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Search results 101 to 200 out of 204 for Pcsk9

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Type Details Score
Publication
25613181 | J:217653
First Author: Wang X
Year: 2015
Journal: FEBS Lett
Title: MMP-2 inhibits PCSK9-induced degradation of the LDL receptor in Hepa1-c1c7 cells.
Volume: 589
Issue: 4
Pages: 490-6
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Publication
20080679 | J:157595
First Author: Love KT
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Lipid-like materials for low-dose, in vivo gene silencing.
Volume: 107
Issue: 5
Pages: 1864-9
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Publication
20566868 | J:162071
First Author: Tan XJ
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Liver X receptor beta and thyroid hormone receptor alpha in brain cortical layering.
Volume: 107
Issue: 27
Pages: 12305-10
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Publication
18378686 | J:137555
First Author: Kim YI
Year: 2008
Journal: J Biol Chem
Title: CpG DNA prevents liver injury and shock-mediated death by modulating expression of interleukin-1 receptor-associated kinases.
Volume: 283
Issue: 22
Pages: 15258-70
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Publication
25446528 | J:218172
First Author: Ha T
Year: 2015
Journal: Dev Biol
Title: CbGRiTS: cerebellar gene regulation in time and space.
Volume: 397
Issue: 1
Pages: 18-30
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Publication
27146480 | J:233745
First Author: Ferrell JM
Year: 2016
Journal: J Lipid Res
Title: Cholesterol 7α-hydroxylase-deficient mice are protected from high-fat/high-cholesterol diet-induced metabolic disorders.
Volume: 57
Issue: 7
Pages: 1144-54
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Publication
26508642 | J:227474
First Author: Fonseca TL
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Perinatal deiodinase 2 expression in hepatocytes defines epigenetic susceptibility to liver steatosis and obesity.
Volume: 112
Issue: 45
Pages: 14018-23
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Publication
23362348 | J:194051
First Author: Heliot C
Year: 2013
Journal: Development
Title: HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2.
Volume: 140
Issue: 4
Pages: 873-85
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Publication
19501082 | J:152865
First Author: Georgas K
Year: 2009
Journal: Dev Biol
Title: Analysis of early nephron patterning reveals a role for distal RV proliferation in fusion to the ureteric tip via a cap mesenchyme-derived connecting segment.
Volume: 332
Issue: 2
Pages: 273-86
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Publication
21491542 | J:171615
First Author: Georgas KM
Year: 2011
Journal: Dev Dyn
Title: Expression of metanephric nephron-patterning genes in differentiating mesonephric tubules.
Volume: 240
Issue: 6
Pages: 1600-12
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16537572 | J:108241
First Author: Desai J
Year: 2006
Journal: Hum Mol Genet
Title: Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.
Volume: 15
Issue: 8
Pages: 1329-41
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Publication
24006456 | J:221550
First Author: Abonnenc M
Year: 2013
Journal: Circ Res
Title: Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.
Volume: 113
Issue: 10
Pages: 1138-47
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:342607
       
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
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Publication
- | J:77000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
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Publication
- | J:80001
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
18695239 | J:139707
First Author: Frank-Kamenetsky M
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates.
Volume: 105
Issue: 33
Pages: 11915-20
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Publication
19060325 | J:158079
First Author: Luo Y
Year: 2009
Journal: J Lipid Res
Title: Function and distribution of circulating human PCSK9 expressed extrahepatically in transgenic mice.
Volume: 50
Issue: 8
Pages: 1581-8
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Publication
30646909 | J:280156
First Author: Carreras A
Year: 2019
Journal: BMC Biol
Title: In vivo genome and base editing of a human PCSK9 knock-in hypercholesterolemic mouse model.
Volume: 17
Issue: 1
Pages: 4
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Publication
33177715 | J:300307
First Author: Liu X
Year: 2020
Journal: Nature
Title: Inhibition of PCSK9 potentiates immune checkpoint therapy for cancer.
Volume: 588
Issue: 7839
Pages: 693-698
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Publication
18197702 | J:132491
First Author: Fan D
Year: 2008
Journal: Biochemistry
Title: Self-association of human PCSK9 correlates with its LDLR-degrading activity.
Volume: 47
Issue: 6
Pages: 1631-9
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Publication
33523181 | J:306641
     
