journal: Immunity
Title: The ectoenzyme E-NPP3 negatively regulates ATP-dependent chronic allergic responses by basophils and mast cells.
Volume: 42
Issue: 2
Pages: 279-293
Publication
First Author: Cicko S
Year: 2018
Journal: Oncotarget
Title: Extracellular ATP is a danger signal activating P2X7 receptor in a LPS mediated inflammation (ARDS/ALI).
Volume: 9
Issue: 55
Pages: 30635-30648
Publication  
First Author: Messemer N
Year: 2013
Journal: Neuropharmacology
Title: P2X7 receptors at adult neural progenitor cells of the mouse subventricular zone.
Volume: 73
Pages: 122-37
Publication  
First Author: Brock VJ
Year: 2024
Journal: Front Immunol
Title: Time-resolved role of P2X4 and P2X7 during CD8(+) T cell activation.
Volume: 15
Pages: 1258119
Publication
First Author: Behr FM
Year: 2020
Journal: Nat Immunol
Title: Tissue-resident memory CD8+ T cells shape local and systemic secondary T cell responses.
Volume: 21
Issue: 9
Pages: 1070-1081
Publication
First Author: Ebeling G
Year: 2014
Journal: PLoS One
Title: Effect of P2X7 receptor knockout on AQP-5 expression of type I alveolar epithelial cells.
Volume: 9
Issue: 6
Pages: e100282
Publication
First Author: Heiss K
Year: 2008
Journal: J Immunol
Title: High sensitivity of intestinal CD8+ T cells to nucleotides indicates P2X7 as a regulator for intestinal T cell responses.
Volume: 181
Issue: 6
Pages: 3861-9
Publication
First Author: Kawamura H
Year: 2012
Journal: Immunology
Title: Extracellular ATP-stimulated macrophages produce macrophage inflammatory protein-2 which is important for neutrophil migration.
Volume: 136
Issue: 4
Pages: 448-58
Publication
First Author: Yoshida K
Year: 2020
Journal: J Immunol
Title: Extracellular ATP Augments Antigen-Induced Murine Mast Cell Degranulation and Allergic Responses via P2X4 Receptor Activation.
Volume: 204
Issue: 12
Pages: 3077-3085
Publication
First Author: Boumechache M
Year: 2009
Journal: J Biol Chem
Title: Analysis of assembly and trafficking of native P2X4 and P2X7 receptor complexes in rodent immune cells.
Volume: 284
Issue: 20
Pages: 13446-54
Publication
First Author: Brône B
Year: 2007
Journal: Immunol Lett
Title: P2X currents in peritoneal macrophages of wild type and P2X4 -/- mice.
Volume: 113
Issue: 2
Pages: 83-9
Publication
First Author: Lordén G
Year: 2017
Journal: J Exp Med
Title: Lipin-2 regulates NLRP3 inflammasome by affecting P2X7 receptor activation.
Volume: 214
Issue: 2
Pages: 511-528