First Author: Rogers MA
Year: 2021
Journal: Cardiovasc Res
Title: Dynamin-related protein 1 inhibition reduces hepatic PCSK9 secretion.
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Publication
17449864 | J:122491
First Author: Qian YW
Year: 2007
Journal: J Lipid Res
Title: Secreted PCSK9 downregulates low density lipoprotein receptor through receptor-mediated endocytosis.
Volume: 48
Issue: 7
Pages: 1488-98
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Publication
33775647 | J:345188
 
First Author: Xu X
Year: 2021
Journal: Metabolism
Title: MiR-337-3p lowers serum LDL-C level through targeting PCSK9 in hyperlipidemic mice.
Volume: 119
Pages: 154768
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Publication
25258384 | J:216603
First Author: Ason B
Year: 2014
Journal: J Lipid Res
Title: PCSK9 inhibition fails to alter hepatic LDLR, circulating cholesterol, and atherosclerosis in the absence of ApoE.
Volume: 55
Issue: 11
Pages: 2370-9
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Publication
20448210 | J:180859
First Author: Herbert B
Year: 2010
Journal: Arterioscler Thromb Vasc Biol
Title: Increased secretion of lipoproteins in transgenic mice expressing human D374Y PCSK9 under physiological genetic control.
Volume: 30
Issue: 7
Pages: 1333-9
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Publication
37290532 | J:346045
First Author: Luan C
Year: 2023
Journal: J Biol Chem
Title: PCSK9 inhibition interrupts the cross-talk between keratinocytes and macrophages and prevents UVB-induced skin damage.
Volume: 299
Issue: 7
Pages: 104895
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Publication
17804797 | -
First Author: Hampton EN
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: The self-inhibited structure of full-length PCSK9 at 1.9 A reveals structural homology with resistin within the C-terminal domain.
Volume: 104
Issue: 37
Pages: 14604-9
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Publication
24440079 | -
First Author: Schroeder CI
Year: 2014
Journal: Chem Biol
Title: Design and synthesis of truncated EGF-A peptides that restore LDL-R recycling in the presence of PCSK9 in vitro.
Volume: 21
Issue: 2
Pages: 284-94
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27318830 | J:278772
 
First Author: Goettsch C
Year: 2016
Journal: Atherosclerosis
Title: A single injection of gain-of-function mutant PCSK9 adeno-associated virus vector induces cardiovascular calcification in mice with no genetic modification.
Volume: 251
Pages: 109-118
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34554110 | J:315694
First Author: Guo WJ
Year: 2021
Journal: Reproduction
Title: Contribution of high-fat diet-induced PCSK9 upregulation to a mouse model of PCOS is mediated partly by SREBP2.
Volume: 162
Issue: 6
Pages: 397-410
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32988222 | J:339099
First Author: Qi Z
Year: 2021
Journal: Circulation
Title: PCSK9 (Proprotein Convertase Subtilisin/Kexin 9) Enhances Platelet Activation, Thrombosis, and Myocardial Infarct Expansion by Binding to Platelet CD36.
Volume: 143
Issue: 1
Pages: 45-61
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31962046 | -
First Author: Burdick DJ
Year: 2020
Journal: ACS Chem Biol
Title: Design of Organo-Peptides As Bipartite PCSK9 Antagonists.
Volume: 15
Issue: 2
Pages: 425-436
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27678423 | -
First Author: Dixon DL
Year: 2016
Journal: J Clin Lipidol
Title: A review of PCSK9 inhibition and its effects beyond LDL receptors.
Volume: 10
Issue: 5
Pages: 1073-80
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28825733 | -
First Author: Zhang Y
Year: 2017
Journal: Nat Struct Mol Biol
Title: Discovery of a cryptic peptide-binding site on PCSK9 and design of antagonists.
Volume: 24
Issue: 10
Pages: 848-856
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30653992 | -
First Author: Ultsch M
Year: 2019
Journal: J Mol Biol
Title: Identification of a Helical Segment within the Intrinsically Disordered Region of the PCSK9 Prodomain.
Volume: 431
Issue: 5
Pages: 885-903
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18498363 | -
First Author: Dewpura T
Year: 2008
Journal: FEBS J
Title: PCSK9 is phosphorylated by a Golgi casein kinase-like kinase ex vivo and circulates as a phosphoprotein in humans.
Volume: 275
Issue: 13
Pages: 3480-93
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8796313 | -
 
First Author: Samal B
Year: 1996
Journal: Adv Exp Med Biol
Title: Cloning and expression of the gene encoding a novel proteinase from Tritirachium album limber.
Volume: 379
Pages: 95-104
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4373242 | -
First Author: Ebeling W
Year: 1974
Journal: Eur J Biochem
Title: Proteinase K from Tritirachium album Limber.
Volume: 47
Issue: 1
Pages: 91-7
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20446009 | -
First Author: Liu SQ
Year: 2011
Journal: J Mol Model
Title: The effect of calciums on molecular motions of proteinase K.
Volume: 17
Issue: 2
Pages: 289-300
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31978056 | J:284050
First Author: Emmer BT
Year: 2020
Journal: PLoS One
Title: Murine Surf4 is essential for early embryonic development.
Volume: 15
Issue: 1
Pages: e0227450
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36288700 | J:334128
First Author: Stomberski CT
Year: 2022
Journal: Cell Rep
Title: A multienzyme S-nitrosylation cascade regulates cholesterol homeostasis.
Volume: 41
Issue: 4
Pages: 111538
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33432099 | J:321984
First Author: Levine JA
Year: 2021
Journal: Sci Rep
Title: Role of PAI-1 in hepatic steatosis and dyslipidemia.
Volume: 11
Issue: 1
Pages: 430
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38648484 | J:358508
First Author: Benedicto I
Year: 2024
Journal: Proc Natl Acad Sci U S A
Title: Exacerbated atherosclerosis in progeria is prevented by progerin elimination in vascular smooth muscle cells but not endothelial cells.
Volume: 121
Issue: 18
Pages: e2400752121
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21343340 | J:172834
First Author: Scotti E
Year: 2011
Journal: Mol Cell Biol
Title: Targeted disruption of the idol gene alters cellular regulation of the low-density lipoprotein receptor by sterols and liver x receptor agonists.
Volume: 31
Issue: 9
Pages: 1885-93
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29162602 | J:277975
First Author: Yu P
Year: 2018
Journal: Arterioscler Thromb Vasc Biol
Title: Rosuvastatin Reduces Aortic Sinus and Coronary Artery Atherosclerosis in SR-B1 (Scavenger Receptor Class B Type 1)/ApoE (Apolipoprotein E) Double Knockout Mice Independently of Plasma Cholesterol Lowering.
Volume: 38
Issue: 1
Pages: 26-39
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27171436 | J:248959
First Author: Topchiy E
Year: 2016
Journal: PLoS One
Title: Lipopolysaccharide Is Cleared from the Circulation by Hepatocytes via the Low Density Lipoprotein Receptor.
Volume: 11
Issue: 5
Pages: e0155030
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30451917 | J:268127
First Author: Håversen L
Year: 2018
Journal: Sci Rep
Title: Vimentin deficiency in macrophages induces increased oxidative stress and vascular inflammation but attenuates atherosclerosis in mice.
Volume: 8
Issue: 1
Pages: 16973
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30026278 | J:284938
First Author: Jarrett KE
Year: 2018
Journal: Arterioscler Thromb Vasc Biol
Title: Somatic Editing of Ldlr With Adeno-Associated Viral-CRISPR Is an Efficient Tool for Atherosclerosis Research.
Volume: 38
Issue: 9
Pages: 1997-2006
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26334034 | J:258605
First Author: Armstrong SM
Year: 2015
Journal: Cardiovasc Res
Title: A novel assay uncovers an unexpected role for SR-BI in LDL transcytosis.
Volume: 108
Issue: 2
Pages: 268-77
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32978273 | J:310442
First Author: LeBlond ND
Year: 2020
Journal: J Lipid Res
Title: Myeloid deletion and therapeutic activation of AMPK do not alter atherosclerosis in male or female mice.
Volume: 61
Issue: 12
Pages: 1697-1706
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26592663 | J:233188
First Author: Liu M
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Impact of age and sex on the development of atherosclerosis and expression of the related genes in apoE deficient mice.
Volume: 469
Issue: 3
Pages: 456-62
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36193893 | J:330402
   
First Author: Tang VT
Year: 2022
Journal: Elife
Title: Hepatic inactivation of murine <i>Surf4</i> results in marked reduction in plasma cholesterol.
Volume: 11
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37142180 | J:348549
 
First Author: Dong YT
Year: 2023
Journal: Neuroscience
Title: Resveratrol Attenuates the Disruption of Lipid Metabolism Observed in Amyloid Precursor Protein/Presenilin 1 Mouse Brains and Cultured Primary Neurons Exposed to Aβ.
Volume: 521
Pages: 134-147
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23382078 | J:203323
First Author: Scotti E
Year: 2013
Journal: Mol Cell Biol
Title: IDOL stimulates clathrin-independent endocytosis and multivesicular body-mediated lysosomal degradation of the low-density lipoprotein receptor.
Volume: 33
Issue: 8
Pages: 1503-14
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29930001 | J:285150
First Author: Cansby E
Year: 2018
Journal: Arterioscler Thromb Vasc Biol
Title: STK25 Regulates Cardiovascular Disease Progression in a Mouse Model of Hypercholesterolemia.
Volume: 38
Issue: 8
Pages: 1723-1737
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Publication
33472399 | J:321054
First Author: Hosseini Z
Year: 2021
Journal: Arterioscler Thromb Vasc Biol
Title: Resolvin D1 Enhances Necroptotic Cell Clearance Through Promoting Macrophage Fatty Acid Oxidation and Oxidative Phosphorylation.
Volume: 41
Issue: 3
Pages: 1062-1075
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Publication
30796085 | J:294153
First Author: Yang L
Year: 2019
Journal: J Lipid Res
Title: LPA receptor 4 deficiency attenuates experimental atherosclerosis.
Volume: 60
Issue: 5
Pages: 972-980
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Publication
39815082 | J:361417
First Author: Yntema T
Year: 2025
Journal: Sci Rep
Title: The impact of a humanized bile acid composition on atherosclerosis development in hypercholesterolaemic Cyp2c70 knockout mice.
Volume: 15
Issue: 1
Pages: 2100
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Publication
36073351 | J:348139
First Author: Silvestro M
Year: 2022
Journal: Arterioscler Thromb Vasc Biol
Title: The Nonproteolytic Intracellular Domain of Membrane-Type 1 Matrix Metalloproteinase Coordinately Modulates Abdominal Aortic Aneurysm and Atherosclerosis in Mice-Brief Report.
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Journal: J Biol Chem
Title: The Proprotein Convertase Subtilisin/Kexin Type 9-resistant R410S Low Density Lipoprotein Receptor Mutation: A NOVEL MECHANISM CAUSING FAMILIAL HYPERCHOLESTEROLEMIA.
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Title: Absence of Nicotinamide Nucleotide Transhydrogenase in C57BL/6J Mice Exacerbates Experimental Atherosclerosis.
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Title: Multifaceted roles of Meg3 in cellular senescence and atherosclerosis.
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Title: Cargo-Specific Role for Retriever Subunit VPS26C in Hepatocyte Lipoprotein Receptor Recycling to Control Postprandial Triglyceride-Rich Lipoproteins.
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Title: Endothelial ADAM10 controls cellular response to oxLDL and its deficiency exacerbates atherosclerosis with intraplaque hemorrhage and neovascularization in mice.
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Title: ADCY9 (Adenylate Cyclase Type 9) Inactivation Protects From Atherosclerosis Only in the Absence of CETP (Cholesteryl Ester Transfer Protein).
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Title: Sex-Specific Mechanisms of Resistance Vessel Endothelial Dysfunction Induced by Cardiometabolic Risk Factors.
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